Person:
ŞEKER, MESUT

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MESUT
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ŞEKER
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  • PublicationMetadata only
    Important factors affecting adjuvant treatment decision in stage IA breast cancer patients in Turkey
    (2014-01-01T00:00:00Z) OVEN USTAALIOGLU, Bala B.; Bilici, Ahmet; YILMAZ, Burçak E.; ALIUSTAOGLU, Mehmet; Seker, MESUT; VARDAR, Fugen; Gümüş, Mahmut; ŞEKER, MESUT
  • PublicationOpen Access
    Prognostic Significance of Metastatic Lymph Node Ratio in Patients with pN3 Gastric Cancer Who Underwent Curative Gastrectomy.
    (2019-01-01T00:00:00Z) Bilici, A; Selcukbiricik, F; Seker, MESUT; Oven, BB; Olmez, OF; Yildiz, O; Olmuscelik, O; Hamdard, J; Acikgoz, O; Cakir, A; Kapran, Y; Balik, E; Oncel, M; ŞEKER, MESUT
    Background: Lymph node involvement is an important prognostic factor in patients with gastric cancer. The aim of this study was to determine the prognostic significance of metastatic lymph node ratio (MLNR) and compare it to the number of lymph node metastasis in pN3 gastric cancer. Methods: We retrospectively analyzed 207 patients with pN3 gastric cancer who had undergone radical gastrectomy. Prognostic factors and MLNR were evaluated by univariate and multivariate analysis. Results: An MLNR of 0.75 was found to be the best cut-off value to determine the prognosis of patients with pN3 gastric cancer (p = 0.001). The MLNR was significantly higher in patients with large-sized and undifferentiated tumors, vascular, lymphatic and perineural invasion, and total gastrectomy. In multivariate analysis, MLNR (p = 0.041), tumor differentiation (p = 0.046), and vascular invasion (p = 0.012) were found to be independent prognostic factors for disease-free survival, while both MLNR (p < 0.001) and pN stage (p = 0.002) were independent prognostic indicators, as was tumor size, for overall survival. There was significant difference with respect to the recurrence patterns between MLNR groups. Lymph node and peritoneal recurrences were significantly higher in patients with MLNR > 0.75 compared to the MLNR < 0.75 group (p < 0.05). However, recurrence patterns were similar between pN3a and pN3b. Conclusion: Our results showed that MLNR was a useful indicator to determine the prognosis and recurrence patterns of patients with radically resected gastric cancer. Moreover, MLNR is a beneficial and reliable technique for evaluating lymph node metastasis.
  • PublicationMetadata only
    Clinical and pathologic features of patients with rare ovarian tumors: multi-center review of 167 patients by the anatolian society of medical oncology.
    (2014-01-01T00:00:00Z) BILICI, A; INANC, M; ULAS, A; AKMAN, T; Seker, MESUT; BABACAN, NA; INAL, A; BAL, O; KORAL, L; SEVINC, A; TUFAN, G; ELKIRAN, ET; USTAALIOĞLU, BB; YAVUZSEN, T; ALKIS, N; OZKAN, M; GUMUS, M; ŞEKER, MESUT