Person: KAYA, MEHMET ONUR
7 results
Search Results
Now showing 1 - 7 of 7
Publication Metadata only Evaluation of CSF flow metrics in patients with communicating hydrocephalus and idiopathic intracranial hypertension(2019-05-01) Yilmaz, TEMEL FATİH; Aralasmak, AYŞE; Toprak, HÜSEYİN; MEHDI, Elnur; KOCAMAN, Gulsen; Kurtcan, SERPİL; Kaya, MEHMET ONUR; Alkan, ALPAY; YILMAZ, TEMEL FATİH; ARALAŞMAK, AYŞE; TOPRAK, HÜSEYİN; KURTCAN, SERPİL; KAYA, MEHMET ONUR; ALKAN, ALPAYPurpose To search for CSF dynamics of idiopathic intracranial hypertension (IIH) and communicating hydrocephalus and any correlation between MRI findings, CSF metrics and CSF opening pressure in IIH.Publication Open Access Investigating academic veterinarians- knowledge of biostatistics: a web-based survey(2015-01-01) Ocakoglu, Gokhan; Ercan, Ilker; Kaya, MEHMET ONUR; Uzabaci, Ender; Can, Fatma Ezgi; KAYA, MEHMET ONURThe primary aim of our study, web-based survey, is to gain an understanding of veterinarians- statistical knowledge and how it varies by focus area. The secondary aim is to address the following question: when should biostatistics be taught in veterinary education? A total of 155 veterinarians from 41 countries participated in this study. The results indicate that while veterinarians place an emphasis on biostatistics education, the majority state that biostatistics education should be taken both at the undergraduate and postgraduate level and the participants also believe that taking a biostatistics course is useful for their occupation. In biostatistics education, the topic of sampling, which plays a significant role at the planning stage of any study, should be considered particularly important. A biostatistics education should also emphasize the necessity of consulting to a biostatistician when planning a study.Publication Open Access Vitamin D status in the first-trimester: effects of Vitamin D deficiency on pregnancy outcomes(2016-01-01) Ates, SEDA; Sevket, OSMAN; ÖZCAN, PINAR; ÖZKAL, Fulya; Kaya, MEHMET ONUR; Dane, Banu; ATEŞ, SEDA; ŞEVKET, OSMAN; ÖZCAN, PINAR; KAYA, MEHMET ONUR; KILIÇOĞLU DANE, PAKİZER BANUObjective: To assess serum levels of 25-hydroxyvitamin D [25(OH)D] in the first trimester and to determine the factors affecting deficiency levels and its association with pregnancy outcomes. Methods: Serum 25(OH)D concentrations were measured at 11-14 weeks' gestation in 229 singleton pregnancies using liquid chromatography-tandem mass spectrometry. Results: The median serum 25(OH)D concentration was 10.8 ng/mL and 45.9% of women had severe vitamin D deficiency with concentrations of <10 ng/mL. Logistic regression analysis revealed that covered dressing style, lack of multivitamin intake, season of blood sampling (November-April) were factors associated with 25(OH)D deficiency. There was a negative correlation between 25(OH)D levels and gestational age at sampling. Low 25(OH)D levels were not associated with adverse pregnancy outcomes. Higher rate of cesarean section (CS) was noted in women with 25(OH)D ≥10 ng/mL compared to those with 25(OH)D < 10mg/ml (p= 0.01). Conclusion: A high prevalence of vitamin D deficiency was observed in early pregnancy which was related to dress code, use of multi-vitamins and season at sampling. Low 25(OH)D levels were not related with adverse pregnancy outcomes. Women with severe vitamin D deficiency were more likely to deliver vaginally.Publication Open Access Evaluation of mean platelet volume in localized scleroderma(2017-09-01) Bahali, ANIL GÜLSEL; Su, Ozlem; Emiroglu, NAZAN; Cengiz, FATMA PELİN; Kaya, MEHMET ONUR; Onsun, NAHİDE; BAHALI, ANIL GÜLSEL; SU KÜÇÜK, ÖZLEM; EMİROĞLU, NAZAN; CENGİZ, FATMA PELIN; KAYA, MEHMET ONUR; ONSUN, NAHIDEAbstract: Background: Localized scleroderma is a chronic inflammatory skin disease characterized by sclerosis of the dermis and