Person: DİNÇ, HARİKA ÖYKÜ
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Publication Metadata only Waning of SARS-CoV-2 Vaccine-Induced Immune Response over 6 Months in Peritoneal Dialysis Patients and the Role of a Booster Dose in Maintaining Seropositivity(2022-05-01T00:00:00Z) Murt, Ahmet; Dinc, HARİKA ÖYKÜ; Altiparmak, Mehmet Riza; Yalin, Serkan F.; Yadigar, Serap; Parmaksiz, Ergun; Kocazeybek, Bekir; Pekpak, Meltem; Ataman, Muveddet Rezzan; DİNÇ, HARİKA ÖYKÜIntroduction: Although lower than general population, newly developed SARS-CoV-2 vaccines generate immune responses in end-stage kidney disease patients. However, the persistence of immune responses in the long term is not known yet. This study aimed to evaluate humoral immune responses in peritoneal dialysis (PD) patients over 6 months and to analyze the effects of the booster dose. Methods: Humoral immune responses of PD patients were measured after initial SARS-CoV-2 vaccinations and after 6 months following initial vaccinations. Immune responses were compared between patients who received and did not receive booster doses. PD patients were compared with 41 hemodialysis (HD) patients and 61 healthy controls. Humoral immune responses were measured by a commercial test that detects antibodies toward the receptor-binding domain of the spike protein of SARS-CoV-2. Results: Twenty PD patients were evaluated over 6 months. The initial seropositivity rate was 90.9% with inactivated vaccine and 100% with mRNA vaccine. Seropositivity decreased to 44.4% after 6 months, and a booster dose helped in maintaining the 100% of seropositivity (p = 0.005). Magnitude of humoral response at the 6th month was also higher in patients who received the third dose (1,132.8 +/- 769.6 AU/mL vs. 400.0 +/- 294.6 AU/mL; p = 0.015). Among patients who did not receive the third dose, those who got mRNA vaccine could maintain higher seropositivity than others who got inactivated vaccine (75% vs. 40% for PD, 81.8% vs. 50% for HD). Seropositivity and antibody levels were similar for PD and HD patients after 6 months (p = 0.24 and 0.56) but lower than healthy controls (p = 0.0013). Conclusion: SARS-CoV-2 vaccine-induced antibody levels and seropositivity of PD patients significantly fall after 6 months. A booster dose after around 3 months following initial immunization might help in maintaining seropositivity.Publication Metadata only Risk factors influencing seroconversion after inactive SARS-CoV-2 vaccination in people living with obesity(2022-08-01T00:00:00Z) KARA, ZEHRA; Akcin, Rueveyda; DEMİR, Ahmet Numan; Dinc, Harika Oyku; KOCAZEYBEK, BEKİR SAMİ; YUMUK, VOLKAN DEMİRHAN; DİNÇ, HARİKA ÖYKÜIntroductionPublication Metadata only Retrospective Evaluation of Toxoplasma gondii, Rubella and Cytomegalovirus Seropositivity and Avidity Test Results in Patients Admitted to İU-C Cerrahpaşa Medical Faculty Hospital Between 2013-2018(2020-01-01T00:00:00Z) Demir, Esra; DİNÇ, HARİKA ÖYKÜ; Özbey, Doğukan; AKKUŞ, SEHER; ERGİN, SEVGİ; KOCAZEYBEK, BEKİR SAMİ; DİNÇ, HARİKA ÖYKÜPublication Metadata only BIOACTIVE COMPONENTS AND ANTIOXIDANT AND ANTIMICROBIAL ACTIVITY OF RHUS CORIARIA SPECIES OF SUMAC IN TURKEY(2022-02-18T00:00:00Z) Yüksel Mayda, Pelin; Polat, Silva; Büyükkılıç Altınbaşak, Betül; Dinç, Harika Öykü; Çalışkan, Reyhan; BÜYÜKKILIÇ ALTINBAŞAK, BETÜL; DİNÇ, HARİKA ÖYKÜPublication Metadata only The prevalence of periodontal pathogenic bacteria in atherosclerotic cardiovascular disease(2020-01-01T00:00:00Z) Gode, Safa; Sarp, Tevhide Z.; Saribas, Suat; Ergin, Sevgi; Kasnak, Gökhan; Dinc, HARİKA ÖYKÜ; Caliskan, Reyhan; Akkus, Seher; Tokman, Hrisi B.; Kocak, Banu T.; Demirci, Mehmet; Gareayaghi, Nesrin; Kirmusaoglu, Sahra; Tokman, Halit; Kocazeybek, Bekir; DİNÇ, HARİKA ÖYKÜPublication Metadata only BİR ÜNİVERSİTE HASTANESİNDE YATAN HASTALARDAİNFEKSİYON/KOLONİZASYON YÖNÜNDEN RİSK FAKTÖRLERİNİN DAĞILIMI(2017-03-22T00:00:00Z) KURT, AYKUT; DİNÇ, HARİKA ÖYKÜ; Küçük Aydın, Nida; BALKAN, İLKER İNANÇ; SALTOĞLU, NEŞE; cengiz, serpil; alisha, lütfiye; AYGÜN, GÖKHAN; DİNÇ, HARİKA ÖYKÜPublication Metadata only The role of adenovirus 36 as a risk factor in obesity: The first clinical study made in the fatty tissues of adults in Turkey(2015-03-01T00:00:00Z) Ergin, Sevgi; Altan, Eda; Pilanci, Ozgur; Sirekbasan, Serhat; Cortuk, Oguz; Cizmecigil, Utku; Ersin, Idris; Elbey, Huseyin; Dinc, HARİKA ÖYKÜ; Habip, Zafer; Turan, Nuri; Arinci, Atilla; Richt, Juergen A.; Goossens, Valere J.; Karakullukcu, Asiye; Kocak, Banu Tufan; Saribas, Suat; Koksal, Selcuk; Yilmaz, Huseyin; Kocazeybek, Bekir; DİNÇ, HARİKA ÖYKÜPublication Metadata only İ.Ü. Cerrahpaşa Tıp Fakültesi Tıbbi Mikrobiyoloji Seroloji/Elısa Ünitesine Gelen Serumlarda EBV Seropozitifliğinin Retrospektif Olarak 1,5 Yıllık Seroepidemiyolojik Değerlendirilmesi(2016-02-25T00:00:00Z) DİNÇ, HARİKA ÖYKÜ; bakır, esra; YÜKSEL MAYDA, PELİN; KOCAZEYBEK, BEKİR SAMİ; DİNÇ, HARİKA ÖYKÜ; YÜKSEL MAYDA, PELİNPublication Metadata only Diş Hekimliği Öğrencileri İçin Tıbbi Mikrobiyoloji(2022-01-01T00:00:00Z) DİNÇ, HARİKA ÖYKÜ; DİNÇ, HARİKA ÖYKÜPublication Metadata only Association of adenovirus 36 and gynecomastia development: A case-control study(2021-01-01T00:00:00Z) SİREKBASAN, SERHAT; DİNÇ, HARİKA ÖYKÜ; PİLANCI, ÖZGÜR; KESKİN, MELİKE; ALTAN TARAKCI, EDA; Çortuk, Oğuz; TURAN, NURİ; VELİDEDEOĞLU, MEHMET; KÖKSAL, SERDAR SELÇUK; Sarıbaş, Abdulkerim Suat; ERGİN, SEVGİ; YILMAZ, HÜSEYİN; KOCAZEYBEK, BEKİR SAMİ; DİNÇ, HARİKA ÖYKÜ