Person: ZEYBEK, RAHMİ
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Publication Metadata only Altered expression of micro-RNA 199a and increased levels of cardiac SIRT1 protein are associated with the occurrence of atrial fibrillation after coronary artery bypass graft surgery(2016-05-01T00:00:00Z) YAMAÇ, AYLİN HATİCE; Kucukbuzcu, Sitki; OZANSOY, MEHMET; Gok, Ozlem; Oz, Kursat; Erturk, Mehmet; Yilmaz, Emre; Ersoy, Burak; ZEYBEK, RAHMİ; Goktekin, Omer; Kilic, Ulkan; YAMAÇ, AYLİN HATİCE; ZEYBEK, RAHMİBackground: Postoperative atrial fibrillation (POAF) is a potentially life-threatening complication after coronary artery bypass graft (CABG) surgery. The expression of the cardioprotective SIRT1 protein with its antioxidant activity is increased in cardiac tissue of patients suffering from POAF. So far, information is lacking about the relationship between SIRT1 regulating micro RNAs (miRs), SIRT1 protein and the occurrence of POAF.Publication Open Access Valve sparing surgery in an adult patient with dextrocardia and annuloaortic ectasia(2016-01-01) Zeybek, RAHMİ; Bacaksiz, AHMET; Sharifov, RASUL; SEVGILI, Emrah; Ay, YASİN; ZEYBEK, RAHMİ; BACAKSIZ, AHMET; SHARIFOV, RASUL; AY, YASİNWe report the case of a patient with situs inversus totalis, annuloaortic ectasia complicated by aortic insufficiency and mitral regurgitation which induced congestive heart failure. Both valvular lesions were repaired physiologically using aortic root sparing Yacoub 'remodeling' technique and mitral ring annuloplasty. Valve sparing techniques can be used effectively even in patients with complicated clinical scenarios (like dextrocardia and annuloaortic ectasia) to avoid the potential risks related to prosthetic valve implantation and lifelong anticoagulation therapy.Publication Metadata only Red cell distribution width predicts new-onset atrial fibrillation after coronary artery bypass grafting(2013-06-01T00:00:00Z) Ertas, Gokhan; AYDIN, CEMALETTİN; Sonmez, Osman; Erdogan, Ercan; Turfan, Murat; Tasal, Abdurrahman; BACAKSIZ, AHMET; Vatankulu, Mehmet Akif; Uyarel, Huseyin; Ergelen, Mehmet; ZEYBEK, RAHMİ; Goktekin, Omer; AYDIN, CEMALETTİN; BACAKSIZ, AHMET; ZEYBEK, RAHMİIntroduction. Red cell distribution width (RDW) has been associated with poor outcomes in patients with cardiovascular diseases. However, little is known about the role of RDW in prediction of new-onset atrial fibrillation (AF) after coronary artery bypass grafting (CABG). We aimed to investigate the relation between the RDW and postoperative AF in patients undergoing CABG. Methods. A total of 132 patients undergoing nonemergency CABG were included in the study. Patients with previous atrial arrhythmia or requiring concomitant valve surgery were excluded. We retrospectively analyzed 132 consecutive patients (mean age, 60.55 +/- 9.5 years; 99 male and 33 female). The RDW level was determined preoperatively and on postoperative Day 1. Results. Preoperative RDW levels were significantly higher in patients who developed AF than in those who did not (13.9 +/- 1.4 vs. 13.3 +/- 1.2, p = 0.03). There was not any correlation between postoperative RDW levels and AF. Using a cutpoint of 13.45, the preoperative level correlated with the incidence of AF with a sensitivity of 61% and specificity of 60%. Conclusion. Preoperative RDW level predicts new-onset AF after CABG in patients without histories of AF.Publication Metadata only A rare complication of pre-Eisenmenger patent ductus arteriosus: Pulmonary artery dissection(2013-01-01T00:00:00Z) AY, YASİN; KAHRAMAN AY, Nuray; AYDIN, CEMALETTİN; KARA, İBRAHİM; ZEYBEK, RAHMİ; AY, YASİN; KAHRAMAN AY, NURAY; AYDIN, CEMALETTİN; ZEYBEK, RAHMİINTRODUCTION: Pulmonary artery dissection associated with patent ductus arteriosus is usually seen in patients with pulmonary hypertension and Eisenmenger-s syndrome. This paper presents a case with pre-Eisenmenger patent ductus arteriosus complicated by pulmonary artery dissection, and explains how she was surgically treated.Publication Open Access Effects of ischemic preconditioning and iloprost on myocardial ischemia-reperfusion damage in rats(2013-01-01) Ay, YASİN; Kara, Ibrahim; Aydin, CEMALETTİN; TEKER, Melike Elif; Senol, Serkan; Inan, BEKİR; BASEL, Halil; Uysal, Omer; Zeybek, RAHMİ; AY, YASİN; AYDIN, CEMALETTİN; KAHRAMAN AY, NURAY; İNAN, BEKİR; UYSAL, ÖMER; ZEYBEK, RAHMİThis study investigates the effects of cardiac ischemic preconditioning and iloprost on reperfusion damage in rats with myocardial ischemia/reperfusion. 