Person:
GÖREN, AHMET CEYHAN

Profile Picture
Google ScholarScopusORCIDPublons
Status
Kurumdan Ayrılmıştır
Organizational Units
OrgUnit Logo
Organizational Unit
Job Title
First Name
AHMET CEYHAN
Last Name
GÖREN
Name
Email Address
Birth Date

Filters

20205
Reset filters

Settings

Start date: 2020 × End date: 2022 × Author: Carikci, Sema ×

Search Results

Now showing 1 - 5 of 5
  • Thumbnail Image
    PublicationOpen Access
    The phenolic contents, antioxidant and anticholinesterase activity of section Amaracus (Gled.) Vogel and Anatolicon Ietsw. of Origanum L. species
    (2020-04-01T00:00:00Z) Ozer, Zuleyha; GÖREN, AHMET CEYHAN; Kilic, Turgut; Oncu, Merve; Carikci, Sema; Dirmenci, Tuncay; GÖREN, AHMET CEYHAN
    Origanum boissieri Ietsw., O. saccatum P.H.Davis, O. solymicum P.H.Davis and O. ayliniae Dirmenci & T.Yazici belonging to sect. Amaracus (Gled.) Vogel, O. sipyleum L. and O. hypericifolium O.Schwarz & P.H.Davis belonging to sect. Anatolicon Ietsw. were analyzed for their chemical composition of essential oil and phenolic components. The essential oil compositions were analysed by using GC-MS and GC-FID. The phenolic contents of the chloroform, acetone, and methanol extracts were analyzed using LC-MS/MS. Antioxidant activities of the extracts were investigated by using three methods; DPPH free radical scavenging activity, beta-carotene linoleic acid assays and CUPRAC assays. The essential oil compositions of the section Amaracus were found to be as carvacrol type (O. ayliniae, O. boissieri) and p-cymene type (O. saccatum, O. solymicum). In the section of Anatolicon, while O. sipyleum was found as gamma-terpinene type, O. hypericifolium was carvacrol type. In the extracts, the most abundant components were determined as flavonoids, coumaric acids and derivatives. Especially rosmarinic acid and penduletin were detected in high amounts. Among the studied species, extracts of O. ayliniae showed quite good activity for all methods. The extracts from all species showed remarkable antioxidant activity. Inhibition capability of the extracts against acetyl and butyrylcholinesterase enzymes (AChE and BChE) were determined. The extracts were found as inactive against AChE. The moderate inhibition capacity observed against BChE. (C) 2020 The Authors. Published by Elsevier B.V. on behalf of King Saud University.
  • No Thumbnail Available
    PublicationMetadata only
    Diterpenoid and phenolic contents of Sideritis hololeuca Boiss & Heldr. Apud Bentham with antioxidant and anticholinesterase activity
    (2020-05-01T00:00:00Z) Carikci, Sema; GÖREN, AHMET CEYHAN; Kilic, Turgut; GÖREN, AHMET CEYHAN
  • No Thumbnail Available
    PublicationMetadata only
    Determination of secondary metabolites of Origanum vulgare subsp. hirtum and O. vulgare subsp. vulgare by LC-MS/MS
    (2020-01-01T00:00:00Z) Ozer, Zuleyha; Carikci, Sema; Yilmaz, Hasibe; Kilic, Turgut; Dirmenci, Tuncay; GÖREN, AHMET CEYHAN; GÖREN, AHMET CEYHAN
    Secondary metabolites of solvent extracts of Origanum vulgare subsp. hirtum and O. vulgare subsp. vulgare were determined using liquid chromatography-mass spectrometry (LC-MS/MS). Curcumin was used as an internal standard. Rosmarinic acid was determined as the main compound of studied extracts together with other phenolic acid derivatives. In LC-MS/MS analyses, relative standard deviations (RSD %) ranged between 0.11-9.47. The correlation values were found to be greater than 0.97 for each investigated analyte.
  • No Thumbnail Available
    PublicationMetadata only
    Composition of the essential oil of Satureja metastasiantha: a new species for the flora of Turkey
    (2020-01-01T00:00:00Z) Carikci, Sema; GÖREN, AHMET CEYHAN; Dirmenci, Tuncay; Yalcinkaya, Burhanettin; Erkucuk, Aysen; TOPÇU, GÜLAÇTI; GÖREN, AHMET CEYHAN; TOPÇU, GÜLAÇTI
    The aerial parts of Satureja metastasiantha were hydrodistilled for 3 h using a Clevenger-type apparatus. The essential oils were analyzed by gas chromatography/flame ionization detector and gas chromatography/mass spectrometry, simultaneously, the main compounds of which were characterized as p-cymene (22.3%), thymol (21.0%), carvacrol (18.45%), and gamma-terpinene (12.1%). Antioxidant capacity, acetylcholinesterase and butyryl-cholinesterase inhibition effects, and antimicrobial and antifungal properties of the species were evaluated. The anticholinesterase activity of the essential oil of S. metastasiantha was observed with 30% inhibition at 200 mu g/mL. The essential oil of the species showed activity against Staphylococcus aureus with 128 mu g/mL minimum inhibitory concentration value.
  • No Thumbnail Available
    PublicationMetadata only
    Phytochemical Screening, Antioxidant and Anticholinesterase Activity of Origanum amanum Post Endemic to Turkey
    (2020-01-01T00:00:00Z) Carikci, Sema; GÖREN, AHMET CEYHAN; Kilic, Turgut; Dirmenci, Tuncay; GÖREN, AHMET CEYHAN
    The phenolic and essential oil profiles and, antioxidant and anticholinesterase activities (AChE and BChE inhibitory activities) of Origanum amanum Post endemic to Turkey were investigated. The oil was obtained by applying hydrodistillation method and analyzed by GC-MS/MS. The plant was extracted with chloroform (C), acetone (Ac) and methanol (M). The extracts were analyzed through LC-MS/MS and the phenolic compounds were determined in quantitative amounts. Inhibition of lipid peroxidation, Cu2+ and DPPH scavenging and anticholinesterase activity of the extracts were analyzed. The main compounds of the essential oil of O. amanum were determined as cymene, carvacrol and gamma-terpinene. Rosmarinic, t-ferulic and caffeic acids were determined as the main compounds of the extracts. While the extracts did not inhibit AChE, Ac extract inhibited BChE moderately. Moreover, acetone and methanol extracts of O. amanum showed good antioxidant activity.