Person: SÖNMEZ, ERTAN
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Publication Metadata only Investigation of the effectiveness of the Quick Sequential Organ Failure Assessment-Troponin scores in non- ST-elevation myocardial infarction(2023-02-01) Cander B.; Taşlıdere B.; Sönmez E.; CANDER, BAŞAR; TAŞLIDERE, BAHADIR; SÖNMEZ, ERTANOBJECTIVE: A reliable predictor is needed for non-ST-elevation myocardial infarction patients with high mortality risk. The aim of this study was to assess the effectiveness of the Global Registry of Acute Coronary Events and Quick Sequential Organ Failure Assessment-Troponin (qSOFA-T) scores on in-hospital mortality rate in non-ST-elevation myocardial infarction patients. METHODS: This is an observational and retrospective study. Patients admitted to the emergency department with acute coronary syndrome were evaluated consecutively. A total of 914 patients with non-ST-elevation myocardial infarction who met inclusion criteria were included in the study. The Global Registry of Acute Coronary Events and qSOFA scores were calculated and investigated its contribution to prognostic accuracy by adding cardiac troponin I (cTnI) concentration to the qSOFA score. The threshold value of the investigated prognostic markers was calculated by receiver operating characteristic curve analysis. RESULTS: We found the in-hospital mortality rate to be 3.4%. The area under the receiver operating characteristic curve for Global Registry of Acute Coronary Events and qSOFA-T is 0.840 and 0.826, respectively. CONCLUSION: The qSOFA-T score, which can be calculated easily, quickly, and inexpensively and obtained by adding the cTnI level, had excellent discriminatory power for predicting in-hospital mortality. Difficulty in calculating the Global Registry of Acute Coronary Events score, which requires a computer, can be considered a limitation of this method. Thus, patients with a high qSOFA-T score are at an increased risk of short-term mortality. KEYWORDS: Acute coronary syndrome. Troponin I. Mortality. Non-ST elevated myocardial infarction.Publication Metadata only Evaluation of patients admitted to the emergency department after Coronavac (Sinovac) vaccination?(2023-03-01) Taşlıdere B.; Sönmez E.; Özdemir S.; TAŞLIDERE, BAHADIR; SÖNMEZ, ERTANTo evaluate the symptoms and laboratory parameters of patients admitted to the emergency department after CoronaVac (Sinovac) vaccination. Complaints, demographic characteristics, laboratory tests, interventions, and outcomes of patients admitted to the emergency department within seven days of receiving the CoronaVac (Sinovac) were all evaluated. Pain at the injection site, swelling, redness, and pain in the injected arm were expected side effects of the vaccination. In this study, a total of six people had syncope following the vaccination, one of whom developed an allergic reaction. The most common adverse events in non-geriatrics were fatigue, headache, fever, and abdominal pain, while in geriatric patients’ fatigue, headache, chest pain, and dyspnea were most common, with fever falling in the last place. Rare symptoms following vaccination included syncope and urticaria. It is necessary to be prepared for the side effects that may occur during mass vaccination against COVID-19. In this study, the body’s response to the vaccine in geriatric patients was atypical in vital signs and laboratory values.Publication Metadata only Investigation of Total Antioxidant Status and Total Oxidant Status with Seizure Types in Patients with Epilepsy(2022-01-01) TAŞLIDERE B.; USLU F.; SÖNMEZ E.; SELEK Ş.; TAŞLIDERE, BAHADIR; USLU, FERDA; SÖNMEZ, ERTAN; SELEK, ŞAHABETTİNBACKGROUND/AIMS: As epilepsy is a complex disease group, it is difficult to diagnose and classify. Oxidative stress plays a vital role in the pathogenesis of epilepsy. This study investigated the total oxidant/antioxidant status levels in patients with focal onset and generalized onset seizures. The results we obtained may help find the etiological cause in patients with seizure complaints and may guide their treatment. In addition, knowing the seizure type of the patient can give an idea about the prognosis of their disease.MATERIALS AND METHODS: The total number of patients included in this prospective study was 58. There were also 57 people in a control group. The patients were classified according to their type of seizure: focal or generalized onset. The serum oxidative stress index (OSI) and total oxidant/antioxidant status values of all patients and control group members were measured. The patients (focal/generalized groups) and control group members were compared.RESULTS: This prospective study was completed with 58 eligible patients who met the inclusion criteria. There were 57 people in the control group. Total oxidant status (TOS) and OSI levels were higher in the seizure groups compared to the control group (p<0.05). The difference between the serum TOS and OSI levels of patients with generalized or focal onset seizures was statistically significant.CONCLUSION: Classifying patients according to their seizure types by looking at their oxidative stress levels can guide treatment (in terms of investigating antioxidant activity) and give an idea about prognosis. This study showed the importance of TOS and OSI levels in patients presenting with seizures. This was particularly evident in generalized onset seizures. An evaluation of serum TOS and OSI levels in patients presenting with seizures may help us in clinical diagnosis, treatment, and classification.Keywords: Epilepsy, total oxidant status, seizure types, total antioxidant status