Person: YILDIZ, KEMALETTİN
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Publication Open Access Serum endocan levels in women with restless legs syndrome.(2015-11-19) CELIK, K; ÇıKRıKÇıOĞLU, MA; HALAC, G; KILIC, ERDEM; AYHAN, S; OZARAS, N; Karatoprak, CUMALİ; YILDIZ, KEMALETTİN; YILDIZ, RS; ZORLU, MEHMET; CAKIRCA, MUSTAFA; KıSKAÇ, MUHARREM; KILIÇ, ERDEM; YILDIZ, KEMALETTİN; ZORLU, MEHMET; KARATOPRAK, CUMALİ; ÇAKIRCA, MUSTAFA; KISKAÇ, MUHARREMBackground: Endocan is a recently introduced marker of endothelial dysfunction. The objective of this study was to compare serum endocan levels in patients with restless legs syndrome (RLS) and control subjects in order to elucidate whether RLS is associated with endothelial dysfunction. Methods: A total of 31 drug naïve female patients with RLS and 31 age- and BMI-matched women were included in the study. Patients with pathological or physiological conditions or with a history of medication use that could potentially influence endothelial functions were excluded, as well as those with alcohol or drug abuse history. The two groups were compared with routine blood tests and serum endocan levels. Results: Patients with RLS had lower serum endocan levels than the controls (P=0.037). There was a negative bivariate correlation between RLS severity score and serum endocan levels (r=-0.406, P=0.023). While white blood cell count was significantly higher in RLS group, 25-hydroxy vitamin D3, vitamin B12, transferrin saturation rate, and HDL-cholesterol were significantly lower. Creatininemia and diastolic blood pressure were also marginally insignificantly lower in RLS group. Due to the presence of differences between two groups in these variables, a linear regression analysis was performed that showed a positive association between endocan and creatininemia (β=0.310, P=0.022), and a negative association between endocan and RLS (β=-0.502, P,0.001). Conclusion: The results of this study seem to suggest that patients with RLS may have better endothelial functions when compared with the general population and that these patients may be better protected against atherosclerosisPublication Open Access Association of calcium channel blocker use with lower hemoglobin levels in chronic kidney disease(2013-09-01) Karatoprak, CUMALİ; CIKRIKCIOGLU, M. A.; Cakirca, MUSTAFA; Kiskac, MUHARREM; Zorlu, MEHMET; Cetin, GÜVEN; YILDIZ, KEMALETTİN; ERKOC, R.; ALAY, M.; Erkal, S.; Erkal, S. N.; DOGAN, S.; Kazancioglu, RÜMEYZA; KARATOPRAK, CUMALİ; ÇAKIRCA, MUSTAFA; KISKAÇ, MUHARREM; ZORLU, MEHMET; ÇETİN, GÜVEN; YILDIZ, KEMALETTİN; KAZANCIOĞLU, RÜMEYZAAim: To search whether calcium channel blockers (CCBs) are associated with lower hemoglobin levels in chronic kidney disease (CKD) patients who are not on renal replacement therapy (RRT), vitamin D and anti-anemic treatment. Patients and methods: CKD patients were classified into two groups. Patients on CCBs treatment (103 patients) and patients not using CCBs (104 patients) were compared cross-sectionally regarding clinical findings, complete blood count (CBC), biochemistry and regular medication use. Patients with polycystic kidney disease, comorbidities that could influence CBC other than iron deficiency of obscure origin, patients receiving RRT, erythropoietin (EPO), vitamin D, phosphate binders and drugs that could influence CBC were excluded. Under dependent variable of CCB use, all significantly different independent variables were subjected to multivariate binary logistic regression analysis (MBLRA). Results: Lower hemoglobin, lower bilirubinemia, higher serum EPO, higher systolic blood pressure were observed in CCB users. Two groups were similar concerning age, gender, BMI, CKD etiology, CKD stage, pretibial edema prevalence, cardiothoracic index, diastolic blood pressure, corrected reticulocyte count, BUN, creatinine, eGFR, proBNP, parathormone, alkaline phosphatase, phosphorous, corrected calcemia, sCRP, relative EPO deficiency and prevalence of relative EPO deficient patients. Groups were comparable regarding comorbidities, types and usage frequencies of all antihypertensive medications other than CCBs. Higher systolic blood pressure and lower hemoglobin