Person: MAYADAĞLI, ALPASLAN
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Publication Metadata only The effect of tumor size on overall survival in patients with pT3 gastric cancer: experiences from 3 centers.(2010-01-01T00:00:00Z) BILICI, A; UYGUN, K; Seker, MESUT; USTAALIOĞLU, BB; ALIUSTAOGLU, M; TEMIZ, S; AKSU, G; GEZEN, C; YAVUZER, D; KAYA, S; SALEPCI, T; MAYADAGLI, ALPASLAN; GUMUS, M; ŞEKER, MESUT; MAYADAĞLI, ALPASLANPublication Metadata only Measurement of Strain Imaging, Troponin-I and Brain Natriuretic Peptide Levels in Radiotherapy-Induced Cardiac Injury(2016-01-01T00:00:00Z) Ekici, Kemal; Cakal, Beytullah; Baydar, Onur; MAYADAĞLI, Alpaslan; Cakal, Sinem D.; Karaca, Oguz; Omaygenc, M. Onur; MAYADAĞLI, ALPASLANRadiotherapy (RT) of the thorax can damage the pericardium, myocardium, heart valves, and coronary vessels, with the pericardium being the most frequently damaged. The objectives of this study were to evaluate RT-induced left ventricular dysfunction and myocardial injury by measuring cardiac biomarkers, troponin I (TnI) and brain natriuretic peptide (BNP), as well as determin cardiotoxicity and early signs of cardiovascular dysfunction using strain rate imaging (SRI) prior to and following RT. This study included 35 patients diagnosed with thoracic malignancy between January 2011 and October 2013. Of the 35 patients, 22 had left-sided lung cancer and 13 had left-sided breast cancer. SRI was performed and TnI and BNP levels were measured prior to and following RT. A total radiation dose of 40-60 Gy (mean, 54.9 +/- 8.9 Gy) was applied in lung cancer patients and 50-60 Gy (mean, 51.6 +/- 4.9 Gy) was applied in breast cancer patients. No significant difference was observed in TnI or BNP levels prior to and one month following RT. The left ventricular ejection fraction (LVEF) did not differ prior to or after the first month of RT. However, lower right ventricular strain (RVS) and left ventricular strain (LVS) SRI values were detected within the first month following RT. From the results of this study, we conclude that SRI is a sensitive method to detect RT-induced changes in cardiac function that are not typically detected by conventional echocardiographic methods and cardiac biomarkers.Publication Metadata only S 31: Radyasyonun Kullanım Alanlarındaki Çalışan Dozları ve stokastik Etkiye Neden Olabilecek Radyasyon için Deneysel bir Çalışma(2017-10-28) ERİŞ, ALİ HİKMET; KIZILTAN, HURİYE ŞENAY; MAYADAĞLI, ALPASLAN; KABLAN, Ozgur; GÜLBAHAR, İBRAHİM; ERİŞ, ALİ HİKMET; KIZILTAN, HURİYE ŞENAY; MAYADAĞLI, ALPASLAN; KABLAN, ÖZGÜRPublication Metadata only Prognostic significance of protein kinase B/Akt pathway in patients with non-small cell lung cancer(2014-01-01T00:00:00Z) Mayadagli, Alpaslan; Gul, Sule Karabulut; Bilici, Ahmet; Oruc, Ahmet Fatih; Kocak, Mihriban; Ozkan, Alper; Aksu, Atinc; Barisik, Nagehan Ozdemir; Gumus, Mahmut; MAYADAĞLI, ALPASLANPurpose: Akt, also known as protein kinase B (PKB), is an intracellular signal transduction protein activated by growth hormones. PKB/Akt is frequently activated in a variety of cancer types, but its role in the development and progression of lung cancer has not been completely elucidated yet. The aim of the present study was to determine the prognostic value of PKB/Akt in non-small cell lung cancer (NSCLC).Publication Metadata only COULD PRETREATMENT PET-CT STANDART UPTAKE VALUES HAVE A ROLE IN THE RESPONSE TO TREATMENT AND THE SURVIVAL IN PATIENTS WITH SMALL CELL LUNG CANCER?(2013-11-01T00:00:00Z) Aydin, Kubra; Odabas, Hatice; Seker, Mesut; Korkmaz, Taner; Yasar, Nurgul; Sener, Nur; Aydin, Dincer; Ercelep, Ozlem; Yuksel, Sinemis; Mert, Aslihan G.; Aliustaoglu, Mehmet; Mayadagli, Alpaslan; Dane, Faysal; Gumus, Mahmut; MAYADAĞLI, ALPASLANPublication Metadata only Efficacy of stereotactic radiotherapy as salvage treatment for recurrent malignant gliomas(2014-10-01T00:00:00Z) Ekici, Kemal; Ozsekee, Naciye; Mayadagli, Alpaslan; Kocak, Mihriban Erdogan; Olmezoglu, Ali; MAYADAĞLI, ALPASLANPurpose: To evaluate the efficacy and toxicity of CyberKnife stereotactic radiotherapy (SRT) for recurrent glial tumors previously treated with high-dose radiotherapy.Publication Metadata only Thermal and Biochemical Effects of Low Level Electromagnetic Radiation on Rat Brains and Bodies(2014-06-01) KIZILTAN, HURİYE ŞENAY; ERİŞ, ALİ HİKMET; MAYADAĞLI, ALPASLAN; GÜNEŞ BAYIR, AYŞE; YAGCI, B; TAŞPINAR, ÖZGÜR; AYDIN, TEOMAN; TRABZON, M; KIZILTAN, HURİYE ŞENAY; ERİŞ, ALİ HİKMET; MAYADAĞLI, ALPASLAN; GÜNEŞ BAYIR, AYŞE; AYDIN, TEOMANPublication Metadata only Beyin metastazlı hastalarda gamma knife radiocerrahisinin ve tüm beyi ışınlamasının immün sistem ilişkili proteinlwer üzerine etkilerinin incelenmesi(2018-04-20) KOÇYİĞİT, ABDURRAHİM; HATİBOĞLU, MUSTAFA AZİZ; GÜLER, ERAY METİN; nallı, arife; akdur, kerime; şakarcan, ayten; özek, erdinç; BULUT, HURİ; MAYADAĞLI, ALPASLAN; SEYİTHANOĞLU, MEHMET HAKAN; HATİBOĞLU, MUSTAFA AZİZ; KOÇYİĞİT, ABDÜRRAHİM; GÜLER, ERAY METİN; MAYADAĞLI, ALPASLAN; SEYİTHANOĞLU, MEHMET HAKANPublication Metadata only İnoperatif Pankreas Kanserinde Nigella Sativanın Kemoterapi ve Radyoterapinin Duyarlığını Artırıcı Etkisi(2016-03-23) KIZILTAN, HURİYE ŞENAY; TÜRKDOĞAN, KÜRŞAT; MAYADAĞLI, ALPASLAN; KIZILTAN, HURİYE ŞENAY; MAYADAĞLI, ALPASLANPublication Metadata only Salvage Chemoradiation therapy for Loco-regional Recurrence After Adjuvant Gemcitabine in Patients With Resected Pancreatic Adenocarcinoma(2012-11-01T00:00:00Z) Gemici, C.; Yaprak, G.; Tepetam, H.; Mayadagli, Alpaslan; MAYADAĞLI, ALPASLAN