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OKYALTIRIK, FATMANUR

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Type: Article × Author: Bayram, MEHMET ×

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Now showing 1 - 10 of 13
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    PublicationOpen Access
    [Relationship between symptoms of obstructive sleep apnea syndrome and traffic accidents in the city drivers].
    (2013-01-01) Akkoyunlu, MUHAMMED EMİN; KART, L; ULUDAĞ, M; Bayram, MEHMET; ALISHA, G; ÖZÇELIK, H; Karaköse, FATMANUR; SEZER, M; AKKOYUNLU, MUHAMMED EMİN; BAYRAM, MEHMET; OKYALTIRIK, FATMANUR
    Introduction: There is a high tendency for traffic accidents in patients with obstructive sleep apnea syndrome (OSAS). Thus it's recommended to investigate OSAS symptoms before certification of professional drivers. However, to what degree OSAS symptoms predict traffic accidents is not clear. We aimed to investigate the relationship between OSAS symptoms and traffic accidents. Materials and methods: Five hundred twenty bus drivers working at Istanbul Electricity, Tramway and Tunnel (IETT) general management were randomly selected. Berlin questionnaire was applied which included demographic data, accident ratios, total duration in profession, duration of working in a day and OSAS symptoms. Epworth sleepiness score (ESS) test was applied to assess day time slepiness. Results: All drivers were male. Snoring were present in 324 (65.7%) of participants. Traffic accident history were present in 259 (49.7%) of drivers. Significant relationship was present between traffic accident and only daytime sleepiness among the OSAS symptoms. The mean of accident/year ratio of all participants were 0.092. Mean of ESS was 7.3 ± 3.2 for all participants. There is a positive correlation between ESS and accident/year ratio (r= 0.57, p= 0.012). Conclusion: Only daytime sleepiness among OSAS symptoms is related with traffic accident. The questioning of OSAS symptoms alone is inadequate to estimate traffic accident risk. Thus further consideration more than symptom questioning is needed at phase of authorization of professional drivers to detect OSAS.
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    PublicationOpen Access
    [The frequency and properties of REM related obstructive sleep apnea among the patients with mild related obstructive sleep apnea].
    (2013-01-01) Kutbay, Özçelik; Akkoyunlu, MUHAMMED EMİN; BOSTANLı, P; Bayram, MEHMET; ATAHAN, E; SEZER, M; Karaköse, FATMANUR; KART, L; AKKOYUNLU, MUHAMMED EMİN; BAYRAM, MEHMET; OKYALTIRIK, FATMANUR
    Hafif obstrüktif uyku apneli hastalarda REM ile ilişkili obstrüktif uyku apne sıklığı ve özellikleri Giriş: REM ile ilişkili obstrüktif uyku apne (OUA), “Hafif ve orta OUA olgularında daha fazla görülmesi nedeniyle uykuda solunum bozuklukları spektrumunun erken bir işareti midir?” yoksa “Tamamen ayrı bir antite midir?” sorusuyla araştırmacıların son zamanlarda oldukça dikkatini çekmektedir. Bu çalışmada, hafif OUA tanılı hastalar arasında REM ile ilişkili OUA hastalarının sıklığını ve diğer hafif OUA tanılı hastalardan farkını görmek; ayrıca REM ile ilişkili OUA hastalarında gündüz aşırı uykululuk ile apne ilişkisini değerlendirmek amaçlanmıştır. Materyal ve Metod: 1 Ağustos 2010 ile 29 Şubat 2012 tarihleri arasında Bezmialem Vakıf Üniversitesi Uyku Laboratuvarında polisomnografi tetkiki yapılan toplam 1267 hasta arasından, 134 hafif OUA [Apne hipopne indeksi (AHİ)= 5-15] tanılı hasta retrospektif olarak değerlendirildi. REM AHİ/non-REM AHİ ≥ 2 olan ve non-REM AHİ < 15 olanlar; REM ile ilişkili OUA olarak kabul edildi. Bulgular: Toplam 134 hafif OUA tanılı hastadan 80 (%59)’i REM ile ilişkili OUA olarak değerlendirildi. REM ilişkili OUA ve diğer hafif OUA’lılar yaş, cinsiyet, gündüz aşırı uykululuk, beden kitle indeksi, boyun çevresi ve ek hastalık varlığı açısından karşılaştırıldığında; REM ile ilişkili OUA grubunda yalnızca yaş ortalaması anlamlı olarak düşük bulundu. REM ile ilişkili OUA grubunun %87.3’ünde REM AHİ 15’in üzerinde; %39.3’ünde 30’un üzerindeydi. REM ile ilişkili OUA olgularında; REM AHİ ile gündüz aşırı uykululuk semptomu arasında anlamlı ilişki saptanmadı (p= 0.81). Sonuç: Hafif OUA olguları arasında, REM ile ilişkili OUA grubunun yaş ortalamasının daha düşük olması, REM OUA’nın “uykuda solunum bozuklukları spektrumunun erken bir işareti” olabileceğini düşündürebilir. Bu grup hastaların klinik takibinin bu sorunun cevabı açısından yararlı olacağı kanısındayız.
