Person: ÖZDEMİR, MEHMET HAKAN
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Publication Metadata only Diyabetik Retinopati ve Makulopati(2021-05-01T00:00:00Z) Özdemir, Mehmet Hakan; Kırık, Furkan; ÖZDEMİR, MEHMET HAKAN; KIRIK, FURKANOptik Koherens Tomografi (OKT), retinanın yüksek çözünürlükte görüntülenmesine olanak sağlayan, girişimsel olmayan bir görüntüleme yöntemidir. Retinal patolojiler hakkındaki kantitatif ve kalitatif verileri diğer görüntüleme yöntemlerinden daha hızlı elde etmeye olanak sağlaması nedeniyle diyabetik retinopatinin (DR) tanı ve takibinde OKT’den giderek daha fazla yararlanılmaktadır. OKT’nin oftalmolojik, özellikle de DR-de, kullanımıyla birlikte birçok retinal lezyon daha ayrıntılı tanımlanmaya başlandı ve hatta bazı retinal değişiklikler ilk defa OKT ile gösterildi. Daha önce yapılan araştırmalar sonucunda, DR’ye bağlı tespit edilen bir takım patolojik bulguların tedavi yanıtı üzerine ve nihai görme keskinliği üzerine öngörülebilir sonuçlar verdiği tespit edildi ve bu bulgulara prognostik değer biçilerek çeşitli biyobelirteçler tanımlandı. Günümüzde artık DR’ye ait çeşitli komplikasyonların tanısında sıklıkla faydalandığımız OKT görüntülerinin hastaya ait klinik bulgular ile birlikte değerlendirilmesi, hem uygulanacak tedavinin erkenden belirlenebilmesi hem de hastalık prognozunun öngörülebilmesi açısından faydalı olacaktır.Publication Metadata only Evaluation of xenon, light-emitting diode (LED) and halogen light toxicity on cultured retinal pigment epithelial cells(2018-11-01) SEZER, TAHA; ALTINIŞIK, MUHAMMED; GÜLER, ERAY METİN; Kocyigit, Abdurrahim; ÖZDEMİR, MEHMET HAKAN; KOYTAK, İBRAHİM ARİF; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİM; ÖZDEMİR, MEHMET HAKAN; KOYTAK, İBRAHİM ARİFObjective: To compare the possible toxic effects of three light sources used in vitreoretinal endoillumination systems; halogen, xenon, and light-emitting diode (LED) on retinal pigment epithelium (RPE) cell cultures, after two different exposure times. Material and methods: ARPE-19 human RPE cell cultures were exposed to halogen, xenon, and LED light sources at a distance of 1.5 cm for 30 and 60 min with equal lumen output levels. Cells in the control group were not exposed. RPE cell cultures were compared in terms of cell viability, DNA damage, apoptosis rate, and IL-1 ss, IL-6, and TNF- alpha levels. Results: The halogen light group showed significantly more DNA damage, higher TNF-alpha, IL-1 beta, and IL-6 levels, and lower viable cell count at 30 min compared to the control group. The rates of early and late apoptosis were also significantly higher at 60 min. There were no statistically significant differences in any of the parameters between the xenon and LED light sources and the control group at 30 or 60 min. Conclusion: New generation lights, xenon, and LED, seem to be safe in terms of RPE cells. Halogen light may cause toxic effects on RPE cells when used for a long time with maximal power output.Publication Metadata only SPONTANEOUS REGRESSION OF SEROUS RETINAL DETACHMENT ASSOCIATED WITH CIRCUMSCRIBED CHOROIDAL HEMANGIOMA AFTER CHILDBIRTH.