Person: KUNDUZ, ENVER
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Publication Metadata only Videoendoscopic pilonidal sinus surgery: early results with a new technique(2017-12-01) Kunduz, ENVER; Idiz, Ufuk Oguz; Aysan, Erhan; Güzel, MEHMET; Yapalak, YUNUS; Başköy, LÜTFULLAH; KUNDUZ, ENVER; GÜZEL, MEHMET; YAPALAK, YUNUS; BAŞKÖY, LÜTFULLAHWe adapted a laparoscopic surgical technique to sacrococcygeal pilonidal sinus disease (SPSD) treatment.Publication Open Access Comparison of Laparoscopic and Conventional Cystotomy/Partial Cystectomy in Treatment of Liver Hydatidosis(2019-01-01) Bektasoglu, HÜSEYİN KAZIM; HASBAHCECI, Mustafa; Taşçı, Yunus; Aydogdu, Ibrahim; MALYA, FATMA ÜMİT; Kunduz, ENVER; Dolay, KEMAL; BEKTAŞOĞLU, HÜSEYİN KAZIM; AYDOĞDU, İBRAHİM; MALYA, FATMA ÜMİT; KUNDUZ, ENVER; DOLAY, KEMALIntroduction. Hydatidosis is a zoonotic infection and treatment is mandatory to avoid complications. Surgery remains the frst choice in the treatment especially for CE2-CE3b cysts. Open or laparoscopic approaches are available. However, comparative studies are limited. Materials and Methods. Data of patients who underwent cystotomy/partial cystectomy for liver hydatidosis between January 2012 and September 2016 (n=77) were evaluated retrospectively. Recurrent cases and the patients with previous hepatobiliary surgery were excluded. 23 patients were operated upon laparoscopically and named as Group 1. 48 patients operated conventionally named as Group 2. Demographics, cyst characteristics, operative time, length of hospital stay, recurrences, and surgery related complications were evaluated. Results. Groups were similar in terms of demographics, cyst characteristics, and operative time. Te length of hospital stay was 3.4 days in Group 1 and 4.7 days in Group 2 (p=0,007). Te mean follow-up period was 17.8 months and 21.7 months, respectively (p=0.170). Overall complication rates were similar in two groups (p=0.764). Tree conversion cases occurred (13%). One mortality was seen in Group 2. Four recurrences occurred in each group (17% versus 8.3%, respectively) (p=0.258). Conclusions. Laparoscopy is a safe and feasible approach for surgical treatment of liver hydatidosis. Recurrence may be prevented by selection of appropriate cases in which exposure of cysts does not pose an intraoperative difcultyPublication Open Access Co-existence of acute appendicitis and inflammatory myofibroblastic tumor of the small intestine: A case report(2015-09-01) Unver, NURCAN; Coban, GANİME; ONARAN, Oyku Izel; ARSLAN, ADNAN; Malya, FATMA ÜMİT; HASBAHCECI, Mustafa; ÜNVER, NURCAN; ÇOBAN, GANİME; KUNDUZ, ENVER; ARSLAN, ADNAN; MALYA, FATMA ÜMİTIntroduction: Inflammatory myofibroblastic tumor as a rare neoplastic lesion is seen most commonly in the pulmonary system. Beside the presence of limited number of inflammatory myofibroblastic tumors of the gastrointestinal tract in the literature, co-existence with acute appendicitis has not been reported before. Presentation of case: A 27-year-old woman admitted to emergency department with acute abdominal pain at the right lower quadrant. The initial diagnosis was as acute appendicitis. Intraoperatively, a mass with a diameter of almost 5 cm originated from the distal ileal segments neighboring the appendix was seen. The patient was managed by segmental resection of the small intestine including the mass with appendectomy. Histologically, there were bundles of spindle cells accompanied by lymphoplasmocytic infiltration. The immunohistochemical studies showed that tumor cells were positive for smooth muscle actin, vimentin, perinuclear activity for anaplastic lymphoma kinase and CD 68. The final pathologic diagnosis was inflammatory myofibroblastic tumor. Discussion: Concomitant resection of tumoral lesions detected in the neighbor intestinal segments during appendectomy should be considered to diagnose and treat. For the diagnosis of inflammatory myofibroblastic tumor, immunohistochemistry pattern including positivity for actin, vimentin, CD 68 and anaplastic lymphoma kinase plays a crucial role. Therefore, detailed immunohistochemistry analysis should be performed in suspicious cases. Conclusion: Coexistence of inflammatory myofibroblastic tumor located in the gastrointestinal system with acute appendicitis is a rare event. Complete surgical excision should be regarded as the mainstay of the treatment. Long-term follow up with serial imaging techniques is recommended.Publication Open Access Scalp recurrence of cholangiocarcinoma after curative hepatectomy: A report of two cases(2017-12-01) Kunduz, ENVER; Serin, Kursat Rahmi; Şeker, MESUT; KUNDUZ, ENVER; ŞEKER, MESUTCholangiocarcinomas