Person: KILIÇ, ERDEM
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Publication Open Access Spontaneous and Excellent Healing of Bilateral Brown Tumors in Mandible after Endocrinal Therapy and Subtotal Parathyroidectomy: Case Report with 4-Year Follow-Up(2018-01-01) YÜCESOY, TÜRKER; KILIÇ, ERDEM; DOĞRUEL, FATMA; BAYRAM, FAHRİ; ALKAN, ALPER; AKCAN, Alper Celal; ÖZTÜRK, FİGEN; YÜCESOY, TÜRKER; KILIÇ, ERDEM; ALKAN, ALPERPrimary hyperparathyroidism is an endocrine disorder occurring due to increased secretion of parathormone resulting in a complex of clinical, anatomical, and biochemical alterations. On the other hand, excision of a parathyroid adenoma can normalize the metabolic status. A 24-year-old man was referred to the hospital with bilateral swelling and spontaneous gingival bleeding from posterior of the mandible also with radiolucent well-demarcated lesions bilaterally in the mandibular third molar regions. After consultations, the patient was hospitalized in the endocrinology department where further tests were performed due to highly increased PTH level as 714 pg/ml. Bilateral brown tumors started to regress spontaneously, and no additional surgery was required after subtotal parathyroidectomy was performed. The presented case is the first patient whose bilateral brown tumors in the jaws spontaneously and totally healed after subtotal parathyroidectomy and endocrinal therapy who was strictly followed up for 4 years even though the lesions were associated with impacted third molars.Publication Open Access Reusing dental implants?: an experimental study for detecting the success rates of re-osseointegration(2018-06-19) Ulu, Murat; KILIÇ, ERDEM; SOYLU, EMRAH; KÜRKÇÜ, MEHMET; ALKAN, ALPER; KILIÇ, ERDEM; ALKAN, ALPERBackground: The aim of this study was to histomorphometrically compare the implant-host integration between retrieved implants and new implants. Methods: Jaws in 10 male beagle dogs were divided into four groups, and 36 dental implants were inserted into the jaws. In groups 1 and 2, experimental peri-implantitis was induced within 2 months after implant insertion. In group 1, surface decontamination of implants was achieved using air-flow and citric acid. In group 2, implants were sterilized with autoclave after air-flow and citric acid surface decontamination. Subsequently, these implants were inserted in contralateral jaws of the same dogs and a 3-month period was allowed for osseointegration. In group 3, the implants were removed from human jaws due to peri-implantitis and were inserted into dog jaws following surface cleaning protocol and sterilization with autoclave and a 3-month period was allowed for osseointegration. Group 4 was set as the control group. After the osseointegration period, all the animals were sacrificed. The degree of osseointegration in all groups was evaluated by evaluating the ISQ values and by using histomorphometric measurements. Results: Histological findings showed that bone-implant contact (BIC) percentage (mean ± SD) was 83.39% ± 6.37 in group 1, 79.93% ± 11.83 in group 2, 75.45% ± 9.09 in group 3, and 80.53 ± 5.22 in group 4. Moreover, the resonance frequency analysis (RFA) and ISQ values were similar in all four groups both before and after the implantation. Conclusions: The results of this experimental study indicated that there is no significant difference between new dental implants and re-used dental implants with regards to osseointegration around the implant.Publication Open Access Gastrointestinal tract metastasis of mandibular diffuse large B-cell lymphoma(2018-09-01) YÜCESOY, TÜRKER; KILIÇ, ERDEM; Ocak, Hakan; ALKAN, ALPER; DENİZ, KEMAL; YÜCESOY, TÜRKER; KILIÇ, ERDEM; ALKAN, ALPERNot only diffuse large B-cell lymphoma is a malignancy, but also is initially and orally diagnosed in early stages. However, it could be misdiagnosed with other oral pathologies. However yet, early diagnosis is still crucial for the prognosis, morbidity, and mortality in such cases. Additionally, whole-body scanning with positron emission tomography/computed tomography should be performed for diagnosis and treatment process.Publication Open Access Osseous changes in patients with medication-related osteonecrosis of the jaws(2018-01-01) GÖNEN, ZEYNEP BURÇİN; Asan, Canay Yillmaz; ZARARSIZ, GÖKMEN; KILIÇ, ERDEM; ALKAN, ALPER; KILIÇ, ERDEM; ALKAN, ALPERObjectives: