Person: ÖZDEMİR, MEHMET HAKAN
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Publication Metadata only Acute Phototoxic Retinopathy due to Infrared Heater(2020-09-01T00:00:00Z) Kırık, Furkan; Çevik, Neslihan; Bayraktar, Havvanur; Özdemir, Mehmet Hakan; KIRIK, FURKAN; BAYRAKTAR, HAVVANUR; ÖZDEMİR, MEHMET HAKANPublication Metadata only Relation of anatomy with function following the surgical treatment of idiopathic epiretinal membrane: a multicenter retrospective study(2020-11-01T00:00:00Z) ÖZDEK, ŞENGÜL; Ozdemir Zeydanli, Ece; Karabas, Levent; Teke, Mehmet Yasin; Yilmaz, Gursel; Citirik, Mehmet; Kocak, Nilufer; Durukan, Hakan; ÖZDEMİR, MEHMET HAKANPurpose To investigate the prognostic factors associated with functional and anatomical outcomes and to assess the longitudinal course of visual acuity and retinal morphology after vitreoretinal surgery for idiopathic epiretinal membrane (ERM). Methods This multicenter, retrospective study included a total of 634 eyes who underwent surgery for idiopathic ERM in 22 academic centers nationwide in Turkey. Data on best-corrected visual acuity (BCVA) and optical coherence tomography features (central foveal thickness (CFT), ERM and foveal contour morphology, ellipsoid zone (EZ) integrity) were collected and compared at baseline, 6-month, 12-month, and 24-month follow-ups. Prognostic factors for functional (having >= 20/25 Snellen BCVA) and anatomical (having normal/shallow foveal contour) recoveries after surgery were investigated by means of multivariate regression analyses. A cutoff value of preoperative BCVA optimizing functional recovery was calculated using receiver operating characteristic curve analysis. Results At a median follow-up of 24 months, 37.4% of the eyes achieved >= 20/25 BCVA and 54% regained normal or shallow foveal contour. Functional recovery was more likely in eyes with better baseline BCVA and intact EZ (R-2 = 0.356, p < 0.001). The cutoff baseline BCVA value for good visual prognosis was 0.35 logarithm of the minimum angle of resolution (Snellen 20/44) (sensitivity 60%, specificity 85%, p < 0.001). Anatomical recovery was negatively associated with advanced age, higher baseline CFT, foveal herniation-type ERM morphology, and internal limiting membrane (ILM) peeling (R-2 = 0.225, p < 0.001). The negative effect of ILM peeling on anatomical recovery was not significant after the first postoperative year (p = 0.05). Mean BCVA values and foveal morphology progressively improved at each visit. Cases with convex baseline foveal contour continued to change towards normal foveal depression over 24 months of follow-up, which took longer than the eyes with shallow/flat contoured cases. One-third of eyes with severe baseline EZ defects showed recovery at follow-up and achieved significantly greater visual acuity gains than the remaining eyes with persistent defects (p < 0.001). Conclusions Functional and anatomical restoration of the eyes appears to be a slow process after ERM surgery. This process may take much longer in eyes with worse foveal morphology at baseline. Although photoreceptor disruption may be reversible in some eyes, full functional recovery is unlikely when it persists.Publication Metadata only Spectral domain optical coherence tomography classification of diabetic macular edema: a new proposal to clinical practice.(2020-03-09T00:00:00Z) Arf, S; Sayman, Muslubas; Hocaoglu, M; Ersoz, Mg; Ozdemir, H; Karacorlu, M; ÖZDEMİR, MEHMET HAKANPublication Metadata only The relationship between preoperative anterior chamber parameters and postoperative refractive error in cataract surgery(2020-09-01T00:00:00Z) Koytak, İbrahim Arif; Kırık, Furkan; Özdemir, Mehmet Hakan; KIRIK, FURKAN; KOYTAK, İBRAHİM ARİF; ÖZDEMİR, MEHMET HAKANPurpose: Postoperative refraction has become important with improvements in cataract surgery. In this study, our aim was to investigate the effects of phacoemulsifi cation-intraocular lens (P-IOL) implantation on anterior chamber angle (ACA), anterior chamber volume (ACV), anterior chamber depth (ACD), and to assess relationship between these parameters and axial length (AL) and postoperative refractive error. Materials and Methods: We retrospectively reviewed data from 231 patients who underwent P-IOL implantation between January 2012 and June 2014. Scheimpfl ug imaging system was used for the determination of ACA, ACV and ACD values at preoperative and postoperative month 3. Partial coherence laser interferometry was used for preoperative AL, target postoperative refractive error and IOL power calculated by SRK-T formula. Spherical equivalent (SE=spherical error plus cylindrical error /2) at postoperative month 3 was recorded. Postoperative refractive error was calculated as mean error (ME=postoperative refraction-target refraction) and mean absolute error (MAE=absolute of ME). Data obtained at preoperative period and postoperative month 3 were compared. Results: Preoperative ACA, ACV, ACD were 30,2 ±12,1°, 130,7 ±41,2 mm³, 2,6 ±0,4 mm while postoperative ACA, ACV, ACD were 42,7 ±5,8°, 172,1 ±28,2 mm³, 4,1 ±0,7 mm respectively. Anterior chamber parameters were increased after P-IOL implantation, as all differences being statistically signifi cant (p=0.001). No signifi cant correlation was found between ME and ACA, ACV, ACD, AL. Again, no signifi cant correlation was found between MAE and ACA, ACV, ACD. Only a weak correlation was found between MAE and AL. Conclusion: Anterior chamber parameters measurements after P-IOL are signifi cantly increased compared to preoperative values. There was no signifi cant correlation between preoperative ACA, ACV, ACD and AL, and postoperative refractive error.Publication Metadata only Response to commentary -Retinal nerve fiber layer analysis in unaffected first-degree relatives of schizophrenia patients-.