are the second most common primary liver malignancies. The lymphatics are the common route of metastatic spread for cholangiocarcinomas. The most frequent sites of metastasis are the liver, abdominal lymph nodes, peritoneum and lungs. Cutaneous metastasis of cholangiocarcinoma is rare, and most commonly occurs following percutaneous biliary drainage. Brain or skull metastases from this tumor are uncommon. However, these rare metastatic lesions may occasionally be the first disease manifestation, although scalp recurrence following curative treatment is uncommon. We herein present the cases of two patients with cholangiocarcinoma, who were evaluated as resectable based on the criteria for cholangiocarcinoma resectability, and developed scalp recurrence following curative hepatectomy. Therefore, although scalp recurrence is a rare occurrence following curative treatment for cholangiocarcinoma, metastases should be included in the differential diagnosis.Publication Metadata only Laparoscopic Surgery for Rectal Cancer: Outcomes in 513 Patients(2013-04-01T00:00:00Z) Asoglu, Oktar; Balik, Emre; Kunduz, ENVER; Yamaner, Sumer; Akyuz, Ali; Gulluoglu, Mine; Kapran, Yersu; Bugra, Dursun; KUNDUZ, ENVERBackground Few reports have demonstrated the feasibility and efficacy of laparoscopic resection in patients with rectal cancer (RC). The objective of the present study was to assess the effectiveness of laparoscopic resection for RC, with an emphasis on perioperative variables and long-term oncological outcomes.Publication Open Access Laparoscopic surgery in distal pancreatic tumors(2017-12-01) Malya, FATMA ÜMİT; Bektaşoğlu, HÜSEYİN KAZIM; HASBAHCECI, Mustafa; Taşçı, Yunus; Kunduz, ENVER; Karatepe, Oguzhan; Dolay, KEMAL; MALYA, FATMA ÜMİT; BEKTAŞOĞLU, HÜSEYİN KAZIM; KUNDUZ, ENVER; DOLAY, KEMALObjective: Laparoscopic distal pancreatectomy is increasingly being used in the surgical treatment of corpus and distal pancreatic tumors. In this study, patients who underwent laparoscopic or open distal pancreatectomy for benign or malignant causes were evaluated in terms of tumor characteristics and perioperative outcomes. Material and Methods: We retrospectively reviewed data from a total of 27 distal pancreatectomy cases performed for benign or malignant causes in the General Surgery Department between January 2013 and December 2015. Groups were compared according to the demographic characteristics of patients, operation type (laparoscopic or open, with splenectomy or spleen preservation), operation time, surgical site infection (superficial, deep wound infection, or intra-abdominal abscess), pancreatic fistula development, and histopathological examination results. Results: Both groups were similar in terms of age, sex, and body mass index (p=0.42). Tumor diameter was similar (p=0.18). The total number of resected lymph nodes was similar in both groups (p=0.6). Pancreatic fistula developed in one patient in each group. Mean hospital stay duration and the amount of intraoperative bleeding were similar in both groups. The laparoscopy group had a markedly lower overall morbidity rate (p=0.08). There was no mortality observed in the study subjects. Conclusion: Laparoscopic distal pancreatectomy can be safely performed as a minimally invasive procedure in experienced centers and in selected cases without increasing perioperative complication rates, particularly in benign cases. Although oncological outcomes are acceptable for malignant cases, future prospective controlled studies are necessary for more reliable evaluation. Keywords: Laparoscopy, pancreas, oncologyPublication Open Access Transvaginal Small Bowel Evisceration following Abdominoperineal Resection(2018-01-01) Kunduz, ENVER; Bektasoglu, HÜSEYİN KAZIM; Yigman, SAMET; Akbulut, HÜSEYİN; KUNDUZ, ENVER; BEKTAŞOĞLU, HÜSEYİN KAZIM; YIĞMAN, SAMET; AKBULUT, HÜSEYİNAbdominoperineal resection (APR) is one of the surgical techniques performed for the distal rectal cancer. The perineal herniation is one of the complications of APR surgery. In this report, we aim to demonstrate a rare case of small bowel evisceration and strangulation secondary to the transvaginal herniation evolved in the late stage after perineal hernia repair following laparoscopic APR.Publication Open Access A rare cause of obstructive defecation in a 29-year-old woman: Ileo-colo-colonic intussusception treated by subtotal colectomy with posterior rectopexy(2018-12-01) Kunduz, ENVER; Malya, FATMA ÜMİT; Mehdi, Elnur; HASBAHCECI, Mustafa; KUNDUZ, ENVER; MALYA, FATMA ÜMİTAdult intussusception is a rare clinical condition. In majority of adult cases, there