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Publication Open Access Which dermatology patients attend to Dermatology Outpatient Clinics during the SARS-CoV-2 outbreak in Turkey and what happened to them?(2020-05-11T04:00:00Z) CENGİZ, Fatma Pelin; EMİROĞLU, Nazan; BAHALI, ANIL GÜLSEL; DİZMAN, DİDEM; TAŞLIDERE, NAZAN; MERT, Ömer; Akarslan, Tahsin Cagdas; Gunes, Begum; KÜÇÜK, Özlem Su; ONSUN, Nahide; CENGİZ, FATMA PELIN; EMİROĞLU, NAZAN; BAHALI, ANIL GÜLSEL; DİZMAN, DİDEM; TAŞLIDERE, NAZAN; GÜNEŞ, BEGÜM; MERT, ÖMER; SU KÜÇÜK, ÖZLEM; ONSUN, NAHIDECoronavirus disease, first emerged in Wuhan, rapidly spread all over the world since December 2019. There are concerns about elective dermatology appointments and its results. Herein, we aimed to find out which type of dermatologic patients attended to dermatology outpatient clinic. The patients visiting the clinics for elective dermatologic diseases between March 11 and 18, 2020, were included in this study. Their age, sex, diagnosis of disease, requirement for emergent intervention, and their medical records about COVID-19 were obtained. There were 390 patients attending to the dermatology outpatient clinic in this period. The most common disease was acne (N: 94, 24%), only 19% of patients need emergent interventions or dose adjustment. There were 40 (10%) patients over the age of 65. After their visits, five patients were diagnosed as COVID-19 in 2weeks. Dermatologic examinations may be a vector for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission since being closed to the patient. Five of our patients were diagnosed as COVID-19 after their elective visit to hospital. Since the asymptomatic course of some young patients, most of our patients were not screened for COVID-19. Our findings support the concerns of elective physician examinations.Publication Open Access A generalized pustular psoriasis flare after CoronaVac COVID-19 vaccination: Case report(2021-01-01T00:00:00Z) ONSUN, Nahide; KAYA, GÖKHAN; IŞIK, BENGİSU GÜÇKAN; GÜNEŞ, BEGÜM; ONSUN, NAHIDE; KAYA, GÖKHAN; IŞIK, BENGİSU GÜÇKAN; GÜNEŞ, BEGÜMCoronoVac is a non-viable vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Nowadays, there has been vaccination program for at-risk groups and older adults in Turkey. We here present 72-year-old male psoriasis patient who developed generalized pustular psoriasis flare after administration of CoronoVac. The COVID-PCR test was negative and investigations for flare etiology were all normal. He was first (to the best of our knowledge) psoriasis patient who developed an erythrodermic flare after the first dose of CoronaVac vaccine.Publication Open Access Retention and survival rate of etanercept in psoriasis over 15 years and patient outcomes during the COVID-19 pandemic: The real-world experience of a single center(2020-12-01T00:00:00Z) GÜNEŞ, BEGÜM; ONSUN, Nahide; YABACI, AYŞEGÜL; ONSUN, NAHIDE; GÜNEŞ, BEGÜM; YABACI TAK, AYŞEGÜLThere have been a number of investigations of the efficacy and safety of etanercept. This study was performed to obtain long-term drug survival data (ie, time to drug discontinuation) for etanercept, and the reasons for its discontinuation. The study population consisted of patients with psoriatic arthritis and psoriasis followed up by our clinic, registered in the Turkish Psoriasis Registry (PSR-TR) and treated with etanercept for at least 4 weeks between January 1, 2005, and January 31, 2020. The efficacy of etanercept was evaluated in terms of the Psoriasis Area and Severity Index (PASI) 75, PASI 90 and PASI 100 response rates at 12, 24, 36, and 48 weeks, and annually thereafter. The behaviors of the patients with respect to the use of etanercept, and the outcomes of those who continued to use it during the COVID-19 pandemic, were also investigated.Publication Open Access Prognostic factors of patients with mycosis fungoides(2020-01-01T00:00:00Z) BAHALI, ANIL GÜLSEL; Su, Özlem Su; CENGİZ, Fatma Pelin; EMİROĞLU, Nazan; Ozkaya, Dilek Biyik; ONSUN, Nahide; BAHALI, ANIL GÜLSEL; SU KÜÇÜK, ÖZLEM; CENGİZ, FATMA PELIN; EMİROĞLU, NAZAN; ONSUN, NAHIDEIntroduction: Mycosis fungoides (MF) is the most common type of primary cutaneous T-cell lymphoma. Prognostic factors may help to evaluate the course of the disease and may also be useful in selecting appropriate treatment plans for patients.Publication Open Access Clinical and histopathological improvement of scleromyxedema-induced microstomia after hyaluronidase injection(2022-05-01T00:00:00Z) AKASLAN, TAHSİN ÇAĞDAŞ; YILDIZ, PELİN; ONSUN, Nahide; AKASLAN, TAHSİN ÇAĞDAŞ; YILDIZ, PELİN; ONSUN, NAHIDEIntroduction Scleromyxedema is a rare primary cutaneous mucinosis characterized by numerous firm, waxy, confluent papules. Recently, intravenous immunoglobulin (IVIG) is accepted by many authors as the first-line treatment option for severe cases. We report a 69-year-old male patient who has been suffering from scleromyxedema, with reduced mouth opening. He has been on a high-dose IVIG regime for 5 years. Methods The patient stated that he had difficulty in wearing and removing his dentures because of reduced mouth opening lately. Before considering to add any other immunosuppressants to his regime, we injected 1500 IU of hyaluronidase in total in one session periorally. The patient has been told open his mouth maximum and photographs have been taken before injections and after one month. We used a photo measurement application when evaluating microstomia to increase accuracy. We also took punch biopsies in order to evaluate effect of hyaluronidase histopathologically before and one month after injections. Results One month later, he was able to reattach and remove his dentures without adding any adjuvant immunosuppressants other than hyaluronidase. Mouth opening was increased in measurements and histopathologically, mucin deposition, fibroblastic proliferation, and perivascular lymphocytic infiltration were decreased. Conclusions We think hyaluronidase is a safe, easily accessible, and effective treatment option for microstomia caused by scleromyxedema.