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ÖZTURAN, ORHAN

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Author: YENİGÜN, ALPER × Rights: info:eu-repo/semantics/openAccess ×

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Now showing 1 - 10 of 11
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    PublicationOpen Access
    Protective and therapeutic effects of pyrrolidine dithiocarbamate in a rat tongue cancer model created experimentally using 4-nitroquinoline 1-oxide.
    (2020-11-01T00:00:00Z) Doğan, R; Hafız, AM; Gucin, Z; Ozer, OF; Ozturan, O; Yenigun, Alper; DOĞAN, REMZI; GÜCİN, ZÜHAL; ÖZER, ÖMER FARUK; YENİGÜN, ALPER; ÖZTURAN, ORHAN
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    PublicationOpen Access
    Angiofibroma Localized in the Sphenoid Sinus
    (2017-01-01) Yenigun, ALPER; Aksoy, Fadlullah; Vural, Omer; Ozturan, ORHAN; YENİGÜN, ALPER; AKSOY, FADLULLAH; VURAL, ÖMER; ÖZTURAN, ORHAN
    Juvenile nasopharyngeal angio-broma is the most common benign tumor of the nasopharynx with complaints of unilateral nasal obstruction and recurrent nosebleeds in the young male population. Despite being a benign tumor, it can be aggressively destructive in surrounding tissues and bones by acting locally. (e gold standard treatment method is the surgical excision of the tumor. (is case report is a case of angio-broma, a 32-year-old asymptomatic male patient with no evidence of clinical signs and endoscopic examination, which is recognized as a localized vascular mass lesion in the right sphenoid sinus on the cranial MR imaging. We prepared this case report that may represent an angio-broma localized only within the sphenoid sinus which is very rare in the literature.
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    PublicationOpen Access
    Association of accessory sphenoid septa with variations in neighbouring structures
    (2017-01-01) AKSOY, FEYZA MÜBERRA; ÖZTURAN, ORHAN; GOKTAS, S.S.; YENİGÜN, ALPER; YENİGÜN, ALPER; AKSOY, FADLULLAH; ÖZTURAN, ORHAN
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    Key stone plasty and asymmetric hump resection in crooked nose deformity
    (2022-09-01) Balikci H.; YENİGÜN A.; ÇELİK İ.; AKSOY F.; DOĞAN R.; ÖZTURAN O.; YENİGÜN, ALPER; ÇELİK, İSMAİL; AKSOY, FADLULLAH; DOĞAN, REMZI; ÖZTURAN, ORHAN
    © 2022 Elsevier Inc.Objective: The aim of this study is to propose a new approach in crooked nose deformity with key-stone plasty and asymmetric hump resection. Method: Twelve patients with crooked nose deformities were operated using the open rhinoplasty technique. Our method, unlike other methods, has two different steps. Following asymmetric hump resection, cartilaginous and osseous septum were cut separated at the key stone area or more caudally and fix the septum with sutures again by allowing them to slide over each other in a way that directs the septum to the midline. If there is an inability to reveal the septum, we apply a longer spreader graft to the cartilage septum side. Results: The mean ages were 27.4 years. The mean follow-up time of the patients was 19.1 months. No complications were observed due to this technique. This technique was effective in the treatment of all our patients with crooked nose deformities. Conclusion: A novel surgical approach with key-stone plasty and asymmetric hump resection method was proposed in crooked nose deformity with a video animation.
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    PublicationOpen Access
    Dry Eye and Dry Nose Caused by the Effect of Allergic Rhinitis on Tear and Nasal Secretion Osmolarity.
    (2020-03-17T00:00:00Z) Elbay, A; Yenigun, A; Ozturan, O; Bayraktar, H; Ozer, Ömer Faruk; Dogan, R; YENİGÜN, ALPER; ELBAY, AHMET; ÖZDEM, ABDULLAH; ÖZER, ÖMER FARUK; DOĞAN, REMZI; ÖZTURAN, ORHAN
    Objective: Allergic rhinitis is a type 1 hypersensitivity reaction of immunoglobulin E in the rhino-ocular mucosa. This study was planned to demonstrate in patients with allergic rhinitis to evaluate changes in tear, nasal secretions, and blood osmolarity compared to healthy individuals. Method: Forty allergic rhinitis patients, 25 patients with acute upper respiratory tract infections, and 26 healthy participants were included in the study. Positive patients with allergic symptoms and skin prick test results were included in the allergic rhinitis group. Tear, nasal secretion, and blood osmolarity values were examined for the 3 groups. Result: In patients with allergic rhinitis, tear and nasal secretion osmolarity values were significantly higher in patients with acute upper respiratory tract infections and those of the healthy participants (P ¼ .001, P ¼ .038). In blood osmolarity measurements, there was no statistical difference between the groups (P ¼ .489). In patients with allergic rhinitis, Schirmer test results were significantly shorter than patients who had acute upper respiratory tract infection and those of the healthy participants (P ¼ .001, P ¼ .001). Patients with allergic rhinitis and acute upper respiratory tract infections had significantly shorter Schirmer test results than in healthy participants (P ¼ .001, P ¼ .001). Conclusion: Tear osmolarity was increased in allergic rhinitis patients, and this was thought to lead to dry eye findings. In the presence of allergic rhinitis, nasal secretions were found more hyperosmolar than tears. Nasal secretion osmolarity was higher in allergic rhinitis patients than in patients with acute upper respiratory tract infections and control group.