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    Does CPAP treatment lead to gastroesophageal reflux in moderate and severe OSA case.
    (2014-09-01) OZCELIK, Hatice Kutbay; DANALIOGLU, Ahmet; Bayram, MEHMET; Akkoyunlu, MUHAMMED EMİN; YAKAR, Fatih; KARAKOSE, Fatmanur; SEZER, Murat; BAYRAM, MEHMET; AKKOYUNLU, MUHAMMED EMİN; OKYALTIRIK, FATMANUR
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    COPD: an underdiagnosed disease at hospital environment
    (2014-02-01) Kart, Levent; Akkoyunlu, MUHAMMED EMİN; Bayram, MEHMET; YAKAR, Fatih; OZCELIK, Hatice Kutbay; KARAKOSE, Fatmanur; SEZER, Murat; AKKOYUNLU, MUHAMMED EMİN; BAYRAM, MEHMET; OKYALTIRIK, FATMANUR
    Background and Aim Chronic obstructive pulmonary disease (COPD) is a serious disease with morbidity and mortality due to delayed diagnosis until significant symptoms arise. We aimed to assess the utility of spirometry and COPD Assessment Test (CAT) in detecting undiagnosed COPD patients in a localized area.
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    Geriatric patients with known acute kidney injury and normal renal function at the time of admittance to the intensive care unit/assessment of RRT requirement and mortality: retrospective case-control study
    (2015-04-01) KARAKOSE, Fatmanur; AKKOYUNLU, Muhammet Emin; ERKOC, Reha; KANSU, ABDULLAH; Bayram, MEHMET; SEZER, Murat; OZCELIK, Hatice; Kart, Levent; OKYALTIRIK, FATMANUR; KANSU, ABDULLAH; BAYRAM, MEHMET
    Background The objective of our study was to investigate the renal functions on admittance, chronic disease status, the diagnosis on admittance to the intensive care unit (ICU), need for mechanical ventilation and medication groups and their impact over mortality and renal replacement treatment (RRT) requirement in geriatric patients with and without known acute kidney injury (AKI) at the time of admittance.
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    PERCUTANEOUS ENDOSCOPIC GASTROSTOMY APPLICATION TO GERIATRIC PATIENTS IN INTENSIVE CARE UNIT
    (2013-01-01) Akkoyunlu, MUHAMMED EMİN; Kart, Levent; Akkoyunlu, YASEMİN; DANALIOGLU, Ahmet; KUTBAY OZCELIK, Hatice; KARAKOSE, Fatmanur; Bayram, MEHMET; AKKOYUNLU, MUHAMMED EMİN; AKKOYUNLU, YASEMİN; OKYALTIRIK, FATMANUR; BAYRAM, MEHMET
    Introduction: Nutritional support is very important in geriatric patients with insufficient or no oral intake in intensive care units (ICU). The need for active enteral nutrition by means of nutrition tubes in patients with impaired swallowing function, the methods of application and the benefits obtained are still controversial. In this study we aimed to evaluate the problems related with application of percutaneous endoscopic gastrostomy (PEG) to geriatric patients who need intensive care.
