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AYDIN, SİNEM

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    PublicationOpen Access
    The effectiveness of Power Doppler vocal fremitus imaging in the diagnosis of breast hamartoma
    (2014-09-01) Yildiz, Seyma; BAKAN, Ayse Ahsen; Aydin, SİNEM; Kadioglu, HÜSEYİN; SERTER, Asli; Bilgin, Sennur; Alkan, ALPAY; YILDIZ, ŞEYMA; AYDIN, SİNEM; KADIOĞLU, HÜSEYİN; ALKAN, ALPAY
    Objectives: To evaluate the usefulness of power Doppler vocal fremitus (PDVF) breast sonography for differentiation of hamartomas from other breast (malign or benign) masses. Material and methods: Two hundred and six breast masses in 180 women were evaluated. The breast lesions were scanned first by mammography (MG), then by ultrasonography (US) with PDVF imaging. Finally, biopsy was performed on lesions suspicious for malignancy (n=172). We used PDVF imaging to evaluate whether the Power acoustic Doppler artifact existed in all breast lesions. Results: Pathology results of 172 biopsied lesions showed that 83 were malign and 89 masses were benign. Totally 39 breast hamartomas were diagnosed radiologically (n=25) or histopathologically (n=14). All hamartomas (n=39) produced the power acoustic Doppler artifact as the surrounding tissue at the same depth in PDVF imaging. On the other hand, none of the malign or benign lesions, apart from hamartomas, evidenced a similar vibrational artifact as the surrounding tissue at the same depth in the PDVF imaging. Conclusion: PDVF imaging during breast sonography is an invaluable technique in the identification of breast hamartomas from other benign or malign breast masses.
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    PublicationOpen Access
    The association of breast arterial calcification and metabolic syndrome
    (2014-01-01) Yildiz, Seyma; Toprak, HÜSEYİN; Aydin, SİNEM; Bilgin, MEHMET; Oktay, Veysel; Abaci, Okay; Kocas, Cuneyt; YILDIZ, ŞEYMA; TOPRAK, HÜSEYİN; AYDIN, SİNEM; BİLGİN, MEHMET
    OBJECTIVES: We investigated the relationship between metabolic syndrome and breast arterial calcification detected via mammography in a cohort of postmenopausal subjects. METHODS: Among 837 patients referred to our radiology department for mammographic screening, 310 postmenopausal females (105 patients with and 205 patients without breast arterial calcification) aged 40 to 73 (mean 55.9¡8.4) years were included in this study. The groups were compared with respect to clinical characteristics and metabolic syndrome criteria. Univariate and multivariate analyses identified the factors related to breast arterial calcification. RESULTS: Age, postmenopausal duration and the frequencies of diabetes mellitus, hypertension and metabolic syndrome were significantly higher in the subjects with breast arterial calcification than in those without (p,0.05). Multivariate analysis indicated that age (OR = 1.3, 95% CI = 1.1–1.6, p = 0.001) and metabolic syndrome (OR = 4.0, 95% CI = 1.5210.4, p = 0.005) were independent predictors of breast arterial calcification detected via mammography. The independent predictors among the features of metabolic syndrome were low levels of high-density lipoproteins (OR = 8.1, 95% CI = 1.0264.0, p = 0.047) and high blood pressure (OR = 8.7, 95% CI = 1.5249.7, p = 0.014). CONCLUSIONS: The likelihood of mammographic detection of breast arterial calcification increases with age and in the presence of hypertension or metabolic syndrome. For patients undergoing screening mammography who present with breast arterial calcification, the possibility of metabolic syndrome should be considered. These patients should be informed of their cardiovascular risk factors and counseled on appropriate lifestyle changes.