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    Diklofenak Sodyum, İbuprofen ve Parasetamol İçeren Nazal Analjezik Spreylerin Formülasyonu ve İn Vitro Toksisitesinin Değerlendirilmesi
    (2022-11-16) Yenigün A.; Sütcü A. O.; Yenigün V. B.; Sağıroğlu A. A.; Koçyiğit A.; Özturan O.; YENİGÜN, ALPER; SÜTÇÜ, AHMET ONUR; YENİGÜN, VILDAN BETÜL; KOÇYİĞİT, ABDÜRRAHİM; ÖZTURAN, ORHAN
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    PublicationOpen Access
    Investigation of the role of major respiratory viruses in the aetiology of nasal polyps using polymerase chain reaction technique
    (2014-04-01) YENIGUN, A.; AKSOY, FEYZA MÜBERRA; DOGAN, REMZİ; Yilmaz, F.; Ozturan, ORHAN; AKSOY, FADLULLAH; YENİGÜN, ALPER; DOĞAN, REMZI; ÖZTURAN, ORHAN; YENİGÜN, VILDAN BETÜL
    Objective: We aimed to identify the role of major respiratory viruses in the aetiology of human nasal polyps using polymerase chain reaction technique. Methods: Thirty patients with nasal polyps and a group of 20 healthy patients (control group) were included in this study. Mucosa was obtained from the polyps of patients with nasal polyposis and from the middle turbinate of the control group patients by means of biopsy. The samples were stored at -80 °C until molecular analysis by polymerase chain reaction was carried out. Results: In the control group, the human coronavirus and human rhinovirus were diagnosed in one of the patients and the human respiratory syncytial virus in another. In the group with nasal polyposis, the influenza B virus was identified in one of the patients and the human coronavirus in another. Conclusion: The results did not demonstrate a statistically significant relationship between nasal polyposis and respiratory viruses.
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    PublicationOpen Access
    Schwannoma Located in Nasopharyngeal Region.
    (2016-01-01) AKSOY, FEYZA MÜBERRA; SENTURK, EROL; Ozturan, ORHAN; YENIGUN, A; AKSOY, FADLULLAH; YENİGÜN, ALPER; ŞENTÜRK, EROL; ÖZTURAN, ORHAN
    Schwannoma is a tumor which has neuroectoderm origins, is hard, well-circumscribed, encapsulated, and slow growing benign cranial tumor, and may autonomously grow out of the nerve sheath of peripheral nerves. It is mostly seen in the head and neck region. In the paranasal sinus and nose areas, it is seen at a rate of 4%. The diagnosis is mostly made after histopathological examination. In this paper, a Schwannoma case observed in the nasopharyngeal region was presented in a 20-year-old female who had complaints of sleeping with open mouth, snoring, foreign body feeling in throat, and swallowing difficulties. The tumor was extracted via transoral approach. No recurrence was observed during follow-up over the next year. This case presentation is presented for the first time in the literature in English.
