Person: KESKİN, YAŞAR
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Publication Open Access Beyond expectations: disease duration and psychological burden in psoriatic arthritis.(2023-07-07) Kılıç G.; Kılıç E.; Tekeoğlu İ.; Sargın B.; Cengiz G.; Balta N. C.; Alkan H.; Kasman S. A.; Şahin N.; Orhan K.; Gezer İ. A.; Keskin D.; Mülkoğlu C.; Reşorlu H.; Ataman Ş.; Bal A.; Duruöz M. T.; Küçükakkaş O.; Şen N.; Toprak M.; Yurdakul O. V.; Melikoğlu M. A.; Ayhan F. F.; Baykul M.; Bodur H.; Çalış M.; Çapkın E.; Devrimsel G.; Hizmetli S.; Kamanlı A.; Keskin Y.; Ecesoy H.; Kutluk Ö.; Şendur Ö. F.; Tolu S.; Tuncer T.; Nas K.; YURDAKUL, OZAN VOLKAN; KÜÇÜKAKKAŞ, OKAN; KESKİN, YAŞARThis study aims to investigate the relationship between disease duration and psychological burden in PsA and to identify the risk factors associated with psychological distress. Patients with PsA who met CASPAR classifcation criteria enrolled by Turkish League Against Rheumatism (TLAR)-Network. Patients were categorized into three groups based on disease duration: early stage (<5 years), middle stage (≥5,<10 years), and late stage (≥10 years). All patients underwent clinical and laboratory assessment using standardized protocol and case report forms. The associations between psychological variables and clinical parameters were assessed by a multivariate analysis. Of the 1113 patients with PsA (63.9% female), 564 (%50.7) had high risk for depression and 263 (%23.6) for anxiety. The risk of psychological burden was similar across all PsA groups, and patients with a higher risk of depression and anxiety also experienced greater disease activity, poorer quality of life, and physical disability. Multivariate logistic regression revealed that female gender (OR=1.52), PsAQoL (OR=1.13), HAQ (OR=1.99), FiRST score (OR=1.14), unemployment/retired (OR=1.48) and PASI head score (OR=1.41) were factors that infuenced the risk of depression, whereas the current or past enthesitis (OR=1.45), PsAQoL (OR=1.19), and FiRST score (OR=1.26) were factors that infuenced the risk of anxiety. PsA patients can experience a comparable level of psychological burden throughout the course of their disease. Several socio-demographic and disease-related factors may contribute to mental disorders in PsA. In the present era of personalized treatment for PsA, evaluating psychiatric distress can guide tailored interventions that improve overall well-being and reduce disease burden.Publication Metadata only Disk materyallerindeki oksidatif stress disk herniasyonunda önemli bir faktör müdür?(2016-03-27) Taşpınar, Özgür; AYDIN, TEOMAN; SEYİTHANOĞLU, MEHMET HAKAN; KESKİN, YAŞAR; Kepekçi, Müge; GÜLER, ERAY METİN; KİTİŞ, SERKAN; DÜNDAR, TOLGA TURAN; AYDIN, TEOMAN; SEYİTHANOĞLU, MEHMET HAKAN; KESKİN, YAŞAR; GÜLER, ERAY METİN; KİTİŞ, SERKAN; DÜNDAR, TOLGA TURANPublication Metadata only The effect of fibromyalgia on bone mineral density in patients with hypothyroidism(2019-05-01T00:00:00Z) TAŞPINAR, ÖZGÜR; KESKİN, YAŞAR; kiziltan, huriye; ÇAMLI, AHMET ADİL; URKMEZ, BERNA; mutluer, ahmet serdar; AYDIN, TEOMAN; eriş, ali h; KESKİN, YAŞAR; AYDIN, TEOMAN; ÇAMLI, AHMET ADİLPublication Open Access The impact of COVID-19 on familial Mediterranean fever: a nationwide study(2021-05-25T00:00:00Z) Günendi, Zafer; Yurdakul, Fatma Gül; Bodur, Hatice; Cengiz, Ahmet Kıvanç; Uçar, Ülkü; Çay, Hasan Fatih; Şen, Nesrin; Keskin, Yaşar; Gürer, Gülcan; Melikoğlu, Meltem