Person: ÇOBAN, GANİME
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Publication Metadata only Unusual Histopathological Findings in Appendectomy Specimens: A Retrospective Analysis of 2047 Cases.(2019-04-01) UNVER, NURCAN; COBAN, GANİME; ARıCı, DİLEK SEMA; BUYUKPıNARBASıLı, NUR; Gucin, ZÜHAL; MALYA, FATMA ÜMİT; ONARAN, OI; TOPALAN, K; ÜNVER, NURCAN; ÇOBAN, GANİME; ARICI, DILEK SEMA; BÜYÜKPINARBAŞILI, NUR; GÜCİN, ZÜHAL; MALYA, FATMA ÜMİTPublication Metadata only Anti-CD10 (56C6) expression in soft tissue sarcomas(2012-01-01T00:00:00Z) DENİZ, Kemal; Coban, Ganime; Okten, Turhan; ÇOBAN, GANİMECD10 is known to be expressed in certain types of leukemia, in lymphomas and also in various types of carcinoma. However, data regarding CD10 expression in soft tissue sarcomas is scarce. Two hundred and two retrospective soft tissue sarcoma specimens were evaluated for CD10 expression immunohistochemically. The clinical records of these patients were reviewed, and clinical data was obtained for all patients. Our results showed that 90 of the 202 cases were found to express CD10. 72% of malignant fibrous histiocytomas, 45% of fibrosarcomas, 34% of rhabdomyosarcomas, 50% of leiomyosarcomas, 22% of liposarcomas, 72% of malignant peripheral nerve sheath tumors, and 0% of the primitive neuroectodermal tumors were positive for CD10. Nearly half of the soft tissue sarcomas were found to express CD10. Stronger CD10 expression was found in high grade sarcomas. (C) 2012 Elsevier GmbH. All rights reserved.Publication Open Access Does ozone administration have a protective or therapeutic effect against radiotherapy-induced testicular injury?(2019-03-01) AYDOĞDU, İBRAHİM; İLBEY, YUSUF ÖZLEM; ÇOBAN, GANİME; EKİN, RAHMİ GÖKHAN; MİRAPOĞLU, SEMİH LÜTFİ; ÇAY, ALİ; KIZILTAN, HURİYE ŞENAY; EKİN, ZÜBEYDE YILDIRIM; SILAY, MESRUR SELÇUK; SEMERCİ, MEHMET BÜLENT; AYDOĞDU, İBRAHİM; ÇOBAN, GANİME; MİRAPOĞLU, SEMİH LÜTFİ; ÇAY, ALI; KIZILTAN, HURİYE ŞENAYObjective: We investigate the protective and therapeutic effects of ozone therapy (OT) in radiotherapy (RT)‑induced testicular damage. Methods: Thirty healthy adult male Wistar rats divided into five groups consisting of six animals each as follows: (1) Control (C), (2) RT, (3) OT, (4) OT + RT, and (5) RT + OT group. Histopathological findings, Johnsen scores, thiobarbituric acid‑reactive substances (TBARS), glutathione (GSH), superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx) levels were evaluated. Results: RT caused a significant decrease in testicular weight and Johnsen score compared to the control group. In addition, TBARS level was significantly higher, whereas GSH, SOD, catalase, and GPx levels were significantly lower in the RT group when compared to the control group. Pre and postRT OT significantly increased GSH, SOD, catalase, and GPx levels and decreased TBARS level. Furthermore, testicular weight and Johnsen score were increased with OT. Conclusions: The present study showed that OT is protective and therapeutic in radiation‑induced testicular damage. OT may be beneficial to the patients who underwent RT.Publication Metadata only Protective effect of dexpanthenol against nephrotoxic effect of amikacin: An experimental study(2017-05-01) Dogan, ELİF ECE; ERKOC, Reha; EKINCI, Iskender; HAMDARD, Jamshid; DONER, Baris; KARATOPRAK, CUMALİ; Coban, GANİME; Ozer, Omer Faruk; Kazancioglu, RÜMEYZA; DOĞAN, ELİF ECE; KARATOPRAK, CUMALİ; ÇOBAN, GANİME; ÖZER, ÖMER FARUK; KAZANCIOĞLU, RÜMEYZABackground: Amikacin has the largest spectrum among aminoglycosides, its nephrotoxic effect limits its utilization. Our purpose in this study is to review the protective effect of dexpanthenol against the nephrotoxic effect of amikacin, accompanied with histopathological and biochemical parameters.Publication Metadata only Investigation of Oxidative Stress Markers in the Pathogenesis of the Lung, Breast and Colon Cancer(2017-09-23T00:00:00Z) ÖZER, ÖMER FARUK; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİM; SELEK, ŞAHBETTİN; ÇOBAN, GANİME; TÜRK, HACI MEHMET; ÖZER, ÖMER FARUK; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİM; SELEK, ŞAHABETTİN; ÇOBAN, GANİME; TÜRK, HACI MEHMETPublication Metadata only Relationship between the poor glycemic control and risk factors, life style and complications.