Ay, Nuray KahramanENHOŞ, ASİMAY, YASİNBakhshaliyev, NijadOzdemir, RazamanNADİR, AYDINKARAÇÖP, ERDEMÇELİKKALE, İLKEULUGANYAN, MAHMUTGoktekin, Omer2019-12-232019-12-232018-11-01Ay N. K. , ENHOŞ A., AY Y., Bakhshaliyev N., NADİR A., KARAÇÖP E., ÇELİKKALE İ., ULUGANYAN M., Ozdemir R., Goktekin O., -The prognostic value of fragmented QRS in patients undergoing transcatheter aortic valve implantation-, JOURNAL OF ELECTROCARDIOLOGY, cilt.51, ss.923-927, 2018https://hdl.handle.net/20.500.12645/10722https://doi.org/10.1016/j.jelectrocard.2018.07.015Background Although transcatheter aortic valve implantation (TAVI) can successfully correct aortic narrowing, pre-existing pathophysiological alterations in the left ventricle are still a concern in terms of long-term mortality. This study aimed to examine the predictive role of fQRS morphology on long-term prognosis in patients undergoing TAVI due to severe aortic stenosis. Methods A total of 117 patients undergoing TAVI due to severe aortic stenosis were included in this retrospective cohort study. Patients were assigned into two groups based on the presence (n = 36) or absence (n = 81) of fQRS. Predictors of long-term survival were estimated. Results In-hospital mortality was higher in fQRS group (5.5% vs. 1.2%, p = 0.0224). In the long-term, fQRS (OR: 3.06, 95% CI 1.29–7.27, p: 0.01), LVEF <50% (OR: 2.54, 95% CI 1.07–6.02, p: 0.03) and presence of atrial fibrillation (OR: 2.42, 95% CI 1.05–5.60, p: 0.03) emerged as significant independent predictors of short survival. Conclusion Presence of fQRS on ECG, an indirect indicator of myocardial fibrosis, seems to have the potential to be used as a prognostic marker after TAVI procedure. Large prospective studies are warranted.Transcatheter aortic valve implantation (TAVI)Aortic stenosisFragmented QRS (fQRS)Myocardial fibrosisPrognosisArticle30497748