were significantly associated with CCB use after MBLRA. Conclusions: Hemoglobin was significantly lower in CCB users compared to non-users, among CKD patients who did not receive RRT, EPO, phosphate binders, vitamin D, iron, vitamin B12 and folic acid.Publication Metadata only Kronik Yara Yönetimi(Nobel Tıp Kitapevi, 2022-03-01) Kirazoğlu A.; Yıldız K.; Güneren E.; KİRAZOĞLU, AHMET; YILDIZ, KEMALETTİN; GÜNEREN, ETHEMPublication Metadata only Nodule on scalp: As a metastatic gastric cancer(2020-11-01) Yeniocak A.; ÇAMLI M. F.; GEÇER M.; YILDIZ K.; YENİOCAK, ALİ; ÇAMLI, MEHMET FATİH; GEÇER, MELİN; YILDIZ, KEMALETTİNPublication Metadata only Neutrophil Elastase Inhibitor Increases Flap Survival in Experimental Degloving Injuries.(2018-07-25) Yuce E.; Sevim K. Z.; Kiyak M. V.; Yildiz K.; Dagdelen D.; Irmak F.; Karsidag S.; Kilic U.; YILDIZ, KEMALETTİNPublication Open Access Gastroenterology cases of cutaneous leukocytoclastic vasculitis.(2013-01-01) SENTURK, H; ARABACI, ELİF; YILDIZ, KEMALETTİN; CAKIRCA, MUSTAFA; ÇıKRıKÇıOĞLU, MA; ERGUN, F; DANALIOGLU, A; KOCAMAN, O; KARATOPRAK, CUMALİ; ARABACI, ELİF; YILDIZ, KEMALETTİN; ÇAKIRCA, MUSTAFA; ŞENTÜRK, HAKANRarely, leukocytoclastic vasculitis can result from ischemic colitis, inflammatory bowel disease, and cryoglobulinemia. There is no established standard for the treatment of leukocytoclastic vasculitis associated with gastroenterologic diseases. This paper presents three cases of leukoytoclastic vasculitis, each of which is associated with a different gastroenterologic condition: ischemic colitis, Crohn’s disease, and chronic hepatitis C. Each condition went into remission by treatment of leukocytoclastic vasculitis, regardless of the underlying disease.Publication Metadata only Kraniyofasiyal Fibröz Displazi(Hipokrat Yayınevi, 2022-07-01) Yıldız K.; Çamlı M. F.; YILDIZ, KEMALETTİN; ÇAMLI, MEHMET FATİHPublication Metadata only Farklı Cerrahi Flep Geciktirme Yöntemlerinin Etkinliği ve Sistemik Toksisiteleri(2022-05-25) Kirazoğlu A.; Mirapoğlu S. L.; Kılıç Ü.; Güneren E.; Sağır H. Ö.; Koçyiğit A.; Yeşiloğlu N.; Canter H. İ.; Çay A.; Yıldız K.; KİRAZOĞLU, AHMET; GÜNEREN, ETHEM; KOÇYİĞİT, ABDÜRRAHİM; YILDIZ, KEMALETTİNIntroduction: The surgical flap delaying has been shown to be effective in preventing partial flap loss or in preparing larger flaps. However, there is no gold standard flap delay method in the literature. In this study, the authors aimed to compare 3 types of surgical delay methods to determine which model would increase more flap survival. The authors also investigated the effect of delay methods on circulating mononuclear leukocytes as a parameter of DNA damage. Materials and Methods: Twenty-four Sprague-Dawley male rats were divided into 4 groups. All subjects had a 10 × 3 cm modified McFarlane flap. Surface area measurements, biopsies, and blood samples were taken on the day of sacrification; 7th day for the control group and 14th day for delay groups. Results: Between incisional surgery delay groups, a significant difference was found in necrosis and apoptosis in the bipedicled group, and only necrosis in the tripedicled group compared to the control. In terms of DNA damage, it was found higher in all experimental groups than in the control group. Conclusions: Both incisional surgical delay procedures’ results were meaningfully effective when only incisions were made without the elevation of flaps. In conclusion, bipedicled incisional surgical delay seems to be the most effective method in McFarlane experimental flap model whereas two-staged surgeries may increase the risk of systemic toxicityPublication Metadata only Diyabetik El Enfeksiyonlarının Yönetimi; 10 Yıllık Deneyim ve Literatür İncelemesi(2023-11-01) KOÇ C.; ÇAMLI M. F.; EVİN N.; YILDIZ K.; Ergün S. S.; KOÇ, CAN; ÇAMLI, MEHMET FATİH; EVİN, NUH; YILDIZ, KEMALETTİN; ERGÜN, SELMAPublication Metadata only COVID-19 salgını sırasında diyabetik ayak ülserlerinin tedavisi için öneriler(2021-11-14) Kelahmetoğlu O.; Çamlı M. F.; Kirazoğlu A.; Erbayat Y.; Asgarzade S.; Durgun U.; Mehdizade T.; Yeniocak A.; Yıldız K.; Sönmez Ergün S.; et al.; ÇAMLI, MEHMET FATİH; ERBAYAT, YUSUF; YILDIZ, KEMALETTİN; ERGÜN, SELMA