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YILDIZ, KEMALETTİN

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KEMALETTİN
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YILDIZ
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2020 - 20227
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Author: GÜNEREN, ETHEM × Start date: 2020 × End date: 2022 ×

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Now showing 1 - 7 of 7
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    Sınıflandırma Dışı Damak Yarığı
    (2021-11-10T00:00:00Z) ASGARZADE, SUSAN; MEHDIZADE, TURAN; ÖZCAN, EBRU DIANA; EVİN, NUH; YILDIZ, KEMALETTİN; GÜNEREN, ETHEM; ASGARZADE, SUSAN; MEHDIZADE, TURAN; EVİN, NUH; YILDIZ, KEMALETTİN; GÜNEREN, ETHEM
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    The Role of Staged Cryosurgery and Three-Dimensional Computed Tomography Integrated Navigation System in the Surgical Management of Severe Involvement of Craniofacial Polyostotic Fibrous Dysplasia
    (2020-01-01T00:00:00Z) Dündar, Tolga Turan; YILDIZ, KEMALETTİN; DÜNDAR, TOLGA TURAN; MEHDIZADE, TURAN; GÜNEREN, ETHEM
    Fibrous dysplasia (FD) is a developmental bone disorder caused by the hamartamatous proliferation of bone-forming cells. A 29-year-old male patient with diagnosis of FD was admitted to our clinic with the symptoms of severe craniomaxillofacial involvement of FD beginning from last year. Neurological examination revealed diplopia, horizontal nystagmus, conductive hearing loss, and partial vision loss. In his medical history, it was reported that he had undergone intramedullary nailing operation in his left femur due to a pathological fracture approximately 8 years ago in the orthopedics clinic of our institution. The patient underwent 3 consecutive surgeries by our plastic and neurosurgical team. The patient was followed-up in the neuro-intensive care unit between the surgical sessions and 1 week after the last operation. Afterwards, he was transferred to the neurosurgical department. No postoperative complication was detected. The preoperative signs were recovered. During his 6th month follow-up control-visit, all his preoperative symptoms were improved. In addition, the patient was satisfied with his postoperative cosmetic improvement. In conclusion, virtual surgical planning and intraoperative surgical navigation systems can make the challenging cases possible to operate with increasing
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    PublicationOpen Access
    Generation of Bone Tissue Using Adipose Tissue-derived Stem Cells
    (2021-07-01T00:00:00Z) Baygol, Emre Gonenc; GÜNEREN, Ethem; Karaaltin, Mehmet Veli; Canter, Halil Ibrahim; Ozturk, Kahraman; Ovali, Ercument; Ozpur, Mustafa Aykut; YILDIZ, KEMALETTİN; Eyuboglu, Fatma; GÜNEREN, ETHEM; YILDIZ, KEMALETTİN
    Objective: Bone grafts and even bone substitutes do not meet all of the requirements of bony reconstructions. The aim of this study was to generate bone tissue from autologous adipose tissue-derived mesenchymal stem cells (ATDMSCs) and decellularised bone allografts. Methods: A 1.5 cm bone defect developed in the middle third of the rabbit's ulna. Reconstructions were carried out using miniplate and screws and interpositional autogenous bone grafts according to the designs of the groups: (1) No touch, (2) cryopreserved, (3) decellularised and (4) ATDMSCs-implanted decellularised bones. Before implantation, ATDMSCs in the last group were labelled with Q-dot and identified microscopically. Results: Graft recovery and irregular callus formation were observed in the first, second and forth groups. In the first group, the organisation of Haversian systems, the structure of the lacunae and the presence of canaliculi ossiums were observed; in the second group, approximately 40% of the Haversian canals contained blood vessels, and canaliculi ossiums in the form of thin filaments were found in 90% of the microscopically examined areas; in the third group, most Haversian canals were empty, most osteocyte canals were devoid of cells, and canaliculi ossiums were absent; in the fourth group, some of the Haversian canals contained blood vessels, and there were partly lacunae containing cells due to decellularisation, whereas in approximately 50% of the examined microscope areas, the presence of canaliculi ossiums with evidence of mesenchymal stem cells differentiated into osteocytes was demonstrated by Q-dot traced cells. Conclusion: In this study, the establishment of a proper niche environment for adipose-derived mesenchymal cells promotes their development into osteogenic cells.