(2017-01-01T00:00:00Z) KAYAR, Yusuf; ILHAN, Aysegul; KAYAR, Nuket Bayram; Unver, NURCAN; Coban, GANİME; EKINCI, Iskender; HAMDARD, Jamsid; PAMUKCU, Ozgul; EROGLU, Hatice; ÜNVER, NURCAN; ÇOBAN, GANİMEIt has shown that the decrease of blood glucose levels in patient with diabetes mellitus decreases mortality and morbidity rates. Main purpose in diabetes is to achieve and prevent the glycemic control. We aimed to evaluate the relationship between poor glycemic control and metabolic parameters, individual life and complications. Seven hundred fifty seven patients with type II diabetes mellitus have evaluated with demographical characteristic, body mass index, abdominal circumferences, blood pressures, dietary compliances, physical exercise statuses and laboratory analysis; and the relationship of these parameteres were investigated. Poor glycemic control was found significantly associated with duration of diabetes, age of onset, family history, job status, educational status, antidiabetic drugs, body mass index, abdominal circumference, hypertension, lipid and fasting plasma glucose levels. There was a significant relationship between the glycemic control and dietary compliance, physical activity, self blood glucose monitoring and drug compliance. While there is a significant relationship between the poor glycemic control and nephropathy, retinopathy, neuropathy and cardiovascular diseases; no significant relationship was seen in the cerebrovascular diseases and arthropathy. We have pointed the relationship of glycemic control with sociodemographic, medical status, life style, lipid levels and complications. Better results can be obtained by eliminating the factors related to poor glycemic control.Publication Metadata only Radyoterapiye bağlı rat testisinde meydana gelen histolojik değişiklikler üzerine ozon tedavisinin koruyucu bir etkisi var mıdır?(2016-10-30) İLBEY, YUSUF ÖZLEM; AYDOĞDU, İBRAHİM; ÇOBAN, GANİME; EKİNCİ, RAHMİ GÖKHAN; MIRAPOGLU, S. L.; ÇAY, ALİ; KIZILTAN, HURİYE ŞENAY; SILAY, MESRUR SELÇUK; SEMERCİ, MEHMET BÜLENT; AYDOĞDU, İBRAHİM; ÇOBAN, GANİME; ÇAY, ALI; KIZILTAN, HURİYE ŞENAYPublication Metadata only Amikasinin nefrotoksik etkisine karşı dekspantenolun koruyucu etkisi: Deneysel bir çalışma(2014-10-26) DOĞAN, ELİF ECE; EKINCI, ISKENDER; HAMDARD, JAMSHID; DONER, BARIS; CIKRIKCIOGLU, MEHMET ALI; KARATOPRAK, CUMALİ; ÇOBAN, GANİME; ÖZER, ÖMER FARUK; KAZANCIOĞLU, RÜMEYZA; DOĞAN, ELİF ECE; KARATOPRAK, CUMALİ; ÇOBAN, GANİME; ÖZER, ÖMER FARUK; KAZANCIOĞLU, RÜMEYZAPublication Metadata only Can the use of reference pictures improve the interobserver variability on assessment of liver steatosis percentage: A digital platform based approach(2017-09-01) Turkmen, I. Cetinaslan; Cakir, A.; Capar, A.; Saka, B.; Kahraman, Z. S.; Erkan, S. Sengiz; Ozkan, Y.; Kepil, N.; Keser, S. Hallac; Gucin, Z.; Ceyran, B.; Coban, G.; Yilmaz, M. Segmen; Arici, S.; Dursun, N.; Dogusoy, G. Bulbul; Tuncel, D.; Ozguven, B. Yilmaz; Pasaoglu, E.; Kamali, G. Harman; Kirimlioglu, H.; Erdamar, S.; Yildiz, S.; Erdogan, N. Yildirim; Armutlu, A.; ÇOBAN, GANİME; ARICI, DILEK SEMAPublication Metadata only Effects of simultaneous integrated boost radiotherapy on kaposi’s sarcoma(2017-12-01) KIZILTAN, HURİYE ŞENAY; ÇOBAN, GANİME; KIRSEVER, ESRA; ERİŞ, ALİ HİKMET; ÖZSÜTÇÜ, NAZMİYE; MAYADAGLı, ALPASLAN; KIZILTAN, HURİYE ŞENAY; ÇOBAN, GANİME; ERİŞ, ALİ HİKMET; MAYADAĞLI, ALPASLAN