UMURHAN AKKAN, Jülide CananHAMZAYEV, Igbal2020-08-142020-08-142018http://hdl.handle.net/20.500.12645/18362Thesis (Medical)--Bezmialem Vakıf University, Faculty of Medicine, Department of Eye Diseases, Istanbul, 2018Purpose : To evaluate the performance and safety of an ab interno gel stent, a minimally invasive glaucoma surgery device, in open angle glaucoma Materials and Methods : Medical records of 18 eyes of 15 patients undergone gel implantation with the same surgeon and same technique between June 2016 and April 2017 in the glaucoma unit of our clinic were evaluated retrospectively. Complete success was defined as intraocular pressure (IOP) reduction ≥20% from preoperative baseline without any glaucoma medications while partial success as IOP reduction of ≥20% with medications. Failure was defined as vision loss of light perception or worse, need for additional glaucoma surgery, or <20% reduction of IOP from baseline. Results : Mean intraocular pressure dropped from 20.4±4.1 (15-30) mmHg pre-op to 11±4.1(5-18), 12.6±3.9 (7-20), 13.3±2.7 (8-18), 13.5±3.1 (8-19), and 14.2±3.2 (8-21), 14.2±2.3 (11-17) mmHg at 1 week, 1, 3, 6, and 12 months (p < 0.001, Wilcoxon signed ranks) consecutively. Mean number of medications dropped from 2.2±0.7 preoperatively to 0.5±0.6 (p <0.001) at 1-year follow-up. 46.6% of eyes achieved complete success and 86.6% qualified success. Complications included hyphema in 2 eyes, and implant extrusion in 1 eye, and 1 eyes underwent trabeculectomy. Conclusion : Gel implant was an effective surgical treatment for open-angle glaucoma and a significant reduction in intraocular pressure and glaucoma medication was observed at with an average follow-up of 10.7 ± 2.4 months . Key Words : Ab interno implantation; Gel implant; Minimally invasive glaucoma surgery; Open-angle glaucoma{{abstract}}eninfo:eu-repo/semantics/openAccessGöz Hastalıkları = Eye DiseasesCerrahi işlemler-minimal girişimsel = Surgical procedures-minimally invasiveCerrahi-göz = Surgery-eyeGlokom = GlaucomaGlokom-geniş açılı = Glaucoma-open angleProtezler ve implantlar = Prostheses and implantsStentler = StentsGöz Hatalıkları Anabilim DalıThesis