Person: DİNÇ, HARİKA ÖYKÜ
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Publication Metadata only The prevalence of periodontal pathogenic bacteria in atherosclerotic cardiovascular disease(2020-01-01T00:00:00Z) Gode, Safa; Sarp, Tevhide Z.; Saribas, Suat; Ergin, Sevgi; Kasnak, Gökhan; Dinc, HARİKA ÖYKÜ; Caliskan, Reyhan; Akkus, Seher; Tokman, Hrisi B.; Kocak, Banu T.; Demirci, Mehmet; Gareayaghi, Nesrin; Kirmusaoglu, Sahra; Tokman, Halit; Kocazeybek, Bekir; DİNÇ, HARİKA ÖYKÜPublication Metadata only The role of adenovirus 36 as a risk factor in obesity: The first clinical study made in the fatty tissues of adults in Turkey(2015-03-01T00:00:00Z) Ergin, Sevgi; Altan, Eda; Pilanci, Ozgur; Sirekbasan, Serhat; Cortuk, Oguz; Cizmecigil, Utku; Ersin, Idris; Elbey, Huseyin; Dinc, HARİKA ÖYKÜ; Habip, Zafer; Turan, Nuri; Arinci, Atilla; Richt, Juergen A.; Goossens, Valere J.; Karakullukcu, Asiye; Kocak, Banu Tufan; Saribas, Suat; Koksal, Selcuk; Yilmaz, Huseyin; Kocazeybek, Bekir; DİNÇ, HARİKA ÖYKÜPublication Metadata only Evaluating the effectiveness of anti-tuberculosis treatment by detecting Mycobacterium tuberculosis 85B messenger RNA expression in sputum(2020-01-01T00:00:00Z) Atahan, Ersan; Saribas, Suat; Demirci, Mehmet; Babalık, Aylin; Akkus, Seher; Balıkcı, Ahmet; Satana, Dilek; Ziver, Tevhide; Dinc, HARİKA ÖYKÜ; Keskin, Melike; Ozbey, Dogukan; Kocak, Banu Tufan; Gareayaghi, Nesrin; Kirmusaoglu, Sahra; Tokman, Hrisi Bahar; Kocazeybek, Bekir; DİNÇ, HARİKA ÖYKÜPublication Metadata only Helicobacter pylori-miRNA interaction in gastric cancer tissues: First prospective study from Turkey(2019-01-01T00:00:00Z) Demiryas, Suleyman; Kocazeybek, Bekir; Demirci, Mehmet; Caliskan, Reyhan; Kepil, Nuray; Uysal, Hayriye Kirkoyun; Dinc, HARİKA ÖYKÜ; Saribas, Suat; Ergin, Sevgi; Erzin, Yusuf; Tasci, İhsan; Erdamar, Sibel; Demirdag, Cetin; Tokman, Hrisi Bahar; DİNÇ, HARİKA ÖYKÜPublication Metadata only Problems encountered in conventional HIV 1/2 algorithms: Lack of necessity for immunoblot assays to confirm repeated ELISA reactive results(2018-06-01T00:00:00Z) Yuksel, Pelin; Saribas, Suat; Kuskucu, Mert; Mutcali, Sibel Islak; Kosan, Erdogan; Habip, Zafer; Demirci, Mehmet; Kara, Eda Salihoglu; Birinci, Ilhan; Caliskan, Reyhan; Dinc, HARİKA ÖYKÜ; Midilli, Kenan; Ziver, Tevhide; Kocazeybek, Bekir; YÜKSEL MAYDA, PELİN; DİNÇ, HARİKA ÖYKÜBackground: The use of conventional (serologically based) HIV 1/2 diagnostic algorithms has become controversial in recent years.Publication Open Access Diagnostic performance of the RT-qPCR method targeting 85B mRNA in the diagnosis of pulmonary Mycobacterium tuberculosis infection(2018-09-01T00:00:00Z) Demirci, Mehmet; Saribas, Suat; Ozer, Nigar; TOPRAK, Sezer; CAGLAR, Emel; ORTAKOYLU, Gonenc; Yuksel, PELİN; Ayaz, Gulsel; Tokman, Hrisi B.; Uysal, Omer; Dinc, HARİKA ÖYKÜ; ZİVER, Tevhide; Kocazeybek, Bekir; YÜKSEL MAYDA, PELİN; UYSAL, ÖMER; DİNÇ, HARİKA ÖYKÜBackground: Several nucleic acid amplification techniques (IS6110, 16S rRNA, and 85B mRNA) were developed for the rapid, direct detection of Mycobacterium tuberculosis. We aimed to assess the diagnostic performance of 85B mRNA-based RT-qPCR by comparing with the real-time PCR COBAS TagMan MTB Kit while using the BACTEC MGIT 960 method as the gold standard.Publication Metadata only Evaluation of Adenovirus-36 (Ad-36) antibody seropositivity and adipokine levels in obese children(2017-07-01T00:00:00Z) Kocazeybek, Bekir; Dinc, HARİKA ÖYKÜ; Ergin, Sevgi; Saribas, Suat; Ozcabi, Bahar Taskm; Cizmecigil, Utku; Altan, Eda; Atalik, Keyser; Yuksel, Pelin; Taner, Zeynep; Karakullukcu, Asiye; Sirekbasan, Serhat; Turan, Nuri; Cagatay, Penbe; Imamova, Nergiz; Evliyaoglu, Olcay; Yilmaz, Huseyin; DİNÇ, HARİKA ÖYKÜ; YÜKSEL MAYDA, PELİNAdenovirus 36 (Ad-36) has recently been suggested as a possible contributor to the current obesity epidemic. The aim of this study was to investigate the prevalence of Ad-36 antibodies in obese children, as well as investigate the role of serum leptin and lipid levels in Ad-36-obesity. Seventy-one obese children and 62 non-obese children were included as the