Person: AKBULUT, HABİB
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Publication Metadata only Systematic versus cognitive targeted biopsy: evaluation of parameters related to clinically significant prostate cancer and comparison of detection rates(2022-10-01) Ersöz C.; İlktaç A.; Kalkan S.; Kayalı Y.; Akbulut H.; Toprak H.; Doğan B.; ERSÖZ, CEVPER; İLKTAÇ, ABDULLAH; KALKAN, SENAD; AKBULUT, HABİB; TOPRAK, HÜSEYİN; DOĞAN, BAYRAMPublication Metadata only The Success of Pyeloplasty in Adult Patients with Ureteropelvic Junction Obstruction(2022-12-01) İLKTAÇ A.; ERSÖZ C.; DOĞAN B.; AKBULUT H.; İLBEY Y. Ö.; İLKTAÇ, ABDULLAH; ERSÖZ, CEVPER; DOĞAN, BAYRAM; AKBULUT, HABİB; İLBEY, YUSUF ÖZLEMPublication Metadata only The effect of post-treatment PSA change and multiparametric prostate MRI findings in the detection of prostate cancer in patients receiving antibiotics due to PSA elevation(2020-07-24T00:00:00Z) Kayalı, Yunus; Doğan, Bayram; İlktaç, Abdullah; Ersöz, Cevper; Akçay, Muzaffer; Gevher, Fatih; Akbulut, Habib; Balbay, Mevlana Derya; DOĞAN, BAYRAM; İLKTAÇ, ABDULLAH; ERSÖZ, CEVPER; AKÇAY, MUZAFFER; GEVHER, FATİH; AKBULUT, HABİBPublication Metadata only Expression of mesenchymal stem cell markers of human adipose tissue surrounding the vas deferens(2012-04-01T00:00:00Z) Akbulut, HABİB; Cuce, Gokhan; Aktan, Tahsin Murad; Duman, Selcuk; AKBULUT, HABİBAdipose tissue is a source for regenerative medicine applications contains mesenchymal stem cells (MSCs). One of the unique features of MSCs is their trans-differentiation property. Identification of MSCs is accepted by their CD105, CD90 and CD73 markers expression. In lipo aspirate from buttocks and abdominal adipose tissue, these markers were previously shown. In adipose tissue surrounding the vas deferens, we investigated CD105, CD73 and CD90 markers expression. Adipose tissue surrounding the vas deferens was obtained from eight patients who attended to Urology department. Paraffin sections were prepared from adipose tissue after routine histological process. Haematoxylineosin, Toluidine blue and CD105, CD73, CD90 immuno-stainings were performed to the paraffin sections. The strongest expression belonged to CD105, followed by CD90 and finally CD73 which was weakly expressed. Stromal cells derived from the adipose tissue surrounding the vas deferens with similar properties like liposuctioned adipose tissue based on the expression of mesenchymal stem cells markers were reviewed.Publication Metadata only Oxidative stress and phenotype frequencies of paraoxonase-1 in teratozoospermia.(2019-04-22) AKBULUT, H; Ozer, OF; GULER, ERAY METİN; CAGLAR, HİFA GÜLRU; GEVHER, FATİH; KOKTASOGLU, FATMANUR; SELEK, S; ÖZER, ÖMER FARUK; AKBULUT, HABİB; GÜLER, ERAY METİN; ÇAĞLAR, HİFA GÜLRU; GEVHER, FATİH; KÖKTAŞOĞLU, FATMANUR; SELEK, ŞAHABETTİNOxidative stress causes infertility in men by affecting especially sperm morphology. The aim of the study was to examine the frequencies of paraoxonase-1 (PON1) phenotypes and the serum PON1, arylesterase, total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index, catalase and thiol levels in teratozoospermic infertile men and normospermic fertile men. The study included 184 teratozoospermic infertile men and 72 normospermic fertile men. The double substrate method was employed to determine the phenotype distribution of PON1. The evaluation of sperm morphology was made in accordance with the Kruger-s criteria. TAS, catalase and thiol levels were determined to be significantly lower in teratozoospermic infertile men compared to normospermic fertile men. A significant change was not observed in the levels of