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    Monopolar elektrokoterin farklı güçlerde orta kulağa uygulanmasının iç kulağa etkisi
    (2022-11-20) Doğan R.; Çelik İ.; Başöz M.; Gedik Ö.; Yenigün A.; Eren S. B.; Şentürk E.; Özturan O.; DOĞAN, REMZI; ÇELİK, İSMAİL; BAŞÖZ, MELIHA; GEDİK, ÖZGE; YENİGÜN, ALPER; EREN, SABRİ BAKİ; ŞENTÜRK, EROL; ÖZTURAN, ORHAN
    AMAÇ: Çoğu ameliyatta kesi ve kanama kontrolü üçün monopolarelektrokoter yaygın olarak kullanılan cerrrahi bir enstrümandır. Ancakmonopolar elektorkoterin iç kulak üzerine etkisi bilinmemektedir.Çalışmamızda monopolar elektrokoterin iç kulak üzerine etkisinin odyo-lojik ve histopatolojik olarak incelenmesi amaçlandı.GEREÇ VE YÖNTEM: Çalışmamıza 32 adet sağlıklı dişi SpragueDawley sıçan (200-240 gr) dahil edildi. Ratlar her biri sekizerli olacakşekilde dört gruba ayrıldı.Grup 1: Monopolar elektrokoter-5WGrup 2: Monopolar elektrokoter-10WGrup 3: Monopolar elektrokoter-20WGrup 4: KontrolTüm gruplardaki ratlara bazal odyometrik ölçümler (DistorsiyonProduct Otoakustik Emisyon (DPOAE) ve Auditory Branstem Respones(ABR)) yapıldı.Grup 1,2 ve 3 e bazal odiyometrik ölçümler yapıldıktan sonra pro-montorium üzerine transtimpanik olarak monopolar elektrokoterin iğneucu ile mikroskop altında 2sn koterizasyon yapıldı. Kontrol grubuna her-hangibir işlem uygulanmadı. Tüm gruplarda çalışmanın 7 ve 14. günle-rinde odiyometrik ölçümler tekrarlandı.Çalışmanın odyolojik aşaması bittikten sonra ratların kokleaları eksizeedildi ve histopatolojik değerlendirme yapıldıBULGULAR: Grup 1,2,3 ve 4 ün bazal 7 ve 14. günlerindeki yüksekfrekans DPOAE amplitütleri (701 Hz, 997 Hz, 1401 Hz, 1977 Hz, 2834.Hz, 4002 Hz, 5636 Hz, 7988 Hz, 11288 Hz, 15991 Hz, 22608 Hz)(veABR eşikleri (10 kHz, 16kHz, 20 KhZ, 32kHz) arasında anlamlı farkyoktu (p>0,05).Tüm gruplarda kokleadaki spiral ganglion hücrelerinde ve sinir lifle-rinde hem hidropik dejenerasyon hemde nükleer kayıp gözlenmedi. Herüç grupda da histopatolojik değerlendirmede normal koklea yapısı göz-lenmiş olup gruplar arasında anlamlı fark bulunmamaktadır (p>0.05)SONUÇ: Farklı güçlerde (5W,10W ve 20 W) monopolar elektorkoteruygulaması sonrasında 7 ve 14. günlerde yapılan odyolojik ve hsitopa-tolojik değerlendirmelerde iç kulakta herhangibir zararlı etki saptanma-mıştır. Bu çalışma iç kulağın yakınında monopolar elektrokoterin güven-le kullanılabileceğini düşündümektedir.
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    PublicationOpen Access
    Nonodontogenic Cervical Necrotizing Fasciitis Caused by Sialadenitis.
    (2016-01-01) VURAL, O; VEYSELLER, B; YENIGUN, A; Ozturan, ORHAN; YENİGÜN, ALPER; VURAL, ÖMER; ÖZTURAN, ORHAN
    The term necrotizing fasciitis was described initially by Wilson in the 1950s [1]. Necrotizing fasciitis is a rapid spreading disease of the soft tissue, which includes the superficial fascia and subcutaneous layer of tissue [2–4]. Necrotizing fasciitis is associated with some situations in which the immune system is compromised, including diabetes mellitus (DM), elderly, acute, or chronic renal disease, postpartum period, alcoholism, intravenous (IV) drug use, malnutrition, malignancy, peripheral vascular disease, and radiation exposure [5]. Necrotizing fasciitis diagnosis is based on certain clinical features that include fulminant progression, presence of greyblack necrotic area, and easy separation of the superficial layers of the underlying tissue [2, 6]. Necrotizing fasciitis can emerge from a local infection region after a minor trauma, which leads to the entrance of site of the infection. The exact etiology of one-third of the necrotizing fasciitis patients is not clear [2, 3, 6]. If necrotizing fasciitis is not diagnosed and treated early, it is potentially a fatal disease [4, 7, 8]. This situation is based on the absence of early clinical findings, rapid progression of the disease, and the delay of surgical intervention [9]. Therefore, experience in the diagnosis and treatment of necrotizing fasciitis is quite limited. Involvement of the head and neck region is quite rare for necrotizing fasciitis patients [2]. In this region there are two types of necrotizing fasciitis and they include cervical and craniofacial involvement [10]. Mortality rates of cervical necrotizing fasciitis range from 7% to 20% depending on the width of the cervical lesion [11]. This case report is presented because, unlike most of the others, this case of necrotizing fasciitis is nonodontogenic, sialoadenitis induced cervical necrotizing fasciitis.