patient group (PG), including the healthy control group (HCG), respectively. Simultaneously, Ad-36 antibodies and adipokine levels were assessed with serum neutralization assays (SNA) and ELISA. Ad-36 antibody was detected in 9 patients (12.7%) and 1 patient (1.6%) in both the PG and HCG, respectively, while a significant difference was detected between groups (p < 0.05). Although serum LDL, total cholesterol, triglycerides and leptin levels were detected significantly higher, adiponectin level was detected paradoxically lower in the PG. However, a significant difference was not detected for lipids and leptin levels; adiponectin levels were found to be significantly lower in Ad-36 antibody-positive PG (p < 0.05).Publication Metadata only Travel-associated infections caused by unusual serogroups of Legionella pneumophila identified using Legionella BIOCHIP slides in Turkey and Iraq(2016-05-01T00:00:00Z) Kocazeybek, Bekir S.; Yuksel, Pelin; Keskin, Dilek; Sheikh, Suhail; Habip, Zafer; Yavuzer, Serap Sahin; Caliskan, Reyhan; Altun, Yagiz Meric; Kuskucu, Mert; Cengiz, Mahir; Dinc, HARİKA ÖYKÜ; Karakullukcu, Asiye; Ergin, Sevgi; Saribas, Suat; Yilmaz, Nail; Tokman, Hrisi Bahar; YÜKSEL MAYDA, PELİN; DİNÇ, HARİKA ÖYKÜBackground: Although Legionella pneumophila serogroup 1 is the common disease causing serogroup, rare serogroups can also may cause legionellosis. A 54-year-old male patient (index case) reported that he had been on a religious trip (for visiting, tomb of Ali, which is important for Shias) to Iraq with a large group (50 shia pilgrims from Kars city of Turkey) two weeks prior to admission. Due to civil war, the hotel where the patient stayed in Iraq lacked proper hygiene. A large number of people in the travel group were experiencing the same symptoms. Other five cases were 2 males (ages; 50, 45) and 3 females including the wife of the index case (ages; 50, 28, 27).Publication Metadata only Patterns of epiya motifs among cagA-positive Helicobacter pylori strains: A case–control study in a turkish population with eurasian geographical features(2015-10-01T00:00:00Z) Kocazeybek, Bekir Sami; Caliskan, Reyhan; Cetin, Sibel Erdamar; Ergin, Sevgi; Kuskucu, Mert; Kepil, Nuray; Dinc, HARİKA ÖYKÜ; Erzin, Yusuf Ziya; Saribas, Suat; Tokman, Hrisi Bahar; Kalayci, Fatma; Akgul, Ozer; Yuksel, Pelin; Karakullukcu, Asiye; Ziver, Tevhide; Sirekbasan, Serhat; Caglar, Erkan; Bal, Kadir; DİNÇ, HARİKA ÖYKÜ; YÜKSEL MAYDA, PELİNGeographical variation in the frequency of various gastroduodenal pathologies was shown to be related to the geographical diversity of H. pylori CagA Glu-Pro-lle-Tyr-Ala (EPIYA) patterns. We examined the EPIYA patterns of H. pylori and the association of EPIYA patterns with gastric cancer (GC) for the first time, to the best of our knowledge, in Turkey. The patient group (PG) contained 60 patients [38 GC and 22 duodenal ulcer (DU) patients]. The control group (CG) was 110 individuals [94 gastritis patients and 16 persons with a normal gastrointestinal system (NGIS)]. Specific primers were used for the detection of cagA including empty-site-positive and EPIYA-A, -B, -C, -D PCR. Bands of EPIYA-A, -B, -C were confirmed by DNA sequencing. One hundred and forty-two (83.5 %) strains [60 in the PG (38 GC, 22 DU), 82 in the CG (72 gastritis, 10 NGIS)] were positive for the cagA gene. EPIYA-C with multiple repeats was detected in 34 (23.9 %) strains, and 22 (64.7 %) were from GC patients. EPIYA-C with one repeat was detected in 89 (62.7 %) strains, and 54 (60.7 %) were from gastritis patients. EPIYT was detected in 10 strains, and EPIYA-D was not detected. The number of EPIYA-C with multiple repeats was significantly higher for the PG than for the CG (P<0.0001). In GC patients, the number of EPIYA-C with multiple repeats was significantly higher than one repeat (P<0.0001). In conclusion, our study showed that multiple EPIYA-C repeats increases the GC risk by 30.6-fold and the DU risk by 8.9-fold versus the CG. This indicates that Western-type H. pylori strains in Turkey have similar EPIYA motifs to those of neighbouring countries and Western populations.