is an underlying cause such as polyps or colon cancers. In the present study, a 29-year-old woman with intermittent and colicky abdominal pain, constipation, and painful defecation, accompanied with distention and sense of rectal fullness, was evaluated with computed tomography. Ileo-colo-colic intussusception was determined. Subtotal colectomy with posterior rectopexy was performed. After the surgery, she was doing well at 13-month follow-up.Publication Metadata only The effect of neoadjuvant therapy on the size, number, and distribution of mesorectal lymph nodes(2016-02-01) Yegen, Gulcin; Keskin, Metin; Buyuk, Melek; Kunduz, ENVER; Balik, Emre; Saglam, Esra Kaytan; Kapran, Yersu; Asoglu, Oktar; Gulluoglu, Mine; KUNDUZ, ENVERThe current therapeutic approach to patients with locally advanced rectal cancer is neoadjuvant radiotherapy or chemoradiotherapy followed by total mesorectal excision. We aimed to investigate the number, size, and distribution of metastatic and nonmetastatic lymph nodes within the mesorectum; whether neoadjuvant therapy has any impact on the number and size of the lymph nodes; and the impact of metastatic lymph node localization on overall and disease-free survival. Specimens from 50 consecutive patients with stage rectal cancer receiving either neoadjuvant radiotherapy or chemoradiotherapy were investigated. Lymph node dissection was carried out by careful visual inspection and palpation. The localization of the each lymph node within the mesorectum and the relation with the tumor site were noted. The size and the number of lymph nodes retrieved decreased significantly with neoadjuvant therapy. Majority of the metastatic and nonmetastatic lymph nodes were located at or proximally to the tumor level and posterior side of the mesorectum. No relation was observed between the overall and disease-free survival, and the localization of the metastatic lymph nodes. Presence of lymph node metastases proximal to the tumor level has no impact on survival compared with the presence of lymph node metastasis only in the peritumoral region of the mesorectum. Although neoadjuvant therapy decreases the size and the number of lymph nodes, reaching an ideal number of lymph nodes for accurate staging is still possible with careful naked eye examination and dissection of perirectal fat. As the majority of metastatic and nonmetastatic lymph nodes are located in peritumoral and proximal compartment, and posterior side of the mesorectum, these regions should be the major interest of dissection. (C) 2015 Elsevier Inc. All rights reserved.Publication Open Access Use of serum and peritoneal CEA and CA19-9 in prediction of peritoneal dissemination and survival of gastric adenocarcinoma patients: are they prognostic factors?(2018-04-01) HASBAHCECI, MUSTAFA; Malya, FATMA ÜMİT; Kunduz, ENVER; Guzel, MEHMET; Unver, NURCAN; Akcakaya, ADEM; MALYA, FATMA ÜMİT; KUNDUZ, ENVER; GÜZEL, MEHMET; ÜNVER, NURCAN; AKÇAKAYA, ADEMINTRODUCTION To evaluate the impact of serum and peritoneal levels of tumour markers on peritoneal carcinomatosis and survival in gastric adenocarcinoma. MATERIALS AND METHODS Patients with gastric adenocarcinoma were evaluated with regard to serum and peritoneal carcinoembryonic antigen (CEA) and CA19-9. Numeric values and groupings based on serum and peritoneal cutoff values were used. Development of peritoneal carcinomatosis, including positive washing cytology, was regarded as main outcome. Gastric cancer outcomes as disease free and overall survival were analysed. RESULTS There were 67 patients with a mean age of 60 ± 11 years. Positive peritoneal washing cytology was significantly associated with serum CA19-9 and high serum CA 19–9 group (P = 0.033 and P = 0.011, respectively). High peritoneal CEA was shown to be significantly associated with peritoneal carcinomatosis (P = 0.032). After a median follow up of 17 months, 48 patients (71.7%) were alive. Patients with peritoneal carcinomatosis showed significant poorer prognosis as shown by overall survival rate of 28.6%. Only serum CEA was significantly associated with lower disease free and overall survival (P = 0.002 and P = 0.001, respectively). DISCUSSION AND CONCLUSION Serum CEA is shown to be significantly associated with poor prognosis for gastric cancer patients. Serum level of CA19-9 and high peritoneal CEA levels are significant predictors for positive peritoneal washing cytology and the development of peritoneal carcinomatosis, respectively. Therefore, the possible impact of serum and peritoneal tumor markers especially on the staging and prognosis of gastric cancer remains to be clarified by future studies.