Alkan; Altıntaş, Duygu; Deveci, Hülya; Baykul, Merve; Nas, Kemal; Çevik, Remzi; Karahan, Ali Yavuz; Toprak, Murat; Ketenci, Sertaç; Nayimoğlu, Mehmet; Sezer, İlhan; Demir, Ali Nail; Ecesoy, Hilal; Duruöz, Mehmet Tuncay; Yurdakul, Ozan Volkan; Sarıfakıoğlu, Ayşe Banu; Ataman, Şebnem; KESKİN, YAŞAR; YURDAKUL, OZAN VOLKANThe study aimed to evaluate the impact of the coronavirus disease 2019 (COVID-19) in patients with familial Mediterranean fever (FMF) and to assess the relationships between FMF characteristics and severe COVID-19 outcomes such as hospitalization. The study was planned within a national network of 21 different centers. Demographics, FMF-related clinical and genetic characteristics, and COVID-19 outcomes were obtained. A total of 822 patients with FMF (mean age of 36 years) were included in the study. Fifty-nine of them (7%) had a COVID-19 diagnosis confirmed by real-time PCR test or chest CT findings. Most FMF patients with COVID-19 (58) had mild and moderate disease activity. All patients were on colchicine treatment. However, 8 of them (13.6%) were not compliant with colchicine use and 9 of them (15.3%) were colchicine resistant. Twelve FMF patients with COVID-19 were hospitalized. There were 4 patients requiring oxygen support. COVID-19 related complications were observed in 2 patients (1 thromboembolism, 1 acute respiratory distress syndrome). Hospitalized COVID-19 patients with FMF were older than non-hospitalized patients (median ages: 51 and 31 years, respectively; p: 0.002). Other FMF-related characteristics were similar between the groups. FMF-related characteristics were not found to be associated with poor outcomes in COVID-19. Thus, FMF may not be a risk factor for poor COVID-19 outcomes.Publication Metadata only Farelede Radyoterapinin Etkileri(2015-04-27T00:00:00Z) TAŞPINAR, ÖZGÜR; AYDIN, TEOMAN; KILIÇ, GÖKHAN; EREN, FATMA; KIZILTAN, HURİYE; KEPEKÇİ, MÜGE; ERİŞ, HİKMET; KESKİN, YAŞAR; ÖZER, ÖMER FARUK; SELEK, ŞAHBETTİN; SEYİTHANOĞLU, MEHMET HAKAN; AYDIN, TEOMAN; KILIC, GÖKHAN; KESKİN, YAŞAR; ÖZER, ÖMER FARUK; SELEK, ŞAHABETTİNPublication Metadata only Clinical course and prognostic factors of COVID-19 infection in patients with chronic inflammatory-rheumatic disease: A retrospective, case-control study(2022-09-01T00:00:00Z) Nas, Kemal; Guclu, Ertugrul; KESKİN, Yaşar; Dilek, Gamze; Unan, Mehtap Kalcik; Can, Nurselin; Tekeoglu, Ibrahim; Kamanli, Ayhan; KESKİN, YAŞARObjectives: This study aims to investigate the prognosis of novel coronavirus disease-2019 (COVID-19) infection in patients with the chronic inflammatory-rheumatic disease and evaluate the effects of immunosuppressive drugs on the prognosis, clinical characteristics, laboratory findings and hospitalization periods of the rheumatic patients with COVID-19 infection. Patients and methods: Between April 2020 and March 2021, a total of 101 patients (30 males, 71 females; mean age: 48±14.4 years; range, 46 to 48 years) with the rheumatic diseases diagnosed with COVID-19 infection were included. A total of 102 age- and sex-matched patients (35 males, 67 females; mean age: 44±14.4 years; range, 28 to 44 years) who were diagnosed with COVID-19 infection and had no history of rheumatic disease in the same period were included as the control group. Data including demographic characteristics of the patients, presence of any symptoms of COVID-19 disease, laboratory data at the time of diagnosis, and treatments