Person: SELÇUK, EMRE
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Publication Metadata only D-dimer Level is an Early Marker of Ischaemia/ reperfusion Injury After Coronary Artery Bypass Surgery(2019-12-01T00:00:00Z) Çakalağaoğlu, Kamil; Keski̇n, Gökhan; Altaş, Özge; Selçuk, Emre; SELÇUK, EMREIntroduction: Myocardial Ischaemia-Reperfusion (I-R) injury produces a spectrum of clinical cardiovascular outcomes after cardiac surgery. The pathogenesis of I-R injury is complex and involves the activation and amplification of several systemic and local proinflammatory pathways. The process of restoring blood flow to the ischaemic myocardium can induce injury and paradoxically reduce the beneficial effects of myocardial reperfusion. The objective of this study was to determine the correlation between cardiac markers such as the Mb fraction of the creatine kinase (CK-MB), troponin I (cTnI) and D-dimer levels as a marker of myocardial injury secondary to I-R injury after coronary artery bypass surgery. Patients and Methods: Herein, a prospective study was designed that included 50 consecutive coronary artery bypass grafting (CABG) patients. Pre and postoperative blood samples were taken due to study protocol and such markers as Mb fraction of the creatine kinase (CK-MB), troponin I (cTnI) and D-dimer were measured. Results: All three markers were significantly elevated in postoperative blood samples. The D-dimer level reached its peak at the first and another peak at 12th hour postoperatively. However, the peak serum values of CK-MB and cTnI occurred at 6th and 12th hour, respectively. Conclusion: We demonstrated that D-dimer levels as a marker of generated thrombin during reperfusion correlated with other well-known biochemical markers of myocardial damage in the postoperative period. In other words, D-dimer levels may stand as a marker of I-R-induced myocardial damage.Publication Metadata only Gebelik Döneminde Venöz Yetmezlik Semptomlarının Aberdeen Varıköz Ven Anketi ile Değerlendirilmesi ve Yaşam Kalitesini Etkileyen Faktörler(2019-10-29T00:00:00Z) Selçuk, Emre; Avni Bayraktar, Fatih; SELÇUK, EMREPublication Unknown Intraoperative Tissue-Immunosuppressive Therapy Reduces Rejection Episodes in Heart Transplant Recipients.(2018-09-25T00:00:00Z) Rabus, MB; Cekmecelioglu, D; Ata, P; Salihi, S; Selcuk, Emre; Balkanay, M; SELÇUK, EMREPublication Unknown The use of rivaroxaban in deep venous thrombosis associated with vena cava inferior agenesis(2019-10-01T00:00:00Z) Arikan, Ali Ahmet; Emre, Selcuk; Avni, Bayraktar Fatih; SELÇUK, EMREInferior vena cava agenesis is a rare anomaly which may result in deep vein thrombosis. There is no clear scientific evidence for the most effective therapeutic management, optimal duration, or the choice of anticoagulant therapy. Herein, we report an 18-year-old male case with deep vein thrombosis associated with inferior vena cava agenesis who was on rivaroxaban as a lifelong anticoagulation treatment for symptoms of venous stasis and the presence of heterozygotic thrombophilic mutations.Publication Unknown Pediatrik Kalp Cerrahisi Sonrası Gelişen Akut Böbrek Hasarının -Pediatrik Rıfle Kriterleri- Kullanılarak Değerlendirilmesi(2019-01-01T00:00:00Z) Selçuk, Emre; SELÇUK, EMREPublication Unknown Onkolojide Destek Tedaviler(2019-01-01T00:00:00Z) Selçuk, Emre; SELÇUK, EMRE