Person: ONSUN, NAHIDE
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Publication Metadata only A'dan Z'ye Kaposi Sarkomu(Galenos Yayın Evi, 2023-03-01) Onsun N. (Editör); ONSUN, NAHIDEPublication Metadata only Dermoscopic Evolution of Pediatric Nevi(2019-10-01T00:00:00Z) CENGİZ, Fatma Pelin; Yilmaz, Yaren; EMİROĞLU, Nazan; ONSUN, NAHİDE; CENGİZ, FATMA PELIN; EMİROĞLU, NAZAN; ONSUN, NAHIDEBackground: The incidence of pediatric melanoma is very rare. Dermoscopic features help to distinguish pediatric melanoma and common nevi. Objective: To study the evolution of dermoscopic findings in benign nevi in childhood through serial observation and photography. Methods: We examined 504 melanocytic lesions in 100 patients. From each participant, dermoscopic images of the nevi from 4-year dermoscopic follow-up were obtained, including randomly selected nevi. Results: The most common dermoscopic patterns were homogeneous (193 nevi; 38.3%), globular (92 nevi; 18.3%), and reticular (86 nevi; 17.1%). Dermoscopic pattern changes were detected in 27% of patients aged 2 similar to 10 years and in 20% of patients aged 11 similar to 16 years. The main pattern changes consisted of the transition from homogeneous to globular-homogeneous (16%), from homogeneous to reticular-homogeneous (12%) and from globular to globular-homogeneous (10%). Although 257 of the 504 nevi (51.0%) have stable duration without size changes, 169 of the 504 nevi (33.5%) were enlarged, and 78 of the 504 nevi (15.5%) had become smaller. Conclusion: These results contrast with the prevailing view that dermoscopic patterns in pediatric nevi are usually characterized by globular patterns and that melanocytic nevi generally undergo a characteristic transition from a globular pattern to a reticular pattern. Fifty one percent of patients did not exhibit a size change. While 33% of patients had symmetrical enlargement, 15% of patients had involution. Therefore, enlargement is a common dermoscopic change in pediatric nevi, and is not a specific sign of pediatric melanoma.Publication Metadata only Cyclosporine(2022-01-01T00:00:00Z) ONSUN, Nahide; ONSUN, NAHIDECyclosporine is an immunosuppressive agent used in the treatment of psoriasis. It shows its action through calcineurin inhibition and T-lymphocytes. With its rapid effect, it can be used as an induction therapy in plaque, pustular and erythrodermic psoriasis. Its most common side effects are elevated serum creatinin values and arterial hypertension. In long-term treatment not to exceed 2 years, it may be used under nephrology control.Publication Metadata only Prevalence and determinants of sunbed use in thirty European countries: data from the Euromelanoma skin cancer prevention campaign.(2019-03-01T00:00:00Z) Suppa, M; Gandini, S; Njimi, H; Bulliard, JL; Correia, O; Duarte, AF; Peris, K; Stratigos, AJ; Nagore, E; Longo, MI; Bylaite-Bucinskiene, M; Karls, R; Helppikangas, H; Euromelanoma, Working; Del, Marmol; ONSUN, NAHIDEPublication Metadata only Primary cutaneous lymphomas and Coronavirus disease-2019: A critical overview of primary cutaneous lymphoma management in pandemic(2022-01-01T00:00:00Z) Ornek, Sinem; BİLGİÇ, ASLI; YAZİCİ, SERKAN; BAYRAMGÜRLER, DİLEK; ŞANLI, HATİCE; ONSUN, Nahide; ONSUN, NAHIDECoronavirus disease-2019 (COVID-19) is a serious cause of respiratory tract infection, and its severe course has been associated with some risk factors, including malignancies and immunosuppressive treatments. Primary cutaneous lymphomas (PCL) are a heterogeneous group of immune system neoplasms, which are subclassified as indolent and aggressive types according to their survival rates. PCL treatment ranges from skin-based therapies to systemic treatments, of which immunosuppressive effects occur in some. During the COVID-19 pandemic, patients with PCL should be protected from possible COVID-19 complications, and the optimal treatment should be provided to control the disease taking into account the treatment-related risks. Therefore, recommendations about the management of patients with PCL during the COVID-19 pandemic were overviewed in light of the literature. Topical treatments can generally be considered low-risk therapies and can be continued without interruption. Phototherapy, skin radiotherapy, and total skin electron beam therapy increase the risk of COVID-19 exposure due to hospital visits. Moderate-risk therapies like interferons, systemic retinoids, methotrexate, and systemic corticosteroids might be used with caution. Advanced-stage patients with COVID-19 related comorbidity and who previously received immunosuppressive therapy should be carefully evaluated. Biological agents and systemic chemotherapeutics, which are considered high-risk, should not be delayed when needed. However, increasing intervals between treatments or switching to alternative therapies may be preferable in stable diseases. Most importantly, all patients with PCL should be ensured to comply with general protection measures as long as the pandemic continues.Publication Metadata only Electrocardiographic P-wave characteristics in patients with psoriasis vulgaris(2013-03-01) Bacaksiz, AHMET; ERDOGAN, Ercan; TASAL, Abdurrrahman; VATANKULU, Mehmet Akif; KUL, Seref; SEVGILI, Emrah; ERTAS, Gokhan; DIZMAN, DİDEM; Onsun, NAHİDE; Uysal, Omer; BACAKSIZ, AHMET; DİZMAN, DİDEM; ONSUN, NAHIDE; UYSAL, ÖMERPurpose. Psoriasis vulgaris is one of the most common skin disorders. Patients with psoriasis carry an excessive risk of atrial fibrillation (AF). The differences between the maximum (Pmax) and the minimum (Pmin) P-wave duration on ECG are defined as P-wave dispersion (PWD). Prolongation of PWD is an independent risk factor for the development of AF. The aim of this the study was to investigate P-wave duration and PWD in patients with psoriasis. Methods. Sixty-one adult patients with psoriasis vulgaris (group 1) and 58 age and sex-matched healthy individuals (group 2) were included in this study. ECG recordings were obtained, and the P-wave variables were calculated. Results were reported as mean ± standard deviation and percentages. Continuous variables were analysed using Student’s t test. A value of P < 0.05 was considered statistically significant. Results. Pmax and PWD were significantly higher in group 1 than in group 2 (108.8 ± 21.3 ms versus 93.3 ± 13.0 ms, P < 0.001; 67.4 ± 22.9 ms versus 45.0 ± 19.6 ms, P < 0.001, respectively). Also, Pmin was significantly lower in group 1 (41.3 ± 12.3 ms versus 48.3 ± 14.3 ms, P = 0.04). The psoriasis disease activity score and hsCRP correlated with PWD (P < 0.01). Conclusions. Atrial conduction of sinus impulses was impaired in patients with psoriasis vulgaris. It was more prominent in patients with severe disease. Physicians caring for patients with psoriasis vulgaris should screen them for AF development.Publication Metadata only Association of sunbed use with skin cancer risk factors in Europe: an investigation within the Euromelanoma skin cancer prevention campaign.(2019-03-01T00:00:00Z) Suppa, M; Gandini, S; Njimi, H; Bulliard, JL; Correia, O; Duarte, AF; Peris, K; Stratigos, AJ; Nagore, E; Longo, MI; Bylaite-Bucinskiene, M; Karls, R; Helppikangas, H; Euromelanoma, Working; Del, Marmol; ONSUN, NAHIDE