(2020-04-18T00:00:00Z) Ozdemir, MH; Kurtulmus, A; Elbay, AHMET; ELBAY, AHMET; ÖZDEMİR, MEHMET HAKANPublication Metadata only Fluorescein angiography as a primary guide for reduced-fluence photodynamic therapy for the treatment of chronic central serous chorioretinopathy.(2020-04-09T00:00:00Z) Koytak, A; Bayraktar, H; Ozdemir, H; KOYTAK, İBRAHİM ARİF; ÖZDEMİR, MEHMET HAKANPublication Metadata only An investigation of retinal layer thicknesses in unaffected first-degree relatives of schizophrenia patients.(2020-01-14T00:00:00Z) Kurtulmus, A; Parlakkaya, FB; Kilicarslan, T; Ozdemir, MEHMET HAKAN; Kirpinar, I; ELBAY, AHMET; ÖZDEMİR, MEHMET HAKANPublication Metadata only Regional analysis of segmented-macular structure in patients with myopic anisometropia(2021-06-01T00:00:00Z) KIRIK, FURKAN; EKİNCİ, CANSU; AKBULUT, ERSİN; BAYRAKTAR, HAVVANUR; Ozdemir, Hakan; KIRIK, FURKAN; EKİNCİ, CANSU; AKBULUT, ERSİN; BAYRAKTAR, HAVVANUR; ÖZDEMİR, MEHMET HAKANPurpose To compare intraretinal layers between the eyes in patients with myopic anisometropia, and evaluate the relationship between the layers with spherical equivalent (SE) and axial length (AL). Methods In this retrospective study, the more myopic (MM) and fellow (F) eyes of 41 patients with myopic anisometropia, and 38 emmetropic (+/- 0.50 diopter) control (C) eyes were inclueded. Intraretinal layer segmentation was performed by optical coherence tomography. Global volumes of retinal layers and their thicknesses in nine macular regions were compared. Correlation analysis was used to determine the relationship with SE and AL in each layer. Results Total retinal, ganglion cell (GCL), inner nuclear (INL), and outer plexiform (OPL) layer volumes in MM eyes were less than in C eyes, while INL and OPL were less than in F eyes. There was no difference in the fovea, except for the retinal pigment epithelium. In MM eyes, only INL and OPL were thin in at least one perifoveal and parafoveal quadrant compared to F eyes. Only INL and OPL thicknesses were significantly correlated with both SE and AL in all perifoveal quadrants. In contrast to the thinning found in MM eyes, the only layer in which thickening was detected to compare to C eye was nerve fiber layer (NFL), which correlated positively with SE and negatively with AL. Conclusion While the fovea is less affected by myopia, thinning becomes remarkable in the perifoveal quadrants. Despite thinning in many layers, especially INL and OPL, NFL thickening may be seen due to myopia.Publication Metadata only Expert recommendations for the management of diabetic macular edema with intravitreal dexamethasone implant: A Turkish Delphi study(2022-08-01T00:00:00Z) Batioglu, Figen; YANIK ODABAŞ, ÖZGE; SAATCİ, ALİ OSMAN; Eldem, Bora; AKKIN, CEZMİ; AFRASHİ, FİLİZ; Ozdemir, Hakan; MENTEŞ, JALE; Gungor, Kivanc; KARABAŞ, VEYSEL LEVENT; Karacorlu, Murat; DEMİRCAN, AYŞE NİHAL; Kocak, Nilufer; Kir, Nur; Unlu, Nurten; Avci, Remzi; Arvas, Sema; Dundar, Sema Oruc; KADAYIFÇILAR, SİBEL; KAYNAK, SÜLEYMAN; ÖZDEK, ŞENGÜL; Ovali, Tunc; ÖZDEMİR, MEHMET HAKANPurpose To provide consensus on the clinical use of intravitreal dexamethasone (DEX) implant for the treatment of diabetic macular edema (DME) in Turkey. Methods A panel of 22 retina experts prepared 77 statements of recommendation, and 80 retinal specialists practicing in Turkey were chosen to vote either in support or against each one. A Delphi-based method was used through which the ophthalmologists were able to view all of the results anonymously after two rounds and modify their subsequent answers. The survey was conducted via a mini website, and statements without consensus were resent to the specialists with the latest vote results a week later. Results A total of 72 ophthalmologists answered the first and second round questions. After the first stage, consensus was achieved on 55 of the statements, leaving 22 without agreement. After the second stage, consensus was reached on 11 of the remaining statements. Strong consensus was achieved on statements regarding the etiopathogenesis of DME and the first-line indications and safety of the DEX implant procedure. The panel recommended the use of DEX implant for patients with an arterial thromboembolic event in the last three months and also agreed that pro re nata DEX implant treatment not only provides better outcomes for DME patients but also reduces the treatment burden for those who could not receive an adequate number of anti-vascular endothelial growth factor (VEGF) injections. Conclusion This study provides clinical consensus and recommendations about the use of DEX implant in the clinical practice of DME management in Turkey.