Person: YAMAÇ, AYLİN HATİCE
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Publication Metadata only SARS-CoV-2 Positivity, Stent Thrombosis, and 30-day Mortality in STEMI Patients Undergoing Mechanical Reperfusion(2022-10-01T00:00:00Z) De Luca, Giuseppe; Algowhary, Magdy; Uguz, Berat; Oliveira, Dinaldo C.; Ganyukov, Vladimir; Zimbakov, Zan; Cercek, Miha; Jensen, Lisette Okkels; Loh, Poay Huan; Calmac, Lucian; Ferrer, Gerard Roura; Quadros, Alexandre; Milewski, Marek; Di Uccio, Fortunato Scotto; von Birgelen, Clemens; Versaci, Francesco; Ten Berg, Jurrien; Casella, Gianni; Lung, Aaron Wong Sung; Kala, Petr; Gil, Jose Luis Diez; Carrillo, Xavier; Dirksen, Maurits; Becerra-Munoz, Victor M.; Lee, Michael Kang-Yin; Juzar, Dafsah Arifa; Joaquim, Rodrigo de Moura; De Simone, Ciro; Milicic, Davor; Davlouros, Periklis; Bakraceski, Nikola; Zilio, Filippo; Donazzan, Luca; Kraaijeveld, Adriaan; Galasso, Gennaro; Arpad, Lux; Marinucci, Lucia; Guiducci, Vincenzo; Menichelli, Maurizio; Scoccia, Alessandra; Yamac, Aylin Hatice; MERT, KADİR UĞUR; Rios, Xacobe Flores; Kovarnik, Tomas; Kidawa, Michal; Moreu, Jose; Flavien, Vincent; Fabris, Enrico; Martinez-Luengas, Inigo Lozano; Boccalatte, Marco; Ojeda, Francisco Bosa; Arellano-Serrano, Carlos; Caiazzo, Gianluca; Cirrincione, Giuseppe; Kao, Hsien-Li; Fores, Juan Sanchis; Vignali, Luigi; Pereira, Helder; Manzo-Silbermann, Stephane; Ordonez, Santiago; Ozkan, Alev Arat; Scheller, Bruno; Lehtola, Heidi; Teles, Rui; Mantis, Christos; Antti, Ylitalo; Silveira, Joao Antonio Brum; Bessonov, Ivan; Zoni, Rodrigo; Savonitto, Stefano; Kochiadakis, George; Alexopoulos, Dimitrios; Uribe, Carlos E.; Kanakakis, John; Faurie, Benjamin; Gabrielli, Gabriele; Barrios, Alejandro Gutierrez; Bachini, Juan Pablo; Rocha, Alex; Tam, Frankie Chor-Cheung; Rodriguez, Alfredo; Lukito, Antonia Anna; Bellemain-Appaix, Anne; Pessah, Gustavo; Cortese, Giuliana; Parodi, Guido; Burgadha, Mohammed Abed; Kedhi, Elvin; Lamelas, Pablo; Suryapranata, Harry; Nardin, Matteo; Verdoia, Monica; YAMAÇ, AYLİN HATİCESARS-Cov-2 has been suggested to promote thrombotic complications and higher mortality. The aim of the present study was to evaluate the impact of SARS-CoV-2 positivity on in-hospital outcome and 30-day mortality in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) enrolled in the International Survey on Acute Coronary Syndromes ST-segment elevation Myocardial Infarction (ISACS-STEMI COVID-19 registry. The 109 SARS-CoV-2 positive patients were compared with 2005 SARS-CoV-2 negative patients. Positive patients were older (P = .002), less often active smokers (P = .002), and hypercholesterolemic (P = .006), they presented more often later than 12 h (P = .037), more often to the hub and were more often in cardiogenic shock (P = .02), or requiring rescue percutaneous coronary intervention after failed thrombolysis (P < .0001). Lower postprocedural Thrombolysis in Myocardial Infarction 3 flow (P = .029) and more thrombectomy (P = .046) were observed. SARS-CoV-2 was associated with a significantly higher in-hospital mortality (25.7 vs 7%, adjusted Odds Ratio (OR) [95% Confidence Interval] = 3.2 [1.71-5.99], P < .001) in-hospital definite in-stent thrombosis (6.4 vs 1.1%, adjusted Odds Ratio [95% CI] = 6.26 [2.41-16.25], P < .001) and 30-day mortality (34.4 vs 8.5%, adjusted Hazard Ratio [95% CI] = 2.16 [1.45-3.23], P < .001), confirming that SARS-CoV-2 positivity is associated with impaired reperfusion, with negative prognostic consequences.Publication Open Access Impact of Smoking Status on Mortality in STEMI Patients Undergoing Mechanical Reperfusion for STEMI: Insights from the ISACS-STEMI COVID-19 Registry(2022-11-01) De Luca G.; Algowhary M.; Uguz B.; Oliveira D. C.; Ganyukov V.; Zimbakov Z.; Cercek M.; Jensen L. O.; Loh P. H.; Calmac L.; et al.; YAMAÇ, AYLİN HATİCEThe so-called \"smoking paradox\", conditioning lower mortality in smokers among STEMI patients, has seldom been addressed in the settings of modern primary PCI protocols. The ISACS-STEMI COVID-19 is a large-scale retrospective multicenter registry addressing in-hospital mortality, reperfusion, and 30-day mortality among primary PCI patients in the era of the COVID-19 pandemic. Among the 16,083 STEMI patients, 6819 (42.3%) patients were active smokers, 2099 (13.1%) previous smokers, and 7165 (44.6%) non-smokers. Despite the impaired preprocedural recanalization (p < 0.001), active smokers had a significantly better postprocedural TIMI flow compared with non-smokers (p < 0.001); this was confirmed after adjustment for all baseline and procedural confounders, and the propensity score. Active smokers had a significantly lower in-hospital (p < 0.001) and 30-day (p < 0.001) mortality compared with non-smokers and previous smokers; this was confirmed after adjustment for all baseline and procedural confounders, and the propensity score. In conclusion, in our population, active smoking was significantly associated with improved epicardial recanalization and lower in-hospital and 30-day mortality compared with previous and non-smoking history.Publication Open Access Outcomes in Coronary No Reflow Phenomenon Patients and the Relationship between Kidney Injury Molecule-1 and Coronary No-Reflow Phenomenon(2021-02-01T00:00:00Z) Huyut, Mustafa Ahmet; YAMAÇ, AYLİN HATİCE; YAMAÇ, AYLİN HATİCEBackground: Coronary no-reflow phenomenon (CNP) is associated with an increased risk of major cardiovascular adverse events (MACE).Publication Metadata only EuroSCORE II and STS score as a predictor of acute kidney injury following transcatheter aortic valve replacement: two birds with one stone?(2020-12-06T00:00:00Z) BAKSHALİYEV, NİJAD; KARAÇÖP, ERDEM; ENHOŞ, ASİM; YAMAÇ, AYLİN HATİCE; KAHRAMAN AY, NURAY; ÖZDEMİR, RAMAZAN; KARAÇÖP, ERDEM; ENHOŞ, ASIM; YAMAÇ, AYLİN HATİCE; KAHRAMAN AY, NURAY; ÖZDEMİR, RAMAZAN