Person: ZORLU, MEHMET
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Publication Metadata only Thorax computed tomography findings and anti-SARS-CoV-2 immunoglobulin G levels in polymerase chain reaction-negative probable COVID-19 cases.(2022-11-25) Yurtsever I.; Karatoprak C.; Sumbul B.; Kiskac M.; Tunc M.; Zorlu M.; Ogun H.; Durdu B.; Toluk O.; Cakirca M.; YURTSEVER, İSMAİL; KARATOPRAK, CUMALİ; SÜMBÜL, BİLGE; KISKAÇ, MUHARREM; TUNÇ, MUHAMMED; ZORLU, MEHMET; OGUN, HAMZA; DURDU, BÜLENT; TOLUK, ÖZLEM; ÇAKIRCA, MUSTAFAOBJECTIVE: This study aimed to evaluate the SARS-CoV-2 immunoglobulin G (IgG) levels after 6 months of polymerase chain reaction (PCR) negativebut assumed to be COVID-19 positive cases to investigate the relationship between IgG levels and thoracic computed tomography (CT) findings.METHODS: This was a single-center study that included patients whose PCR test results were negative at least three times using nasopharyngealswabs but had clinical findings of COVID-19 and thoracic CT findings compatible with viral pneumonia. Six months after discharge, the IgG antibodieswere analyzed. The cutoff value for negative and positive serology was defined as <1.4 (index S/C) and ≥1.4 (index S/C), respectively. In addition, thepatients were categorized according to their thoracic CT findings as high (typical) and low (atypical). Also, the patients were grouped into classes as<5% lung involvement versus ≥5% lung involvement.RESULTS: The patients’ mean age was 49.78±12.96 years. PCR was negative, but patients with COVID-19 symptoms who had SARS-CoV-2 IgGpositive were 81.9% (n=95). The antibody titer and lung involvement ≥5% were statistically significantly higher in SARS-CoV-2 IgG positive cases(p<0.001 and p=0.021). Age and chest CT findings were the risk factors for lung involvement (OR=1.08, p<0.001 and OR=2.19, p=0.010, respectively).CONCLUSION: This study is valuable because increasing severity (≥5%) of lung involvement appears to be associated with high and persistent IgGantibody titers. In probable cases of COVID-19, even if the PCR test is negative, high IgG titers 6 months after discharge can predict the rate of lungparenchymal involvement.Publication Open Access Determining the Frequency of Restless Legs Syndrome in the Adult Population(2024-10-01) KISKAÇ N.; ZORLU M.; ZORLU, MEHMETObjective: Restless legs syndrome (RLS) is a chronic disease that usually occurs in the legs, resulting in involuntary movement of the legs with uncomfortable sensations. RLS negatively affects the quality of life of individuals. In this study, it is aimed to increase awareness by determining the frequency of RLS in the adult population. Methods: The study was a descriptive and cross-sectional study. In the study, 565 individuals aged 18 and over participated. The data were collected online from individuals with the form of describing the personal characteristics of the individuals, the RLS Diagnostic Criteria Questionnaire, and the RLS Severity Rating Scale. IBM SPSS statistics 26.0 program was used in the analysis of the data. Results: In this study, the frequency of RLS was 17.5% and the severity score was 19.22 +/- 6.97 (moderate). The rate of admitting to a health institution due to the symptoms of individuals is 5.8%. In this study, the frequency of RLS was found to be significantly higher in those with diabetes, hypertension, age, and high body mass index. Conclusion: Although most of the participants in this study had symptoms of RLS, it was seen that they were not admitted to a health institution. If these individuals are not treated, their quality of life gets affected negatively, and this negatively affects the quality of health care. In order to increase the quality of health care, RLS should be screened especially in risky groups and treatment should be started in determined patients.