(2017-01-01) Sayman, Muslubas; ARF, S; Hocaoglu, M; Ozdemir, HÜSEYİN; Karacorlu, M; ÖZDEMİR, MEHMET HAKANPublication Metadata only Microperimetric Changes After Photodynamic Therapy for Central Serous Chorioretinopathy(2011-02-01) SENTURK, Fevzi; KARACORLU, Murat; OZDEMIR, Hakan; KARACORLU, Serra Arf; Uysal, Omer; ÖZDEMİR, MEHMET HAKAN; UYSAL, ÖMERPURPOSE: To evaluate the effect of half-dose verteporfin photodynamic therapy (PDT) on macular function in cases of central serous chorioretinopathy (CSC).Publication Metadata only Regression of Serous Macular Detachment After Intravitreal Dexamethasone Implant in Patients with Diabetic Macular Edema.(2019-10-24) Ozdemir, MH; Ekinci, C; Kirik, F; Koytak, A; ÖZDEMİR, MEHMET HAKAN; ELBAY, AHMET; KIRIK, FURKAN; EKİNCİ, CANSU; KOYTAK, İBRAHİM ARİFPublication Metadata only MICROPERIMETRIC CHANGES AFTER INTRAVITREAL TRIAMCINOLONE ACETONIDE INJECTION FOR MACULAR EDEMA DUE TO CENTRAL RETINAL VEIN OCCLUSION(2010-09-01T00:00:00Z) SENTURK, Fevzi; OZDEMIR, Hakan; KARACORLU, Murat; KARACORLU, Serra Arf; Uysal, Omer; ÖZDEMİR, MEHMET HAKAN; UYSAL, ÖMERPurpose: The purpose of this study was to evaluate the effect of intravitreal triamcinolone acetonide on macular function in cases of macular edema because of central retinal vein occlusion.Publication Metadata only The effect of allergic rhinitis with positive skin prick test on choroidal thickness.(2017-06-01) OZTURAN, ORHAN; OZDEMIR, MEHMET HAKAN; YENIGUN, A; Dogan, REMZİ; ELBAY, AHMET; YENİGÜN, ALPER; ELBAY, AHMET; DOĞAN, REMZI; ÖZTURAN, ORHAN; ÖZDEMİR, MEHMET HAKANPublication Metadata only Ophthalmological Perspective on Pediatric Ear, Nose, and Throat Infections(Springer, London/Berlin , 2021-11-01) Kırık F.; Özdemir M. H.; KIRIK, FURKAN; ÖZDEMİR, MEHMET HAKANThe majority of the tissues and organs that fall into the area of expertise of ear, nose and throat (ENT) specialists are adjacent to the orbit, and therefore to the globe. As a result of this contiguity, ENT diseases can spread to the orbit and present with various orbital complications. While these complications can be mild, they can also manifest as severe morbidities that lead to permanent loss of vision. In addition, ENT diseases can also spread to the cranium as well as the orbit, and lead to severe intracranial complications that may result in mortality. Such intracranial complications may also manifest with findings in an ophthalmological examination, as many cranial nerves (CNs) are also associated with the orbital structures. This is why ENT specialists commonly encounter ophthalmological findings as a result of both the orbital and cranial complications of infectious ENT diseases. In addition, ophthalmological examination findings are useful for diagnosis, as some infectious agents can cause a common infection both in the ocular and head-neck region.Publication Metadata only İleri Derecede Myelinli Sinir Lifi Bulunan Bir Olguda Koroidin Optik Koherens Tomografiile Değerlendirilmesi(2015-11-08) ELBAY, AHMET; Melikov, Arif; Sezer, Taha; ÖZDEMİR, MEHMET HAKAN; ELBAY, AHMET; ÖZDEMİR, MEHMET HAKANPublication Metadata only Siliyoretinal arter varlığı olan santral retinal arter oklüzyonunda maküla ödemi ve foveal dekolman(2015-11-08) Hamzayev, İgbal; MELİKOV, Arif; ELBAY, AHMET; ÖZDEMİR, MEHMET HAKAN; HAMZAYEV, IGBAL; ELBAY, AHMET; ÖZDEMİR, MEHMET HAKAN