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    The role of bariatric surgery in obstructive sleep apnea syndrome
    (2014-10-01) Karaköse, FATMANUR; Bozkurt, SÜLEYMAN; Akkoyunlu, MUHAMMED EMİN; COŞKUN, HALİL; YAKAR, Fatih; Bayram, MEHMET; SEZER, Murat; OZCELIK, Hatice Kutbay; KART, Levent; OKYALTIRIK, FATMANUR; BOZKURT, SÜLEYMAN; AKKOYUNLU, MUHAMMED EMİN; COŞKUN, HALIL; BAYRAM, MEHMET
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    PublicationOpen Access
    Value of Mean Platelet Volume for Disease Activity in Patients with Pulmonary Sarcoidosis
    (2017-01-01) OZCELIK, Hatice Kutbay; Bayram, MEHMET; KILIC, Elif; Akkoyunlu, MUHAMMED EMİN; SEZER, Murat; KARAKOSE, Fatmanur; YAKAR, Fatih; BAYRAM, MEHMET; AKKOYUNLU, MUHAMMED EMİN; OKYALTIRIK, FATMANUR
    Objective: We aimed to investigate the importance of mean platelet volume (MPV) as a marker for the activation and severity of disease in patients with pulmonary sarcoidosis.
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    Relationship of CTLA4 and CD28 polymorphisms with lung involvement, HRCT findings and pulmonary function tests in Turkish patients with ankylosing spondylitis
    (2017-09-01) Okyaltirik, FATMANUR; Rezvani, AYLİN; Turan, Saime; Uysal, Omer; YAKAR, Fatih; SÖZGEN, Hatice; Ozkan, Nazli Ezgi; Akkoyunlu, Muhammet Emin; Bayram, MEHMET; Ozcelik, Hatice Kutbay; Sezer, Murat; GÜLER, Mustafa; Yaylim, Ilhan; Kart, Levent; OKYALTIRIK, FATMANUR; REZVANİ, AYLİN; UYSAL, ÖMER; BAYRAM, MEHMET
    Background and AimsAnkylosing spondylitis (AS) is a multisystem disorder with ocular, pulmonary, and cardiovascular involvement. The incidence of pulmonary involvement varies from 1 to 52%. Abnormal T-cell function-derived immune responses are involved in AS pathogenesis. Numerous genes such as CTLA4 and CD28 control T-cell functions. In this study, we aimed to address the relationship between CTLA4 and CD28 polymorphisms and lung involvement in Turkish patients with AS.
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    PublicationOpen Access
    Does hormonal control obviate positive airway pressure therapy in acromegaly with sleep-disordered breathing?
    (2013-11-01) Akkoyunlu, MUHAMMED EMİN; Ilhan, MAHMUT MUZAFFER; Bayram, MEHMET; Tasan, ERTUĞRUL; YAKAR, Fatih; OZCELIK, Hatice Kutbay; KARAKOSE, Fatmanur; Kart, Levent; AKKOYUNLU, MUHAMMED EMİN; İLHAN, MAHMUT MUZAFFER; BAYRAM, MEHMET; TAŞAN, ERTUĞRUL; OKYALTIRIK, FATMANUR
    Acromegaly is a disease in which uncontrolled release of growth hormone occurs after closure of epiphyseal plates, causing changes in the body that can lead to sleep disordered breathing (SDB). No definite guidelines regarding the treatment of SDB in acromegaly are available. In this study, we aimed to investigate the prevalence of SDB in acromegaly and whether hormonal control alters the necessity of positive airway pressure (PAP) therapy in acromegaly patients with SDB. Methods: Forty-two acromegaly patients were included in the study and divided into two groups according to disease status, i.e., active or well controlled. All patients underwent polysomnography. Fourteen patients with active acromegaly were diagnosed with SDB and were evaluated for PAP therapy with polysomnography both before and 6 months after disease control was achieved. Results: Sleep-disorder breathing was diagnosed in 22 of 42 patients, 7 of 20 patients with controlled-disease and 15 of 20 patients with active diseases. There were significant reductions in respiratory disturbance index (RDI), apnea index, desaturation index, central apnea number, and rapid eye movement-phase RDI at the control polysomnography. Initially, PAP therapy was indicated in 12 of 14 patients and PAP therapy indication held in 11 patients after acromegaly control was achieved. Conclusion: Our study revealed that over half of patients with acromegaly had SDB. Furthermore, SDB severity decreases with acromegaly treatment; however, this decrease does not