ULUSAL, Hande ArdaSu, OzlemCEBECI, FilizSAKIZ, DamlanurOnsun, NAHİDE2020-10-292020-10-292010-09-01ULUSAL H. A. , Su O., CEBECI F., SAKIZ D., Onsun N., -Bullous Pemphigoid in a Patient with Psoriasis Treated with Cydosporine-, TURKDERM-ARCHIVES OF THE TURKISH DERMATOLOGY AND VENEROLOGY, cilt.44, ss.167-169, 2010http://hdl.handle.net/20.500.12645/26445http://www.journalagent.com/z4/vi.asp?pdir=turkderm&plng=eng&un=TURKDERM-60590&look4=The concomitant occurrence of psoriasis and bullous pemphigoid has been described previously, but the pathogenic mechanism of this relationship is still unknown. We describe a 34-year-old woman with a 22-year history of plaque-type psoriasis. On the third day of hospitalization, disseminated tense bullae developed on her neck and upper extremities. Histologic examination of biopsy specimen obtained from a vesicular lesion demonstrated a subepidermal blister. Direct immunofluorescence revealed IgG and C3 deposition in a linear pattern at the basement membrane zone. Both diseases were successfully treated with cyclosporine. However, the coexistence of these conditions represents a difficult therapeutic challenge. (Turkderm 2010; 44: 167-9)CydosporineArticleWOS:0002832776000127925164205610.4274/turkderm.44.167