administered were collected. Results: The rate of hospitalization was higher in 38 (37%) patients without rheumatic diseases than in 31 (31%) patients with rheumatic diseases (p=0.324). The rate of lung infiltration on radiographic examination was higher in patients without rheumatic diseases (40% vs. 49%) (p=0.177). COVID-19 infection symptoms such as anosmia 45 (45%), ageusia 51 (50%), shortness of breath 45(45%), nausea 29 (29%), vomiting 16 (16%), diarrhea 25 (25%) and myalgia-arthralgia 81 (80%) were higher in patients with rheumatic diseases. In terms of laboratory values, lymphocyte count (p=0.031) was statistically higher in patients without rheumatic diseases. Hydroxychloroquine (35%), oseltamivir 10 (10%), antibiotics 27 (26%), acetylsalicylic acid 52 (51%), and supplementary oxygen 25 (25%) treatments which used to cure COVID 19 infection were administered more in patients without rheumatic diseases. The number of treatments administered was higher in patients without rheumatic diseases (p<0.001). Conclusion: Patients with the chronic inflammatory-rheumatic disease have more symptoms due to COVID-19 infection, but the disease course is not poor and hospitalization rates are lower.Publication Metadata only Comparing the efficacy of exercise, internal and external shoe modification in pes planus: A clinical and pedobarographic study(2017-01-01T00:00:00Z) TASPINAR, Ozgur; Kabayel, Derya Demirbag; Ozdemir, Ferda; Tuna, Hakan; Keskin, YAŞAR; MERCİMEK, Oznur Berke; Sut, Necdet; Yavuz, Selcuk; Tuna, Filiz; KESKİN, YAŞARPes planus is a condition that can cause pain along the innerfoot due to the absence or abnormal depression of the longitudinal arch. There are few studies available that compare therapy modalities used in these patients. In our study, those treated with conservative therapies-internal and external shoe modifications and pes planus exercises -were compared clinically and pedobarographyically. 60 pes planus patients were included in the study. In the first group; internal modification was performed by placing a medial longitudinal arch support inside the shoe. In the second group, external shoe modification was performed using the Thomas heel. In the third group of patients however, only an exercise program was executed. The patients- foot pain levels, functional asssessment, satisfaction and quality of life were recorded. Pedobarography was used in measuring both static and dynamic plantar pressure. Assessments were carried out at baseline and at the end of the first and third months respectively where intra-and inter-group comparisons were performed. Each group was composed of 20 subjects. While improvement in terms of foot pain, foot function index and quality of life was observed in all the study groups (p < 0.05), the most improvement was observed in the group of patients treated with internal modification (p < 0.016). This was followed by the external modification and the exercise groups respectively. No difference was observed between the internal and external modification groups in terms of patient satisfaction. Cross-sectionally; clinical assessments, pedobarographic analysis were correlated. The changes observed after static and dynamic pedobarographic studies were not significantly different between the study groups. At the end of the study it was observed that internal modification yielded the most significant clinical improvement. In the literature, there