Medication-related osteonecrosis of the jaw (MRONJ) is a severe side effect of antiresorptive agents. The aim of this study was to investigate the osseous changes in patients with MRONJ. Methods: Cone beam CT (CBCT) images of 25 patients with MRONJ and controls were retrospectively evaluated. Buccal, lingual, apical cortical bone thicknesses; buccal, lingual, apical intracortical and cancellous bone density; diameter of mental foramen and incisive canal, and width of mental foramen were measured. Results: Buccal and apical cortical bone thicknesses were increased; however intracortical radiodensity values decreased in the Study Group when compared with the Control Group (p = 0.007, p = 0.001). Narrowing of incisive canal was observed in patients with MRONJ (p = 0.000). Conclusions: Clinician should have awareness about narrowing of incisive canal, apical and buccal cortical bone thickening, decreasing in cancellous bone radiodensity, and the lingual cortex destruction in patients with MRONJ.Publication Metadata only Dentofasiyal Deformiteli Hastalarda Ortognatik Cerrahi Sonrası İskeletsel Relapsın Değerlendirilmesi / Evaluation of Skeletal Relapse After Orthognathic Surgery in Patients with Dentofacial Deformity(2019-04-28T00:00:00Z) YILDIRIM, COŞKUN; DEMİRBAŞ, AHMET EMİN; GÜL AMUK, NİSA; KÜTÜK, NÜKHET; KILIÇ, ERDEM; ALKAN, ALPER; KÜTÜK, NÜKHET; KILIÇ, ERDEM; ALKAN, ALPERPublication Metadata only Removal Of Osteosynthesis Plates After Orthognathic Surgery: A Retrospective Monocentric Study(2019-05-02T00:00:00Z) ÜLKER, ÖMER; DEMİRBAŞ, AHMET EMİN; KÜTÜK, NÜKHET; KILIÇ, ERDEM; ALKAN, ALPER; KÜTÜK, NÜKHET; KILIÇ, ERDEM; ALKAN, ALPERPublication Metadata only Intraoperative Complications in Orthognathic Surgery: Retrospective Evaluation of 250 Cases.(2017-05-23T00:00:00Z) DEMİRBAŞ, AHMET EMİN; ÜLKER, ÖMER; KÜTÜK, NÜKHET; KILIÇ, ERDEM; ALKAN, ALPER; KÜTÜK, NÜKHET; KILIÇ, ERDEM; ALKAN, ALPERPublication Metadata only Evaluation of Skeletal Relapse After Orthognathic Surgery in Patients with Dentofacial Deformity(2019-05-02T00:00:00Z) YILDIRIM, COŞKUN; DEMİRBAŞ, AHMET EMİN; GÜL AMUK, NİSA; KÜTÜK, NÜKHET; KILIÇ, ERDEM; ALKAN, ALPER; KÜTÜK, NÜKHET; KILIÇ, ERDEM; ALKAN, ALPERPublication Metadata only The changes of self-esteem, sensitivity to criticism, and social appearance anxiety in orthognathic surgery patients: A controlled study(2019-04-01) Agirnasligil, Mukerrem Ozge; Amuk, Nisa Gul; KILIÇ, ERDEM; KÜTÜK, NÜKHET; DEMİRBAŞ, AHMET EMİN; ALKAN, ALPER; KILIÇ, ERDEM; KÜTÜK, NÜKHET; ALKAN, ALPERObjectives: To evaluate the changes of psychologic parameters, such as self-esteem, sensitivity to criticism, and social appearance anxiety, in skeletal Class III patients undergoing orthognathic surgery and to compare the psychologic status of skeletal Class III patients with control subjects. Methods: The first group consisted of 60 patients with a mean age of 22.07 +/- 1.30 years who did not need orthognathic surgery. The second group comprised 45 patients with skeletal Class III malocclusion (mean age 21.40 +/- 2.02 years) who were evaluated in terms of psychologic changes from before to after surgery. A third group consisted of 50 Class III patients (mean age 20.09 +/- 2.59 years) who were evaluated before surgery and a different 50 Class III patients (mean age 22.15 +/- 2.03 years) who were investigated after surgery. The Rosenberg Self-Esteem Scale and the Social Appearance Anxiety Scale were used to evaluate psychologic parameters both before and after surgery. Analysis was carried out with the use of independent- and dependent-sample t tests, 1-way analysis of variance, and post hoc Tukey test. Results: Self-esteem of the patients with skeletal Class III malocclusion increased, and sensitivity to criticism and social appearance anxiety decreased significantly after the surgery (P < 0.001). In the patients with Class III malocclusion, self-esteem was significantly lower and social appearance anxiety significantly higher before orthognathic surgery than in the control group, and at the postoperative evaluation Class III patients had significantly higher self-esteem than the control group (P < 0.001). Conclusions: Through the improvement in facial appearance after surgery, patients- self-esteem increases and their sensitivity to criticism and social appearance anxiety decrease.