subcutaneous tissue. Platelets play an important role in inflammation. Following activation, platelets rapidly release numerous mediators and cytokines, which contribute to inflammation. Objectives: To evaluate whether there was any relation between localized scleroderma and platelet parameters. Methods: Forty-one patients with localized scleroderma were enrolled in the study. The control group consisted of 30 healthy subjects. Results: The mean platelet volume level in the patient group was 9.9 ± 1.3 fl and in the control group was 7.6 ± 1.1 fl. This difference was statistically significant (p< 0.001). The plateletcrit values are minimally higher in the patient group as compared to the control group. It was statistically significant (p<0.001). There was no significant difference in the platelet counts between the two groups (p= 0.560) In the patient group, there was no significant relation between the mean platelet volume levels and clinical signs of disease (p=0.09). However, plateletcrit values are higher in generalized than localized forms of disease (p=0.01). Study Limitations: The limited number of patients and the retrospective nature of the study were our limitations. Conclusions: This study suggests that platelets might play a role in the pathogenesis of scleroderma. Platelet parameters may be used as markers for evaluating disease severity and inflammatory processes. Thus, there is a need for more detailed and prospective studies. Keywords: Blood platelets; Scleroderma, localized; Transforming growth factor betaPublication Open Access Evaluation of Mean Platelet Volume in Patients with Pigmented Purpuric Dermatosis(2017-01-01) Su, Ozlem; Bahali, ANIL GÜLSEL; OZKAYA, Dilek Biyik; Cengiz, FATMA PELİN; Emiroglu, NAZAN; Kaya, MEHMET ONUR; Onsun, NAHİDE; BAHALI, ANIL GÜLSEL; BIYIK ÖZKAYA, DİLEK; CENGİZ, FATMA PELIN; EMİROĞLU, NAZAN; SU KÜÇÜK, ÖZLEM; KAYA, MEHMET ONUR; ONSUN, NAHIDEObjective: Pigmented purpuric dermatosis (PPD) is a chronic skin disease characterized by petechial and pigmentary macules. The etiology of the disease remains unknown. Mean platelet volume (MPV) is a marker of platelet (PLT) function and activation. PLTs play important roles in inflammation and innate and adaptive immunity in addition to their roles in hemostasis and thrombosis. In this study, we investigated the possible association between MPV and PPD.Publication Open Access EXAMINATION OF PUBLISHED ARTICLES WITH RESPECT TO STATISTICAL ERRORS IN VETERINARY SCIENCES(2017-03-01T00:00:00Z) ERCAN, İLKER; KAYA, MEHMET ONUR; UZABACI, ENDER; Mankir, Seray; CAN, FATMA EZGİ; Bashir Albishir, Musa; KAYA, MEHMET ONURThe aim of this present work was to examine statistical errors in published veterinary science articles. A total of 204 published articles (SCI or SCI-Exp) were used in this study. The articles were chosen from among those indexed in PubMed database between the years 2010 and 2014, inclusive. A total of 199 articles had at least one statistical error. The most frequently encountered statistical error among the articles published in journals indexed in SCI and in SCI-E was -errors in summarizing data-. No statistical error was found in 2.45% (n=5) of 204 (SCI: 0.98% (1/102), SCI-E: 3.92% (4/102)) articles. To reduce and prevent statistical errors in publications, the researchers must have a basic knowledge of statistics and during the study process they must consult field experts. While reviewing, the reviewers have to redirect the publications to statistical editors when needed and most importantly during the process of editing, the editors have to direct the publications to a statistics reviewer.Publication Metadata only Association of serum YKL-40 level with tumor burden and metastatic stage of prostate cancer.(2012-07-01T00:00:00Z) ÖZDEMIR, E; ÇIÇEK, T; Kaya, MEHMET ONUR; KAYA, MEHMET ONUR