Okyaltirik, FATMANURRezvani, AYLİNTuran, SaimeUysal, OmerYAKAR, FatihSÖZGEN, HaticeOzkan, Nazli EzgiAkkoyunlu, Muhammet EminBayram, MEHMETOzcelik, Hatice KutbaySezer, MuratGÜLER, MustafaYaylim, IlhanKart, Levent2019-10-052019-10-052017-09-01Okyaltirik F., Rezvani A., Turan S., Uysal O., YAKAR F., SÖZGEN H., Ozkan N. E. , Akkoyunlu M. E. , Bayram M., Ozcelik H. K. , et al., -Relationship of CTLA4 and CD28 polymorphisms with lung involvement, HRCT findings and pulmonary function tests in Turkish patients with ankylosing spondylitis-, CLINICAL RESPIRATORY JOURNAL, cilt.11, ss.593-601, 2017https://hdl.handle.net/20.500.12645/6184Background and AimsAnkylosing spondylitis (AS) is a multisystem disorder with ocular, pulmonary, and cardiovascular involvement. The incidence of pulmonary involvement varies from 1 to 52%. Abnormal T-cell function-derived immune responses are involved in AS pathogenesis. Numerous genes such as CTLA4 and CD28 control T-cell functions. In this study, we aimed to address the relationship between CTLA4 and CD28 polymorphisms and lung involvement in Turkish patients with AS.enArticle26365494