TOS, PON1 and arylesterase. There was a positive correlation between catalase and thiol levels and sperm morphology. While there were significantly more teratozoospermic men with AA phenotypes compared to normospermic men, there were significantly more persons with AB and BB phenotypes in normospermic men than in teratozoospermic men. As far as we know, such a study was conducted for the first time and suggests that PON1 phenotypic distribution may play a significant role in sterile males because of impaired sperm morphology.Publication Metadata only Ateşli silah yaralanması sonrası rekonstrikte peniste gelişen distal üretral striktürün fibrotik çevre doku ile eksizyonu ( Rekonstrikte penis, parsiyel penektomisi)(2019-10-13T00:00:00Z) GÜRBÜZ, RECAİ; ŞALVARCI, AHMET; KAYALI, YUNUS; AKÇAY, MUZAFFER; AKBULUT, HABİB; DOĞAN, BAYRAM; Gevher, Fatih; İlktaç, Abdullah; KAYALI, YUNUS; AKÇAY, MUZAFFER; AKBULUT, HABİB; DOĞAN, BAYRAMPublication Metadata only Opuntica ficus indica’s anti-cancer and anti-inflammatory effect on prostate cancer cell line(2019-03-14T00:00:00Z) Erdoğdu, Ayşenur; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİM; AKBULUT, HABİB; GÜLER, ERAY METİN; KOÇYİĞİT, ABDÜRRAHİM; AKBULUT, HABİBPublication Metadata only Mesane taşına bağlı penoskrotal lokalizasyonlu fatal nekrotizan fasiitis (Fournier gangreni)(2019-10-13T00:00:00Z) ŞALVARCI, AHMET; GÜRBÜZ, RECAİ; KAYALI, YUNUS; AKÇAY, MUZAFFER; AKBULUT, HABİB; DOĞAN, BAYRAM; Gevher, Fatih; İlktaç, Abdullah; KAYALI, YUNUS; AKÇAY, MUZAFFER; AKBULUT, HABİB; DOĞAN, BAYRAMPublication Metadata only Benign prostat hiperplazisinin cerrahi tedavisi sonrası tanı konulan insidental prostat kanseri(2021-10-01T00:00:00Z) İlktaç, Abdullah; Ersöz, Cevper; Doğan, Bayram; Akçay, Muzaffer; Yıldız, Pelin; Çoban, Ganime; Akbulut, Habib; İLKTAÇ, ABDULLAH; ERSÖZ, CEVPER; DOĞAN, BAYRAM; AKÇAY, MUZAFFER; YILDIZ, PELİN; ÇOBAN, GANİME; AKBULUT, HABİBPublication Metadata only Functional Genetic Variants in Apoptosis-associated FAS and FASL Genes and Risk of Bladder Cancer in a Turkish Population(2014-05-01T00:00:00Z) Verim, Levent; Timirci-Kahraman, Ozlem; AKBULUT, HABİB; AKBAŞ, ALPASLAN; Ozturk, Tulin; Turan, Saime; Yaylim, Ilhan; Ergen, Arzu; Ozturk, Oguz; Isbir, Turgay; AKBULUT, HABİBBackground: The present study aimed to evaluate the role of functional polymorphisms of apoptosis-associated Fatty acid synthase (FAS) and fatty acid synthase ligand (FASL) genes in bladder cancer susceptibility as first presentation in a Turkish population. Patients and Methods: Genotypes of 91 patients with bladder cancer and 101 healthy controls were evaluated for the polymorphism of FAS-1377 G/A and FASL-844 T/C genes by polymerase chain reaction and restriction fragment length polymorphism analysis. Results: The frequency of the FAS-1377 G allele was significantly higher in patients with bladder cancer compared to controls (p<0.001). A significantly increased risk for developing bladder cancer was found for the group bearing a T allele for FASL-844 compared to the homozygous FASL-844 CC genotype (p=0.027). FAS-1377 GG genotype and FASL-844 T allele were found to be independently associated with an increased risk of bladder cancer. Additionally, gene gene interaction analysis revealed that the frequency of FAS-1377AA with FASL-844TC was significantly lower in patients with bladder cancer in comparison to those of controls (p<0.001). Extensive studies for gene gene interaction are still needed. Conclusion: Our study provides new evidence that FAS-1377 G and FASL-844 T alleles may be used as low-penetrant risk factors for bladder cancer development in a Turkish population.