Kurklu-Gurleyen, EsmaOgut-Erisen, MerveCakir, OnurUysal, OmerAk, Gulsum2019-10-052019-10-052016-01-01Kurklu-Gurleyen E., Ogut-Erisen M., Cakir O., Uysal O., Ak G., -Quality of life in patients with recurrent aphthous stomatitis treated with a mucoadhesive patch containing citrus essential oil-, PATIENT PREFERENCE AND ADHERENCE, cilt.10, ss.967-973, 2016https://hdl.handle.net/20.500.12645/8706Purpose: To assess 1) patient satisfaction of a mucoadhesive biopatch with citrus essential oil and 2) the change in pain severity and the oral health-related quality of life in patients with recurrent aphthous stomatitis. Patients and methods: Thirty-seven patients with recurrent aphthous stomatitis participated in the study. Baseline records of personal data, ulcer assessment, visual analog scale, and Oral Health Impact Profile-14 were documented. A mucoadhesive patch was applied over the ulcer. Patients were recommended more applications if pain continued. On the fifth day, a post-therapy assessment was made. Results: The mean visual analog scale scores at baseline and posttreatment were significantly different (7.3±2.11 and 4.9±2.6, respectively; P=0.001). The mean duration of pain reduced after patch application. The mean total Oral Health Impact Profile-14 scores before and after treatment showed a statistically significant difference (P=0.001). In total, 78.4% of patients reported a considerable improvement in oral functions after treatment (P=0.008). Conclusion: The mucoadhesive biopatch containing citrus essential oil resulted in satisfying pain alleviation and restoration of oral functions with a significant improvement in the oral health-related quality of life.eninfo:eu-repo/semantics/openAccessArticleWOS:0003768215000018497530237710.2147/ppa.s10653027313450