Person: BARAN, GÖZDE
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Publication Metadata only Relationship between localizations and etiologies in patients with brainstem infarctions(2014-10-01) BARAN, GÖZDE; OZTURK, T.; KOLUKISA, MEHMET; ARALASMAK, AYŞE; BOHLOULI, E.; Asil, TALİP; BARAN, GÖZDE; KOLUKISA, MEHMET; ARALAŞMAK, AYŞE; ASİL, TALIPPublication Open Access Association between etiology and lesion site in ischemic brainstem infarcts: a retrospective observational study.(2018-03-13) BARAN, GÖZDE; GULTEKIN, TO; BARAN, O; DENIZ, C; KATAR, SELAHATTİN; Yildiz, GÜLSEN; ASIL, TALİP; BARAN, GÖZDE; DENİZ, ÇİĞDEM; KATAR, SELAHATTİN; BABACAN YILDIZ, GÜLSEN; ASİL, TALIPBackground and purpose: To assess the anatomical distribution of the ischemic strokes of the brainstem, the effect of anatomical distribution on clinical features and prognosis, and the association between etiology and anatomical involvement. Methods: A retrospective search of the patient database of our institution was performed for a total of 227 patients who were admitted to the Department of Neurology, Medical Faculty of Bezmialem Vakif University between January 2012 and September 2014. Patients with adequate diagnostic data and 3-month follow-up visit were included in the study. Results: Twenty-one (9%), 136 (60%), and 65 (29%) patients had an infarction only at the mesencephalon, pons, and medulla, respectively. However, a single patient (0.5%) had an infarction both at the mesencephalon and pons, 3 (1.5%) at the pons and medulla, and 1 (0.5%) at the mesencephalon, pons, and medulla. While anterior involvement was more common in the mesencephalon and pons, posterior and lateral involvement occurred more frequently in the medulla. Large arterial atherothrombosis was the predominant cause of the strokes in all anatomical sites, particularly in infarcts involving the pons. Cardioembolic events were more common in patients with mesencephalic infarcts. Also, ischemia due to dissection was more common in infarctions involving the medulla, especially the lateral medulla. In subjects with simultaneous infarcts at other sites in addition to the brainstem, there was a significantly higher co-occurrence of medullary infarcts with cerebellar infarcts, mesencephalic infarcts with posterior cerebral artery infarcts, and pons infarcts with anterior circulation and multiple infarcts. Conclusion: Determination of risk factors and infarct localization as well as prediction of etiological parameters may assist in improving survival rates and therapeutic approaches.Publication Metadata only Expression of miRNA-21, miRNA-107, miRNA-137 and miRNA-29b in meningioma(2017-05-01T00:00:00Z) Katar, Salim; Baran, Oguz; Evran, Sevket; Cevik, Serdar; Akkaya, Enes; Baran, Gozde; Antar, Veysel; Hanimoglu, Hakan; Kaynar, Mehmet Yasar; BARAN, GÖZDEObjective: Meningiomas are among the most common intracranial tumors, accounting for 30% of all tumors of the central nervous system. Recent studies analyzing microRNA (miRNA) profiles and functions in cancer have provided valuable information about the molecular pathogenesis of several tumor types, including glioblastoma multiforme (GBM), hepatocellular carcinoma, and breast, lung, colon, and prostate cancer. miRNAs are a family of small, endogenous, noncoding RNAs of 18-25 nucleotides. In this study, we carried out a genome-wide array screen comparing miRNA-21, miRNA-107, miRNA-137 and miRNA-29b expression in meningiomas.Publication Metadata only Bilateral jugular vein and sigmoid sinus thrombosis related to an inherited coagulopathy: an unusual presentation.(2014-01-01) ALTıNTAŞ, O; Gürsoy, AZİZE ESRA; BARAN, GÖZDE; MEHDI, E; ASIL, TALİP; GÜRSOY, AZIZE ESRA; BARAN, GÖZDE; ASİL, TALIPPublication Metadata only Progressive deficit in isolated pontine infarction: the association with etiological subtype, lesion topography and outcome(2017-09-01T00:00:00Z) GÖKÇAL, ELİF; Niftaliyev, Elvin; Baran, Gozde; DENİZ, ÇİĞDEM; ASİL, Talip; GÖKÇAL, ELİF; BARAN, GÖZDE; DENİZ, ÇİĞDEM; ASİL, TALIPIt is important to predict progressive deficit (PD) in isolated pontine infarction, a relatively common problem of clinical stroke practice. Traditionally, lacunar infarctions are known with their progressive course. However, few studies have analyzed the branch atheromatous disease subtype as a subtype of lacunar infarction, separately. There are also conflicting results regarding the relationship with the topography of lesion and PD. In this study, we classified etiological subtypes and lesion topography in isolated pontine infarction and aimed to investigate the association of etiological subtypes, lesion topography and clinical outcome with PD. We analyzed demographics, laboratory parameters, and risk factors of 120 patients having isolated pontine infarction and admitted within 24 h retrospectively. PD was defined as an increase in the National Institutes of Health Stroke scale >= 2 units in 5 days after onset. Patients were classified as following: large artery disease (LAA), basilar artery branch disease (BABD) and small vessel disease (SVD). Upper, middle and lower pontine infarcts were identified longitudinally. Functional outcome at 3 months was determined according to modified Rankin scores. Of 120 patients, 41.7% of the patients were classified as BABD, 30.8% as SVD and 27.5% as LAA. 23 patients (19.2%) exhibited PD. PD was significantly more frequent in patient with BABD (p 0.006). PD was numerically higher in patients with lower pontine infarction. PD was associated with BABD and poor functional outcome. It is important to discriminate the BABD neuroradiologically from other stroke subtypes to predict PD which is associated with poor functional outcome in patients with isolated pontine infarctions.Publication Metadata only The Relationship of Hematoma Growth to Red Blood Cell Distribution Width in Patients with Hypertensive Intracerebral Hemorrhage(2017-05-01) ALTINTAS, Ozge; DURUYEN, Humeyra; BARAN, GÖZDE; BARAN, Oguz; KATAR, Salim; ANTAR, Veysel; Asil, TALİP; BARAN, GÖZDE; ASİL, TALIPAIM: Hypertension is a primary risk factor for intracerebral hemorrhage (ICH) and is thought to be responsible for about 55% of all ICH cases. Thus, the primary goal of the study was to examine whether the status of vascular rheological factors upon admission to the hospital was associated with hypertensive ICH growth and early outcomes.