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    Kronik Yara Yönetimi
    (Nobel Tıp Kitapevi, 2022-03-01) Kirazoğlu A.; Yıldız K.; Güneren E.; KİRAZOĞLU, AHMET; YILDIZ, KEMALETTİN; GÜNEREN, ETHEM
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    Geniş Gluteal ve Trokanterik Bölge Defektlerinin Tensör Fasya Lata Flebiyle Rekonstrüksiyonu
    (2021-11-14T00:00:00Z) EKİCİ, REHA FURKAN; EVİN, NUH; YILDIZ, KEMALETTİN; GÜNEREN, ETHEM; EKİCİ, REHA FURKAN; EVİN, NUH; YILDIZ, KEMALETTİN; GÜNEREN, ETHEM
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    PublicationOpen Access
    Boneless Maxillary Reconstruction
    (2020-01-01T00:00:00Z) Kelahmetoğlu, Osman; Güneren, Ethem; Kuzu, Ismail Melih; Yıldız, Kemalettin; KELAHMETOĞLU, OSMAN; GÜNEREN, ETHEM; YILDIZ, KEMALETTİN
    Objective: Although the midface is supported by maxillary bone, reconstruction of maxillary bony defects does not always require osseous reconstruction. A series of maxillary facial defects of moderate to severe sizes (Brown and Shaw 4-6) uniformly reconstructed with myocutaneous free flaps is presented. Methods: Retrospective analysis was done for consecutive 10 cases between 2013-18. Seven of the cases had defects caused by oncological resection and 3 defects caused by trauma. Free vertically oriented rectus abdominis (fVRAM) flap was used to reconstruct these defects. The mean age of patients was 42.9 years (range=20-71 years). All flaps survived and 2 flaps had small skin island problems. Rapid recovery, low morbidity, acceptable oral competency, and satisfactory cosmetic appearance were obtained with the reconstruction using fVRAM flaps. Conclusion: According to our limited experience, acceptable reconstruction of extensive maxillary defects can be done with using only soft tissue flap, which is versatile and safe.
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    Farklı Cerrahi Flep Geciktirme Yöntemlerinin Etkinliği ve Sistemik Toksisiteleri
    (2022-05-25) Kirazoğlu A.; Mirapoğlu S. L.; Kılıç Ü.; Güneren E.; Sağır H. Ö.; Koçyiğit A.; Yeşiloğlu N.; Canter H. İ.; Çay A.; Yıldız K.; KİRAZOĞLU, AHMET; GÜNEREN, ETHEM; KOÇYİĞİT, ABDÜRRAHİM; YILDIZ, KEMALETTİN
    Introduction: The surgical flap delaying has been shown to be effective in preventing partial flap loss or in preparing larger flaps. However, there is no gold standard flap delay method in the literature. In this study, the authors aimed to compare 3 types of surgical delay methods to determine which model would increase more flap survival. The authors also investigated the effect of delay methods on circulating mononuclear leukocytes as a parameter of DNA damage. Materials and Methods: Twenty-four Sprague-Dawley male rats were divided into 4 groups. All subjects had a 10 × 3 cm modified McFarlane flap. Surface area measurements, biopsies, and blood samples were taken on the day of sacrification; 7th day for the control group and 14th day for delay groups. Results: Between incisional surgery delay groups, a significant difference was found in necrosis and apoptosis in the bipedicled group, and only necrosis in the tripedicled group compared to the control. In terms of DNA damage, it was found higher in all experimental groups than in the control group. Conclusions: Both incisional surgical delay procedures’ results were meaningfully effective when only incisions were made without the elevation of flaps. In conclusion, bipedicled incisional surgical delay seems to be the most effective method in McFarlane experimental flap model whereas two-staged surgeries may increase the risk of systemic toxicity