Person: UYSAL, HARUN
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Publication Open Access Use of the gastro-laryngeal tube in endoscopic retrograde cholangiopancreatography cases under sedation/analgesia(2016-05-01) Daskaya, HAYRETTİN; UYSAL, HARUN; Ciftci, Taner; BAYSAL, Birol; IDIN, Kadir; Karaaslan, KAZIM; DAŞKAYA, HAYRETTİN; UYSAL, HARUN; KARAASLAN, KAZıMBackground/Aims: In this study, we aimed to analyze the effects of Gastro-Laryngeal Tube (GLT) use on intraoperative and postoperative hemodynamic parameters, comfort of the procedure, and patients’ satisfaction in endoscopic retrograde cholangiopancreatography (ERCP). Materials and Methods: A total of 80 patients between the ages of 20 and 75 years who were scheduled for elective ERCP were enrolled. The patients were randomly assigned to two groups: groups N and G. Those in group N underwent the procedure with sedation without any airway instruments and those in group G underwent procedure after sedation and airway management with GLT. Intraoperative and postoperative vital signs as well as the satisfaction of the patients were recorded. Results: The duration to esophageal visualization was found to be significantly higher in group N (16 s) than in group G (7 s) (p=0.001). The mean Visual Analogue Scale for Pain (VAS) was significantly higher in group G (1.85) than in group N (0.45) (p=0.016). Group G had higher endoscopist satisfaction scores than group N. The incidence of desaturation during ERCP was significantly higher in group N (60%) than in group G (0%) (p=0.000). Conclusion: In conclusion, ERCP should be performed under optimal conditions to avoid the occurrence of unwanted complications, such as aspiration-related disorders. Therefore, according to the structural properties of GLT, sedation anesthesia application with GLT in ERCP will be safer, more comfortable, and more effective.Publication Metadata only Comparison of LMA® Gastro™ airway and gastrolaryngeal tube in endoscopic retrograde cholangiopancreatography: a prospective randomized observational trial(2021-05-13T00:00:00Z) Uysal, Harun; Senturk, HAKAN; Calim, Muhittin; Daskaya, Hayrettin; Guney, Ibrahim A; Karaaslan, Kazim; UYSAL, HARUN; ŞENTÜRK, HAKAN; DAŞKAYA, HAYRETTİNBackground: New generation airway devices with different designs have been developed as an alternative to endotracheal intubation in order to avoid adverse events associated with sedation in endoscopic procedures and to provide patent airway. We aimed to compare two supraglottic airway devices (SGADs), the LMA® Gastro™ airway and gastrolaryngeal tube (GLT), in terms of airway efficiency, performance during procedure and adverse events in endoscopic retrograde cholangiopancreatography (ERCP). Methods: A hundred-three ERCP patients without high risk of aspiration were included. Patients were randomly allocated to the LMA Gastro and GLT groups. The primary study outcomes were the comparison of the two SGADs in terms of oropharyngeal leak pressure (OLP). Secondary study outcome was SGADs-related adverse events. Results: Procedures were completed with SGADs in fifty patients in each group. The rate of successful insertion at first attempt was 72% in GLT and 96% in LMA Gastro (P=0.004). The mean OLP of LMA Gastro Group (31.8 cmH2O) was significantly higher than that of the GLT Group (26.5 cmH2O), (P=0.0001). However, endoscopists' satisfaction was higher in GLT (P=0.0001). Mucosal damage and sore throat were lower in LMA Gastro Group. Conclusions: LMA® Gastro™ had a higher OLP than GLT. However, GLT was better for endoscopist satisfaction, as it provides more satisfying maneuverability. As to secondary outcome advers events were lower in LMA® Gastro™. The lower complication rates associated with the device and providing a more patent airway also highlighted the apparent clinical efficacy of LMA® Gastro™ than GLT, in ERCP.Publication Metadata only The Effect of Intraoperative Body Temperature on Postoperative Nausea and Vomiting in Pediatric Patients.(2021-08-03T00:00:00Z) Sümer, Ismail; Uysal, HARUN; Yeşiltaş, Serdar; Türkay, Meltem; UYSAL, HARUN; YEŞİLTAŞ, SERDARPublication Metadata only The effect of gender on acute kidney injury developing in the intensive care unit.