Person: YURTSEVER, İSMAİL
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Publication Metadata only Relationship between KRAS mutation and diffusion weighted imaging in colorectal liver metastases; Preliminary study.(2020-02-25T00:00:00Z) Türk, HM; Gültekin, MEHMET ALİ; Uysal, Ö; Beşiroğlu, M; Yilmaz, TF; Yurtsever, I; GÜLTEKİN, MEHMET ALİ; TÜRK, HACI MEHMET; TOPRAK, HÜSEYİN; YURTSEVER, İSMAİL; YILMAZ, TEMEL FATİH; SHARIFOV, RASUL; UYSAL, ÖMERPurpose: We aimed to investigate whether there are any differences in apparent diffusion coefficient (ADC) values obtained from colorectal liver metastases (CRLM) according to Kirsten rat sarcoma (KRAS) gene mutation status.Publication Metadata only Radiosurgery, Gamma Knife Radiosurgery, Vestibular schwannomas, tumor volume, Diffusion Tensor Imaging, Apparent diffusion coefficient.(2021-11-01T00:00:00Z) Kaya, Ahmet; Çeşme, Dilek Hacer; Yurtsever, İsmail; Sarı, Lütfullah; Alkan, Gökberk; Seyithanoglu, Mehmet Hakan; KAYA, AHMET; YURTSEVER, İSMAİLPublication Metadata only Development of Antiarrhythmic Therapy-Resistant Ventricular Tachycardia, Ventricular Fibrillation, and Premature Ventricular Contractions in a 15-Year-Old Patient(2020-09-01T00:00:00Z) Yozgat, Can Yilmaz; YEŞİLBAŞ, Osman; İŞCAN, AKIN; YURTSEVER, İsmail; OTÇU TEMUR, Hafize; BAYRAMOVA, NİGAR; ERGÜN, GÖKÇE; TEKİN, NUR; YOZGAT, Yılmaz; YEŞİLBAŞ, OSMAN; İŞCAN, AKIN; YURTSEVER, İSMAİL; OTÇU TEMUR, HAFİZE; BAYRAMOVA, NİGAR; ERGÜN, GÖKÇE; TEKİN, NUR; YOZGAT, YILMAZSudden cardiac arrest (SCA) is the sudden cessation of regular cardiac activity so that the victim becomes unresponsive, with no signs of circulation and no normal breathing. Asystole, ventricular tachycardia (VT), ventricular fibrillation (VF), and pulseless electrical activity are the underlying rhythm disturbances in the pediatric age group. If appropriate interventions (cardiopulmonary resuscitation-CPR and/or defibrillation or cardioversion) are not performed rapidly, this condition progresses to sudden death. There have not been many reported cases of the approach and treatment of cardiac arrhythmias after SCA. Herein, we would like to report a case of a 15-year-old female patient with dilated cardiomyopathy (DCM) who was admitted to our clinic a year ago, and while her left ventricular systolic functions were improved, SCA suddenly occurred. Since the SCA event occurred in another city, intravenous treatment of amiodarone was done immediately and was switch to continuous infusion dose of amiodarone until the patient arrived at our institution-s pediatric intensive care unit (PICU) 3hours later. During the patient-s 20-day PICU hospitalization, she developed pulseless VT and VF from time to time. The patient-s pulseless VT and VF attacks were brought under control by the use of a defibrillator and added antiarrhythmic drugs (amiodarone, flecainide, esmolol, and propafenone). Intriguingly, therapy-resistance bigeminy with premature ventricular contractions (PVCs) continued despite all these treatments. The patient did not have adequate blood pressure measured by invasive arterial blood pressure monitoring while having bigeminy PVCs. The intermittent bigeminy PVCs ameliorated rapidly after intermittent boluses of lidocaine. In the end, multiple antiarrhythmic therapies and intermittent bolus lidocaine doses were enough to bring her cardiac arrhythmias after SCA under control. This case illustrates that malign PVC-s should be taken very seriously, since they may predispose to the development of VT or VF. Also, this case highlights the importance of close vigilance of arterial pressure tracings of patients with bigeminy PVCs which develop after SCA and should not be accepted as normal.Publication Metadata only CA 19-9 Eksprese Etmeyen Pankreaatik Duktal adenokarsinom Tanılı Hastaların Demografik Özellikleri(2021-11-21T00:00:00Z) Köker, İbrahim Hakkı; Yurtsever, İsmail; Şentürk, Hakan; KÖKER, İBRAHİM