are limited publications comparing the conservative treatments with each other. In this study we aimed to compare the conservative treatments for flatfoot.Publication Metadata only Association between nutritional status and Modic classification in degenerative disc disease(2016-04-01) TASPINAR, Ozgur; Seyithanoglu, Hakan; CAMLI, Adil; KIZILTAN, Huriye; HOCAOGLU, Ilknur Turk; Aydin, TEOMAN; Keskin, YAŞAR; Ozder, ACLAN; Eris, ALİ HİKMET; DENIZLI, Ebru; KEPEKCI, Muge; SEYİTHANOĞLU, MEHMET HAKAN; AYDIN, TEOMAN; ERİŞ, ALİ HİKMET; ÖZDER, ACLAN; KESKİN, YAŞAR[Purpose] This study was conducted to examine the association between Modic classification and the eating habits in patients with degenerative disc disease (DDD) and to determine the influence of nutrition on disease severity. [Subjects and Methods] Sixty patients with DDD visiting a low back pain outpatient clinic were enrolled. Through face-to-face interviews, they completed questionnaires regarding their demographics, disease activity, smoking and alcohol use, concomitant diseases, disease duration, and nutritional status. Exclusion criteria were age 65 years, other comorbidities, missing MRI data, and inability to speak Turkish. [Results] Forty patients were finally included in the study. The frequency with which they consumed water, salt, fast food, eggs, milk, yogurt, cheese, whole wheat bread, white bread, butter, and margarine was recorded. A weak negative correlation was observed between the Modic types and fish and egg consumption. [Conclusion] Modic changes, which indicate the severity of DDD, seem to be correlated to patients- dietary habits. However, studies with comparison groups and larger samples are needed to confirm our promising results before any cause-and-effect relationship can be proposed.Publication Metadata only A Gender-based Analysis of Disease Activity and Its Relationship with Anxiety, Depression, Fatigue, and Fibromyalgia in Psoriatic Arthritis(2019-11-08) DURUÖZ, MEHMET TUNCAY; GEZER, HALİSE HANDE; NAS, KEMAL; KILIÇ, ERKAN; sargın, betül; acer kasman, sevtap; ALKAN, HAKAN; ŞAHİN, NİLAY; cengiz, gizem; CÜZDAN COŞKUN, NİHAN; ALBAYRAK GEZER, İLKNUR; KESKİN, ESRA DİLEK; mülkoğlu, cevriye; REŞORLU, HATİCE; ATAMAN, ŞEBNEM; BAL HASTÜRK, AJDA; KÜÇÜKAKKAŞ, OKAN; ALKAN MELİKOĞLU, MELTEM; aydın, yıldıray; AYHAN, FİKRİYE FİGEN; BODUR, HATİCE; ÇALIŞ, MUSTAFA; ÇAPKIN, ERHAN; DEVRİMSEL, GÜL; GÖK, KEVSER; YURDAKUL, OZAN VOLKAN; KAMANLI, AYHAN; KESKİN, YAŞAR; ECESOY, HİLAL; kutluk, öznur; şen, nesrin; ŞENDUR, ÖMER FARUK; TEKEOĞLU, İBRAHİM; TOLU, SENA; TOPRAK, MURAT; TUNCER, TİRAJE; YURDAKUL, OZAN VOLKAN; KESKİN, YAŞARPublication Metadata only Psoriatik Artrit Başlama Yaşına Göre Klinik Özelliklerinin Karşılaştırılması: Çok Merkezli TRASD-Network Projesi(2019-03-24T00:00:00Z) EROL, KEMAL; NAS, KEMAL; KILIÇ, ERKAN; TEKEOĞLU, İBRAHİM; SARGIN, BETÜL; ACER KASMAN, SEVTAP; ALKAN, HAKAN; ŞAHİN, NİLAY; CENGİZ, GİZEM; CÜZDAN, NİHAN; ALBAYRAK GEZER, İLKNUR; KESKİN, ESRA DİLEK; MÜLKOĞLU, CEVRİYE; REŞORLU, HATİCE; BAL HASTÜRK, AJDA; DURUÖZ, MEHMET TUNCAY; KÜÇÜKAKKAŞ, OKAN; SUNAR, İSMİHAN; YURDAKUL, OZAN VOLKAN; ALKAN MELİKOĞLU, MELTEM; AYDIN, YILDIRAY; AYHAN, FİKRİYE FİGEN; BODUR, HATİCE; ÇALIŞ, MUSTAFA; ÇAPKIN, ERHAN; DEVRİMSEL, GÜL; GÖK, KEVSER; HİZMETLİ, SAMİ; KESKİN, YAŞAR; KAMANLI, AYHAN; KOCABAŞ, HİLAL; KUTLUK, ÖZNUR; ŞEN, NESRİN; ŞENDUR, ÖMER FARUK; TOLU, SENA; TOPRAK, MURAT; TUNCER, TİRAJE; YURDAKUL, OZAN VOLKAN; KESKİN, YAŞAR