(2019-07-01T00:00:00Z) Güzel, C; Yeşiltaş, S; Daşkaya, H; Sümer, I; Türkay, M; YEŞİLTAŞ, SERDAR; DAŞKAYA, HAYRETTİN; UYSAL, HARUNPublication Metadata only COMPARISON OF PLETH VARIABILITY INDEX, TRANSESOPHAGEAL ECHOCARDIOGRAPHY, TRANSTHORACIC ECHOCARDIOGRAPHY AND PULMONARY ARTERY CATHETER MEASUREMENTS TO EVALUATE PATIENT VOLUME STATUS(2016-09-01T00:00:00Z) UYSAL, HARUN; KARAASLAN, Kazım; ÇALIM, Muhittin; Nasifov, M.; AYDIN, CEMALETTİN; UYSAL, HARUN; KARAASLAN, KAZıM; ÇALIM, MUHITTIN; AYDIN, CEMALETTİNPublication Open Access Temporary vision loss after spinal anesthesia(2015-01-01) BAŞARANOĞLU, GÖKÇEN; IDIN, KADIR; UMUTOGLU, TARIK; TOPUZ, UFUK; ESEN, ASIM; UYSAL, HARUN; BAŞARANOĞLU, GÖKÇEN; UYSAL, HARUNPerioperative visual loss is a rare complication mostly associated with cardiac, spine, and head and neck surgery that could severely affect quality of life. We report a case of temporary visual loss without any other subjective symptom after spinal anesthesia.Publication Metadata only Comparison of Cytokine Hemadsorption as an Immunomodulator Therapy in COVID-19 Patients with and without Bacterial Sepsis(2022-10-01) Koc S.; Hanikoglu F.; Dokur M.; Polat Y.; Celebi S.; Koc S. G.; Kupeli I.; UYSAL H.; UYSAL, HARUN© 2022 Verlag Klinisches Labor GmbH. All rights reserved.Background: In this retrospective study, we aimed to compare the laboratory and clinical results of cytokine hemadsorption as an immunomodulation therapy in COVID-19 ICU patients with or without sepsis. Methods: The levels of PCT, CRP, and ferritin were determined as indicators of infection/sepsis; the levels of interleukins (IL-6, IL-8 and IL-10, and TNF-α) were determined as indicators of cytokine storm were compared. APACHE score, SOFA score, and mortality rates were compared for the progression of the disease in 23 COVID-19 patients. Results: The therapy was generally successful in reducing the levels of IL-6, IL-8, IL-10, and TNF-α but the levels measured after the procedure did not differ among the patients with or without sepsis, suggesting that the presence of sepsis did not affect the efficacy and function of the cytokine hemadsorption procedure in COVID-19 patients. All parameters were reduced after the procedure except the levels of PCT and ferritin and mortality rates of patients diagnosed with sepsis. The level of PCT was significantly higher in these patients compared with the patients without sepsis while the ferritin and mortality did not show any significant difference between the two groups, suggesting that the cytokine hemadsorption may be safe in the treatment of critical COVID-19 patients. Conclusions: As a result, the progression of sepsis in COVID-19 may be avoided with cytokine hemadsorption applied as an immunomodulator therapy. However, this therapy should be further explored and validated prior to its introduction to everyday clinical practice when the epidemic conditions end.Publication Metadata only The Effect of Sphenopalatine Ganglion Block on the Postoperative Pain in Patients Undergoing Septorhinoplasty.(2020-02-22T00:00:00Z) Ozdem, A; Degirmenci, Nazan; Sen, P; Uysal, H; Turkoz, A; Ozturan, O; DEĞİRMENCİ, NAZAN; ÖZDEM, ABDULLAH; UYSAL, HARUN; ŞEN, PELİN; ŞENTÜRK, EROL; ÖZTURAN, ORHAN; TÜRKÖZ, AYDAObjectives:Publication Metadata only Endoskopik ultrasonografi yapılan olgularda propofole ketamin veya fentanil ilavesinin sedo-analjezi kalitesi üzerine etkileri(2019-09-01T00:00:00Z) Daşkaya, Hayrettin; Uysal, Harun; Yılmaz İnal, Ferda; Esen, Asım; Karaaslan, Kazım; DAŞKAYA, HAYRETTİN; UYSAL, HARUNPublication Open Access Opioid-free total intravenous anesthesia with propofol, dexmedetomidine and lidocaine infusions for laparoscopic cholecystectomy: a prospective, randomized, double-blinded study(2015-05-01) BAKAN, Mefkur; UMUTOGLU, Tarik; TOPUZ, Ufuk; UYSAL, HARUN; Bayram, MEHMET; Kadioglu, HÜSEYİN; SALIHOGLU, Ziya; UYSAL, HARUN; BAYRAM, MEHMET; KADIOĞLU, HÜSEYİNJustificativa e objetivos: O uso de opioides no período intraoperatório pode estar associado à hiperalgesia e ao aumento do consumo de analgésicos no período pós-operatório. Efeitos colaterais como náusea e vômito no período pós-operatório, por causa do uso perioperatório de opioides, podem prolongar a alta. Nossa hipótese foi que a anestesia venosa total com o uso de lidocaína e dexmedetomidina em substituic¸ão a opioides pode ser uma técnica opcional para a colecistectomia laparoscópica e estaria associada a uma menor solicitac¸ão de fentanil e incidência de náusea e vômito no período pós-operatório. Métodos: Foram programados para colecistectomia laparoscópica eletiva 80 pacientes adultos, estado físico ASA I-II. Os pacientes foram randomicamente alocados em dois grupos para receber anestesia livre de opioides com infusões intravenosas (IV) de dexmedetomidina, lidocaína e propofol (Grupo DL) ou anestesia baseada em opioides com infusões de remifentanil e propofol (Grupo RF). Todos os pacientes receberam um regime padrão de analgesia multimodal. Um dispositivo de analgesia controlada pelo paciente foi ajustado para liberar fentanil IV por seis horas após a cirurgia. O desfecho primário foi o consumo de fentanil no pós-operatório. Resultados: O consumo de fentanil na segunda hora de pós-operatório foi significativamente menor no grupo DL do que no Grupo RF, 75 ± 59g e 120 ± 94g, respectivamente, mas foi comparável na sexta hora de pós-operatório. Durante a anestesia, houve mais eventos hipotensivos no Grupo RF e mais eventos hipertensivos no grupo DL, ambos estatisticamente significativos. Apesar de apresentar um tempo de recuperac¸ão mais prolongado, o Grupo DL apresentou escores de dor e consumo de analgésicos de resgate e de ondansetrona significativamente mais baixos