Altintas, OzgeAntar, VeyselBaran, OguzKaratas, ErsinAltintas, Mehmet OzgenKesgin, SidikaBuyukpinarbasili, NurKOÇYİĞİT, ABDÜRRAHİMAsil, Talip2020-09-092020-09-092019-12-01Altintas O., Antar V., Baran O., Karatas E., Altintas M. O. , Kesgin S., Buyukpinarbasili N., KOÇYİĞİT A., Asil T., -Neuroprotective effects of hemicraniectomy in malignant middle cerebral artery infarctions: experimental study-, JOURNAL OF NEUROSURGICAL SCIENCES, cilt.63, ss.714-722, 2019http://hdl.handle.net/20.500.12645/18604BACKGROUND: Despite optimal medical therapy the mortality rate approaches 50% in MCA infarctions. Although recent studies have been showed life-saving effect of hemicraniectomy; there are a few data available in regard to neuroprotection effect of decompressive craniectomy (DC). We induced a malignant cerebral ischemia model by intraluminal permanent middle cerebral artery occlusion (MCAo) in male rats for defining the neuroprotective effects of early DC on brain-blood barrier (BBB) molecular changes, infarct size and cerebral edema.enArticleWOS:0005084676000128507797220710.23736/s0390-5616.16.03444-526439453