HAKKI; YURTSEVER, İSMAİL; ŞENTÜRK, HAKANPublication Metadata only The Utility and Efficiency of Diffusion Tensor Imaging Values to Determine Epidermal Growth Factor Receptor Gene Mutation Status in Brain Metastasis from Lung Adenocarcinoma; A Preliminary Study(2021-02-01T00:00:00Z) Gültekin, Mehmet Ali; Alkan, Alpay; Yılmaz, Temel Fatih; Yurtsever, İsmail; Atasoy, Bahar; Aliyev, Altay; GÜLTEKİN, MEHMET ALİ; TÜRK, HACI MEHMET; YURTSEVER, İSMAİL; YILMAZ, TEMEL FATİH; ALKAN, ALPAYPublication Metadata only Prediction of mortality at first admission in COVID-19 pneumonia: A retrospective cohort study(2022-01-01T00:00:00Z) Koker, Ibrahi; Yurtsever, İsmail; Uysal, Omer; Huseynov, Nurlan; Senturk, Hakan; YURTSEVER, İSMAİLPublication Metadata only A case report of fulminant hepatitis due to ribociclib with confirmed by liver biopsy in breast cancer(2021-06-01T00:00:00Z) TOPÇU, Atakan; YASİN, Ayşe İrem; SHBAIR, ABDALLAH T.M.; BEŞİROĞLU, MEHMET; ŞİMŞEK, MELİH; SUCUOĞLU İŞLEYEN, ZEHRA; YURTSEVER, İSMAİL; GÜCİN, ZÜHAL; ŞEKER, Mesut; TÜRK, HACI MEHMET; TOPÇU, ATAKAN; YASİN, AYŞE İREM; SHBAIR, ABDALLAH T.M.; BEŞİROĞLU, MEHMET; ŞİMŞEK, MELİH; SUCUOĞLU İŞLEYEN, ZEHRA; YURTSEVER, İSMAİL; GÜCİN, ZÜHAL; ŞEKER, MESUT; TÜRK, HACI MEHMETIntroduction Breast cancer is the most frequently diagnosed cancer in women worldwide. Ribociclib is now frequently used in the treatment of metastatic hormone-positive and human epidermal growth factor receptor 2 (HER 2)-negative breast cancer. Case Report A 54-year-old woman with breast cancer presented at a clinic in November 2017 with multiple lung and bone metastases. After receiving multiple lines of treatment due to disease progression, ribociclib and fulvestrant were initiated. Grade 4 toxicity was observed due to ribociclib during follow-up, and ribociclib was discontinued permanently. Management & Outcome: Given that liver transaminases and bilirubin elevation persisted despite discontinuation of the treatment, other reasons for liver toxicity were investigated. Abdominal MRI showed no liver metastases, although there was acute hepatitis. A liver biopsy was performed to determine the etiology. The pathology result was compatible with drug-induced acute fulminant toxic hepatitis. After liver biopsy, prednisolone treatment was initiated, after which the laboratory findings normalized. Discussion Although there are reported cases showing improvement in liver enzymes after ribociclib discontinuation, in our case, no recovery from hepatotoxicity was noticed. The treatment was changed to another hormonal pathway therapy option, exemestane. To the best of our knowledge, this is the first case in the literature reporting this rare side effect of ribociclib, which is a liver biopsy-proven fulminant hepatitis.Publication Metadata only Relationship with programmed cell death ligand 1 (PD-L1) and DTI features in brain metastases of non-small cell lung cancer; Preliminary study.(2021-02-17T00:00:00Z) Yurtsever, İsmail; Yilmaz, Temel Fatih; Turk, Hacı Mehmet; Gultekin, Mehmet Ali; Besiroglu, Mehmet; Cesme, DİLEK HACER; Shbair, Abdallah T M; Alkan, ALPAY; YILMAZ, TEMEL FATİH; YURTSEVER, İSMAİL; TÜRK, HACI MEHMET; GÜLTEKİN, MEHMET ALİ; ÇEŞME, DİLEK HACER; ALKAN, ALPAYPublication Metadata only The Effectiveness of Diffusion Tensor Imaging in Determining Radiological Response after Radiosurgery in Patients with Vestibular Schwannoma.(2021-01-27T00:00:00Z) Cesme, DİLEK HACER; Alkan, Alpay; Sari, Lutfullah; Kaya, Ahmet; Yurtsever, Ismail; Alkan, Gokberk; Seyithanoglu, Mehmet Hakan; ÇEŞME, DİLEK HACER; ALKAN, ALPAY; YURTSEVER, İSMAİL; SEYİTHANOĞLU, MEHMET HAKAN; HATİBOĞLU, MUSTAFA AZİZPublication Metadata only Oxidative Stress Level in Patients with Subarachnoid Hemorrhage.(2021-12-12T00:00:00Z) Abdallah, Anas; Guler, Eray Metin; Çınar, İrfan; Papaker, Meliha Gündağ; Dündar, Tolga Turan; Yurtsever, İSMAİL; GUNDAG, MELİHA; ÖZER, ÖMER FARUK; YURTSEVER, İSMAİL; DÜNDAR, TOLGA TURAN