38 male Wistar Albino rats used in this study were divided into 5 groups. The control group (Group 1) (n=6), ischemia/reperfusion (IR) group (Group 2) (n=8), cardiac ischemic preconditioning (CIP) group (Group 3) (n=8), iloprost (ILO) group (Group 4) (n=8), and cardiac ischemic preconditioning + iloprost (CIP+ILO) group (Group 5) (n=8). Pre-ischemia, 15 minutes post-ischemia, 45 minutes post-reperfusion, mean blood pressure (MBP), and heart rates (HR) were recorded. The rate-pressure product (RPP) was calculated. Post-reperfusion plasma creatine kinase-MB (CK-MB), lactate dehydrogenase (LDH), troponin (cTn) vlaues, and infarct size/area at risk (IS/AAR) were calculated from myocardial tissue samples. Arrhythmia and ST segment elevations were evaluated during the ischemia and reperfusion stages. Although the MBP, HR, RPP values, biochemical parameters of CK-MB and LDH levels, IS/AAR rates, ST segment elevation values were found to be similar in CIP and CIP+ILO groups and the IR and ILO groups (p>0.05), CIP-containing group values had a positively meaningful difference (p<0.05) compared with the IR and ILO group. While mild-moderate findings of damage were observed in Group 3 and Group 5, severely findings of damage were releaved in Group 2 and Group 4. The arrhythmia score of the ILO group was meaningfully lower (F: 41.4, p<0.001) than the IR group. We can conclude that the effects of myocardial reperfusion damage can be reduced by cardiac ischemic preconditioning, intravenous iloprost reduced the incidence of ventricular arrhythmia associated with reperfusion, and its use with CIP caused no additional changes.Publication Metadata only Transposition of the great arteries,secundum atrial septal defect,and dextrocardia with systemic cardiac valve insufficiency.(2012-11-08T00:00:00Z) BAŞEL, HALİL; AYDIN, CEMALETTİN; AY, YASİN; İNAN, BEKİR; Teker, Melike elif; TÜRKKOLU, ŞEVKET TUNA; ZALLOUM, Raed nj; ZEYBEK, RAHMİ; AYDIN, CEMALETTİN; AY, YASİN; İNAN, BEKİR; TÜRKKOLU, ŞEVKET TUNA; ZEYBEK, RAHMİPublication Metadata only Splenik arter anevrizmaları:12 hastalık tecrübelerimiz(2012-11-08T00:00:00Z) İNAN, BEKİR; teker, Melike elif; AYDIN, CEMALETTİN; AY, YASİN; BAŞEL, HALİL; ZEYBEK, RAHMİ; İNAN, BEKİR; AYDIN, CEMALETTİN; AY, YASİN; ZEYBEK, RAHMİPublication Metadata only Ischaemic mitral regurgitation: The effects of ring annuloplasty and suture annuloplasty repair techniques on left ventricular re-remodeling(2013-01-01T00:00:00Z) AYDIN, CEMALETTİN; Kara, Ibrahim; AY, YASİN; İNAN, BEKİR; Basel, Halil; Yanartas, Mehmet; ZEYBEK, RAHMİ; AYDIN, CEMALETTİN; AY, YASİN; İNAN, BEKİR; ZEYBEK, RAHMİObjective: To examine the mid-term results of patients on whom a coronary revascularization as well as a mitral ring and suture annuloplasty have been performed due to coronary artery disease (CAD) and ischaemic mitral regurgitation (IMR).Publication Open Access Comparison of the Health Related Quality of Life of Patients Following Mitral Valve Surgical Procedures in the 6-Months Follow-up: A Prospective Study(2013-04-01T00:00:00Z) AY, YASİN; KARA, İBRAHİM; AYDIN, CEMALETTİN; KAHRAMAN AY, Nuray; İNAN, BEKİR; Basel, Halil; ZEYBEK, RAHMİ; AY, YASİN; AYDIN, CEMALETTİN; KAHRAMAN AY, NURAY; İNAN, BEKİR; ZEYBEK, RAHMİPurpose: The aim of the present study is to evaluate the health-related quality of life of the patients who underwent mitral valve repair (MvRp) and mitral valve replacement (MVR).