Person: İNCE, ALİ TÜZÜN
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Publication Metadata only Early prediction of acute necrotizing pancreatitis by artificial intelligence: a prospective cohort-analysis of 2387 cases.(2022-05-12T00:00:00Z) Kiss, Szabolcs; Kiss, Szabolcs; Pintér, József; Molontay, Roland; Nagy, Marcell; Farkas, Nelli; Farkas, Nelli; Sipos, Zoltán; Sipos, Zoltán; Pecze, László; Pecze, László; Földi, Mária; Földi, Mária; Vincze, Áron; Vincze, Áron; Takács, Tamás; Takács, Tamás; Halász, Adrienn; Halász, Adrienn; Faluhelyi, Nándor; Faluhelyi, Nándor; Farkas, Orsolya; Farkas, Orsolya; Váncsa, Szilárd; Váncsa, Szilárd; Erőss, Bálint; Erőss, Bálint; Párniczky, Andrea; Párniczky, Andrea; Hegyi, Péter; Hegyi, Péter; Fehérvári, Péter; Fehérvári, Péter; Czakó, László; Czakó, László; Izbéki, Ferenc; Izbéki, Ferenc; Boros, Eszter; Boros, Eszter; Hamvas, József; Hamvas, József; Varga, Márta; Varga, Márta; Mickevicius, Artautas; Mickevicius, Artautas; Nagy, Rita; Nagy, Rita; Bunduc, Stefania; Bunduc, Stefania; Hegyi, Péter Jenő; Hegyi, Péter Jenő; Márta, Katalin; Márta, Katalin; Borka, Katalin; Borka, Katalin; Doros, Attila; Doros, Attila; Hosszúfalusi, Nóra; Hosszúfalusi, Nóra; Zubek, László; Zubek, László; Molnár, Zsolt; Molnár, Zsolt; Szentesi, Andrea; Szentesi, Andrea; Bajor, Judit; Gódi, Szilárd; Sarlós, Patrícia; Czimmer, József; Szabó, Imre; Pár, Gabriella; Illés, Anita; Hágendorn, Roland; Németh, Balázs Csaba; Kui, Balázs; Illés, Dóra; Gajdán, László; Dunás-Varga, Veronika; Fejes, Roland; Papp, Mária; Vitális, Zsuzsanna; Novák, János; Török, Imola; Macarie, Melania; Ramírez-Maldonado, Elena; Sallinen, Ville; Galeev, Shamil; Bod, Barnabás; Ince, ALİ TÜZÜN; Pécsi, Dániel; Varjú, Péter; Juhász, Márk Félix; Ocskay, Klementina; Mikó, Alexandra; Szakács, Zsolt; İNCE, ALİ TÜZÜNPublication Metadata only MUCINOUS PANCREATIC CYST SUBGROUPS: THE ROLE OF CYST FLUID VISCOSITY AND CYST MORPHOLOGY IN DIFFERENTIATION(2021-06-01T00:00:00Z) Koker, Ibrahim H.; Elagoz, Sahende; Malya, Fatma U.; Kiremitci, Sercan; Ince, ALİ TÜZÜN; Senturk, Hakan; İNCE, ALİ TÜZÜNPublication Open Access Evidence for diagnosis of early chronic pancreatitis after three episodes of acute pancreatitis: a cross-sectional multicentre international study with experimental animal model.(2021-01-14T00:00:00Z) Hegyi, Péter J; Soós, Alexandra; Tóth, Emese; Ébert, Attila; Venglovecz, Viktória; Márta, Katalin; Mátrai, Péter; Mikó, Alexandra; Bajor, Judit; Sarlós, Patrícia; Vincze, Áron; Halász, Adrienn; Izbéki, Ferenc; Szepes, Zoltán; Czakó, László; Kovács, György; Papp, Mária; Dubravcsik, Zsolt; Varga, Márta; Hamvas, József; Németh, Balázs C; Macarie, Melania; Ince, ALİ TÜZÜN; Bordin, Dmitry S; Dubtsova, Elena A; Kiryukova, Mariya A; Khatkov, Igor E; Bideeva, Tanya; Mickevicius, Artautas; Ramírez-Maldonado, Elena; Sallinen, Ville; Erőss, Bálint; Pécsi, Dániel; Szentesi, Andrea; Párniczky, Andrea; Tiszlavicz, László; Hegyi, Péter; İNCE, ALİ TÜZÜNChronic pancreatitis (CP) is an end-stage disease with no specific therapy; therefore, an early diagnosis is of crucial importance. In this study, data from 1315 and 318 patients were analysed from acute pancreatitis (AP) and CP registries, respectively. The population from the AP registry was divided into AP (n = 983), recurrent AP (RAP, n = 270) and CP (n = 62) groups. The prevalence of CP in combination with AP, RAP2, RAP3, RAP4 and RAP5 + was 0%, 1%, 16%, 50% and 47%, respectively, suggesting that three or more episodes of AP is a strong risk factor for CP. Laboratory, imaging and clinical biomarkers highlighted that patients with RAP3 + do not show a significant difference between RAPs and CP. Data from CP registries showed 98% of patients had at least one AP and the average number of episodes was four. We mimicked the human RAPs in a mouse model and found that three or more episodes of AP cause early chronic-like morphological changes in the pancreas. We concluded that three or more attacks of AP with no morphological changes to the pancreas could be considered as early CP (ECP).The new diagnostic criteria for ECP allow the majority of CP patients to be diagnosed earlier. They can be used in hospitals with