Person: ÖZDEMİR, MEHMET HAKAN
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Publication Metadata only Evaluation of xenon, light-emitting diode (LED) and halogen light toxicity on cultured retinal pigment epithelial cells(2018-11-01) SEZER, TAHA; ALTINIŞIK, MUHAMMED; GÜLER, ERAY METİN; Kocyigit, Abdurrahim; ÖZDEMİR, MEHMET HAKAN; KOYTAK, İBRAHİM ARİF; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİM; ÖZDEMİR, MEHMET HAKAN; KOYTAK, İBRAHİM ARİFObjective: To compare the possible toxic effects of three light sources used in vitreoretinal endoillumination systems; halogen, xenon, and light-emitting diode (LED) on retinal pigment epithelium (RPE) cell cultures, after two different exposure times. Material and methods: ARPE-19 human RPE cell cultures were exposed to halogen, xenon, and LED light sources at a distance of 1.5 cm for 30 and 60 min with equal lumen output levels. Cells in the control group were not exposed. RPE cell cultures were compared in terms of cell viability, DNA damage, apoptosis rate, and IL-1 ss, IL-6, and TNF- alpha levels. Results: The halogen light group showed significantly more DNA damage, higher TNF-alpha, IL-1 beta, and IL-6 levels, and lower viable cell count at 30 min compared to the control group. The rates of early and late apoptosis were also significantly higher at 60 min. There were no statistically significant differences in any of the parameters between the xenon and LED light sources and the control group at 30 or 60 min. Conclusion: New generation lights, xenon, and LED, seem to be safe in terms of RPE cells. Halogen light may cause toxic effects on RPE cells when used for a long time with maximal power output.Publication Metadata only SPONTANEOUS REGRESSION OF SEROUS RETINAL DETACHMENT ASSOCIATED WITH CIRCUMSCRIBED CHOROIDAL HEMANGIOMA AFTER CHILDBIRTH.(2017-01-01) Sayman, Muslubas; ARF, S; Hocaoglu, M; Ozdemir, HÜSEYİN; Karacorlu, M; ÖZDEMİR, MEHMET HAKANPublication Metadata only Microperimetric Changes After Photodynamic Therapy for Central Serous Chorioretinopathy(2011-02-01) SENTURK, Fevzi; KARACORLU, Murat; OZDEMIR, Hakan; KARACORLU, Serra Arf; Uysal, Omer; ÖZDEMİR, MEHMET HAKAN; UYSAL, ÖMERPURPOSE: To evaluate the effect of half-dose verteporfin photodynamic therapy (PDT) on macular function in cases of central serous chorioretinopathy (CSC).Publication Metadata only Regression of Serous Macular Detachment After Intravitreal Dexamethasone Implant in Patients with Diabetic Macular Edema.(2019-10-24) Ozdemir, MH; Ekinci, C; Kirik, F; Koytak, A; ÖZDEMİR, MEHMET HAKAN; ELBAY, AHMET; KIRIK, FURKAN; EKİNCİ, CANSU; KOYTAK, İBRAHİM ARİFPublication Metadata only MICROPERIMETRIC CHANGES AFTER INTRAVITREAL TRIAMCINOLONE ACETONIDE INJECTION FOR MACULAR EDEMA DUE TO CENTRAL RETINAL VEIN OCCLUSION(2010-09-01T00:00:00Z) SENTURK, Fevzi; OZDEMIR, Hakan; KARACORLU, Murat; KARACORLU, Serra Arf; Uysal, Omer; ÖZDEMİR, MEHMET HAKAN; UYSAL, ÖMERPurpose: The purpose of this study was to evaluate the effect of intravitreal triamcinolone acetonide on macular function in cases of macular edema because of central retinal vein occlusion.Publication Metadata only The effect of allergic rhinitis with positive skin prick test on choroidal thickness.(2017-06-01) OZTURAN, ORHAN; OZDEMIR, MEHMET HAKAN; YENIGUN, A; Dogan, REMZİ; ELBAY, AHMET; YENİGÜN, ALPER; ELBAY, AHMET; DOĞAN, REMZI; ÖZTURAN, ORHAN; ÖZDEMİR, MEHMET HAKANPublication Metadata only Macular Burns from Nonmedical Lasers(2016-06-01T00:00:00Z) Muslubas, Isil Sayman; Hocaoglu, M; Arf , S; ÖZDEMİR, MEHMET HAKAN; Karacorlu, M; ÖZDEMİR, MEHMET HAKANLaser devices are widely used for medical, military, industrial and entertainment purposes. This extensive and unregulated use of lasers can cause a variety of maculopathies that can result in permanent vision loss. Uncontrolled and inappropriate use of laser instruments should be prevented with strict rules. We strongly emphasize the importance of changing the general misperception that lasers are safe to use for entertainment purposes. In this study we aim to report the clinical features of three patients with a history of maculopathy caused by exposure to laser light in an entertainment venue.Publication Metadata only Microperimetric changes after intravitreal bevacizumab injection for exudative age-related macular degeneration(2012-02-01) OZDEMIR, Hakan; KARACORLU, Murat; SENTURK, Fevzi; KARACORLU, Serra Arf; Uysal, Omer; ÖZDEMİR, MEHMET HAKAN; UYSAL, ÖMERPurpose: To evaluate the effect of intravitreal bevacizumab on macular function in the cases of exudative age-related macular degeneration (AMD).Publication Metadata only Visual impairment in pseudoxanthoma elasticum: a survey of 53 patients from Turkey(2016-09-01) HOCAOGLU, Mumin; KARACORLU, Murat; MUSLUBAS, Isil Sayman; ARF, Serra; OZDEMIR, Hakan; Uysal, Omer; ÖZDEMİR, MEHMET HAKAN; UYSAL, ÖMERPurpose: To estimate the age at onset and severity of ophthalmologic aspects of pseudoxanthoma elasticum (PXE).Publication Metadata only LONG-TERM OUTCOMES OF RADIAL OPTIC NEUROTOMY FOR MANAGEMENT OF OPTIC DISK PIT MACULOPATHY(2016-12-01) KARACORLU, Murat; MUSLUBAS, Isil Sayman; HOCAOGLU, Mumin; OZDEMIR, Hakan; ARF, Serra; Uysal, Omer; ÖZDEMİR, MEHMET HAKAN; UYSAL, ÖMERPurpose: To evaluate the long-term outcomes of radial optic neurotomy (RON) in patients with optic disk pit maculopathy and to compare the functional and anatomical outcomes of pars plana vitrectomy (PPV) with temporal side single RON versus PPV without RON.