Person: VEHAPOĞLU TÜRKMEN, AYSEL
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Publication Metadata only Is molluscum contagiosum related to zinc deficiency in children? Effectiveness of oral zinc sulfate therapy in lesion regression.(2021-11-01T00:00:00Z) Vehapoglu, Aysel; VEHAPOĞLU TÜRKMEN, AYSELPublication Metadata only Clinical symptoms and microbiological findings in prepubescent girls with vulvovaginitis.(2022-07-09T00:00:00Z) Vehapoglu, Aysel; Kıyak, Merve Celep; VEHAPOĞLU TÜRKMEN, AYSELPublication Metadata only Association between Consumption of Cow-s Milk and Iron Deficiency Anemia in Children: Are There Roles for Hepcidin-25/Ferroportin? A Case-Control Study(2020-07-01T00:00:00Z) Vehapoglu, Aysel; Ozgurhan, Gamze; USTABAŞ KAHRAMAN, Feyza; ÇAKIN, ZEYNEP EBRU; SÜMBÜL, BİLGE; VEHAPOĞLU TÜRKMEN, AYSEL; USTABAŞ KAHRAMAN, FEYZA; ÇAKIN, ZEYNEP EBRU; SÜMBÜL, BİLGESystemic iron homeostasis is regulated by the interaction of the peptide hormone, hepcidin and the iron exporter, ferroportin. The objective was to investigate the relationship between the consumption of cow-s milk and iron deficiency anemia in children 2-10 years old and its association with the hepcidin-25 and ferroportin concentrations. The study population consisted of 187 prepubescent children of similar ideal body weight (IBW:90-120%); 82 children with iron deficiency anemia (37girls and 45boys; 4.27 +/- 0.28 years) and 105 (47girls and 58boys; 4.25 +/- 0.34 years) healthy age-sex-matched controls. Serum fasting hepcidin-25/ferroportin concentrations were measured by enzyme immunoassay in all subjects. Mean cow-s milk consumption in the anemic group (373 +/- 248 mL/d) tended to be higher than that in the control group (320 +/- 226 mL/d), but the result was not statistically significant (p = 0.063).The mean hepcidin-25 level was significantly higher in the anemic group (19.5 +/- 18.4 ng/mL) than in the healthy controls (11.0 +/- 10.7, p < 0.001). The mean ferroportin level was lower in the anemic group (21.04 +/- 5.74 ng/mL) than in the healthy controls (22.68 +/- 4.77 ng/ml, p = 0.037). Consuming cow-s milk was not associated with IDA in prepubertal children, provided that it was adequately supplemented with iron-enriched foods. We observed a significant increase in hepcidin-25 levels and a decrease in ferroportin levels in children with iron deficiency anemia compared with healthy controls. Children who consumed more cow-s milk had higher levels of hepcidin-25. Iron deficiency anemia is not a concern when cow-s milk is given to children if the complementary foods are rich in iron.Publication Metadata only Total oxidant and antioxidant status and paraoxonase 1 levels of children with noncystic fibrosis bronchiectasis(2020-02-13T00:00:00Z) Gedik, AH; Çakir, Erkan; Vehapoğlu, Türkmen; Özer, ÖF; Kaygusuz, SB; ÇAKIR, ERKAN; VEHAPOĞLU TÜRKMEN, AYSEL; ÖZER, ÖMER FARUKPublication Open Access New association between idiopathic scoliosis and Luckenschadel skull (lacunar skull).(2021-12-07T00:00:00Z) Vehapoglu, Aysel; VEHAPOĞLU TÜRKMEN, AYSELObjective: Luckenschadel skull is a skull that is radiologically characterized by lacunae in the cranial vault. To date, although the association between neurological abnormalities and scoliosis is well recognized, no relationship between idiopathic scoliosis and a lacunar skull has been defined. We explored the incidence and time courses of lacunar skulls in patients with idiopathic scoliosis. Materials and methods: Spinal X-rays of 3,170 children aged 6-16 years with idiopathic scoliosis evaluated from October 2010 to August 2020 were examined for the presence of an irregular inner calvarial table indicative of a Luckenschadel skull. A total of 1,760 (55.5%) of the 3,170 images included the skull. We also explored the frequency of intraspinal abnormalities in children with lacunar skull images who underwent spinal magnetic resonance imaging. Results: The study population consisted of 1,760 children, 1,203 girls (68.4%) and 557 (31.6%) boys. A total of 268 (15.2%) clearly evidenced lacunar skulls in their radiographs; 186 (69.4%) girls (11.3 ± 4.3 years) and 82 (30.6%) boys (12.6 ± 3.3 years). Two of the 56 patients (3.6%) who underwent spinal MRI had intraspinal abnormalities (isolated Chiari malformation-I). No additional neurological problems were detected in children with