no additional costs in healthcare.Publication Metadata only Inflammatory bowel disease does not alter the clinical features and the management of acute pancreatitis: A prospective, multicentre, exact-matched cohort analysis(2022-01-01T00:00:00Z) Dohos, Dóra; Farkas, Nelli; Váradi, Alex; Erőss, Bálint; Párniczky, Andrea; Szentesi, Andrea; Hegyi, Péter; Sarlós, Patrícia; Czakó, László; Boros, Eszter; Hussein, Tamás; Márta, Katalin; Borka, Katalin; Doros, Attila; Hosszúfalusi, Nóra; Zubek, László; Molnár, Zsolt; Váncsa, Szilárd; Nagy, Rita; Bunduc, Stefania; Földi, Mária; Faluhelyi, Nándor; Farkas, Orsolya; Vincze, Áron; Kui, Balázs; Izbéki, Ferenc; Hamvas, József; Papp, Mária; Varga, Márta; Török, Imola; Mickevicius, Artautas; Maldonado, Elena Ramirez; Sallinen, Ville; Ince, ALİ TÜZÜN; Galeev, Shamil; Poropat, Goran; Stimac, Davor; Litvin, Andrey; Ozola-Zalite, Imanta; Pukitis, Aldis; Zadorozhna, Kristina; Gyökeres, Tibor; İNCE, ALİ TÜZÜN© 2022 The AuthorsObjective and aims: Acute pancreatitis in inflammatory bowel disease occurs mainly as an extraintestinal manifestation or a side effect of medications. We aimed to investigate the prognostic factors and severity indicators of acute pancreatitis and the treatment of patients with both diseases. Design: We performed a matched case-control registry analysis of a multicentre, prospective, international acute pancreatitis registry. Patients with both diseases were matched to patients with acute pancreatitis only in a 1:3 ratio by age and gender. Subgroup analyses were also carried out based on disease type, activity, and treatment of inflammatory bowel disease. Results: No difference in prognostic factors (laboratory parameters, bedside index of severity in acute pancreatitis, imaging results) and outcomes of acute pancreatitis (length of hospitalization, severity, and local or systemic complications) were detected between groups. Significantly lower analgesic use was observed in the inflammatory bowel disease population. Antibiotic use during acute pancreatitis was significantly more common in the immunosuppressed group than in the non-immunosuppressed group (p = 0.017). However, none of the prognostic parameters or the severity indicators showed a significant difference between any subgroup of patients with inflammatory bowel disease. Conclusion: No significant differences in the prognosis and severity of acute pancreatitis could be detected between patients with both diseases and with pancreatitis only. The need for different acute pancreatitis management is not justified in the coexistence of inflammatory bowel disease, and antibiotic overuse should be avoided.Publication Metadata only COMPARISON OF ENDOSCOPIC ULTRASOUND-GUIDED COIL INJECTION WITH AND WITHOUT CYANOACRYLATE INJECTION FOR GASTRIC VARICES(2022-06-01T00:00:00Z) Seven, Gulseren; Musayeva, Gunel; Seven, Ozden Ozluk; Herdan, Emre; Ince, ALİ TÜZÜN; Senturk, Hakan; İNCE, ALİ TÜZÜNPublication Metadata only Comparison of endoscopic ultrasound-guided coil deployment with and without cyanoacrylate injection for gastric varices.(2022-05-04T00:00:00Z) Seven, Gulseren; Musayeva, Gunel; Seven, Ozden Ozluk; Herdan, Emre; Ince, ALİ TÜZÜN; Senturk, Hakan; İNCE, ALİ TÜZÜNPublication Metadata only Alcohol consumption and smoking dose-dependently and synergistically worsen local pancreas damage.(2022-01-19T00:00:00Z) Szentesi, Andrea; Farkas, Nelli; Sipos, Zoltán; Mátrai, Péter; Vincze, Áron; Izbéki, Ferenc; Párniczky, Andrea; Hegyi, Péter; Erőss, Bálint; Hegyi, Péter Jenő; Váncsa, Szilárd; Nagy, Rita; Márta, Katalin; Ocskay, Klementina; Juhász, Márk Félix; Imrei, Marcell; Földi, Mária; Kiss, Szabolcs; Németh, Balázs Csaba; Takács, Tamás; Czakó, László; Gódi, Szilárd; Bajor, Judit; Sarlós, Patrícia; Gajdán, László; Papp, Mária; Hamvas, József; Varga, Márta; Macarie, Melania; Török, Imola; Novák, János; Mickevicius, Artautas; Maldonado, Elena Ramirez; Galeev, Shamil; Sallinen, Ville; Bod, Barnabás; Ince, ALİ TÜZÜN; Nagy, Tamás; Faluhelyi, Nándor; Gede, Noémi; Bunduc, Stefania; Hussein, Tamás; Lipp, Mónika; Németh, Anna; Urbán, Orsolya; Tarján, Dorottya; Tóth, Simon; Pécsi, Dániel; Varjú, Péter; Zádori, Noémi; İNCE, ALİ TÜZÜN