lacunar skulls. Conclusion: We conclude that the lacunar skull is very common in children with idiopathic scoliosis who lack any other neurological pathology. The lacunar skull does not disappear even in adolescence. Although previous publications have stated that lacunar skull disappears over time in radiographic images, we observed that it became more noticeable over time in children with scoliosis.Publication Metadata only Is overweight/obesity a risk factor for atopic allergic disease in prepubertal children? A case-control study(2021-01-01T00:00:00Z) VEHAPOĞLU TÜRKMEN, Aysel; ÇAKIN, ZEYNEP EBRU; USTABAŞ KAHRAMAN, Feyza; NURSOY, MUSTAFA ATİLLA; TOPRAK, ALİ; VEHAPOĞLU TÜRKMEN, AYSEL; ÇAKIN, ZEYNEP EBRU; USTABAŞ KAHRAMAN, FEYZA; NURSOY, MUSTAFA ATİLLA; TOPRAK, ALİObjectives: It is unclear whether body weight status (underweight/normal weight/overweight/obese) is associated with allergic disease. Our objective was to investigate the relationship between body weight status (body mass index; BMI) and atopic allergic disease in prepubertal children, and to compare children with atopic allergic diseases with non atopic healthy children.Publication Open Access A Rare Presentation of Acquired Laryngomalacia and Tracheomalacia in a Child Associated with Apricot Sulfurization(2020-12-01T00:00:00Z) Vehapoğlu Türkmen, Aysel; Çakır, Erkan; Uzuner, Selçuk; Çalım, Ömer Faruk; Yazan, Hakan; VEHAPOĞLU TÜRKMEN, AYSEL; ÇAKIR, ERKAN; UZUNER, SELÇUK; ÇALIM, ÖMER FARUK; YAZAN, HAKANSulfur fumigation has come to replace traditional sun drying methods for drying fruits over the years around the world as it is a cheaper and faster method because of its pesticidal and anti-bacterial properties. We report the case of an 11-year-old boy with acquired severe biphasic stridor who was exposed to extremely high concentrations of sulfur dioxide (SO2) during apricot sulfurization processes with his mother. The patient's bronchoscopy revealed severe glottic and subglottic damage. Exposure to SO2 is a health risk, particularly for individuals who are sulfide-sensitive, especially in childhood. The pulmonary epithelium may be directly injured by inhaled toxic substances at various levels of the respiratory system. To the best of our knowledge, this is the first case reported of acquired airway damage associated with sulfurization in a pediatric patient without a known history of any respiratory disease or symptoms.Publication Metadata only Impact of presence of paediatric palliative care units in hospitals on the confidence, knowledge and attitudes of paediatricians: the case of Turkey(2022-08-01T00:00:00Z) Vehapoğlu Türkmen, Aysel; VEHAPOĞLU TÜRKMEN, AYSELBackground: Paediatric palliative eare (PPC) focuses on improving the quality of life of children dealing with life-threatening conditions, as well as their families. Aims: To evaluate the knowledge and attitudes of paediatricians regarding palliative eare in Turkey and the impact of PPC units on their confidence and symptom management abilities. Methods: This was a multicentre descriptive study conducted in 2019. A questionnaire consisting of 24 questions and 4 parts on palliative eare was prepared. Paediatricians in hospitals with or without PPC units completed the questionnaire. Analyses were performed using NCSS 10 (2015) software. Results: There were 199 participants in the study, out of which 55 (27.6%) received palliative eare training. One hundred and sixty-seven (83.9%) paediatricians defined palliative care as improving the quality of life of patients in the terminal period, and 77 (38.7%) stated that palliative care can be started after diagnosis. The groups of patients who would benefit from palliative eare were most frequently identified as those with diseases that could not be cured (e.g. cystic fibrosis). Paediatricians with a PPC unit in their work environment, compared with those without a PPC unit, were significantly more competent in pain management (36.8% vs 6.4%, P < 0.001), symptom management (42.1% vs 19.2%, P < 0.001), and coping with the psychosocial problems of end-stage paediatric patients (36.8% vs 8.4%, P < 0.001). Conclusion: PPC units in hospitals contributed to paediatricians- ability to manage symptoms and communicate with families. The number of PPC units should be increased, especially in developing countries such as Turkey.