Low-cost voltammetric sensor based on reduced graphene oxide anchored on platinum nanoparticles for robust determination of Favipiravir in real samples

Bouali W.ERK N.Kholafazadehastamal G.Naser M.TIRIS G.2023-01-042023-01-042023-01-01Bouali W., ERK N., Kholafazadehastamal G., Naser M., TIRIS G., "Low-cost voltammetric sensor based on reduced graphene oxide anchored on platinum nanoparticles for robust determination of Favipiravir in real samples", Diamond and Related Materials, cilt.131, 20230925-9635https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85144087617&origin=inwardhttps://hdl.handle.net/20.500.12645/34569© 2022 Elsevier B.V.This research describes a simple, sensitive, and disposable modified glassy carbon electrode constructed using platinum nanoparticles anchored on reduced graphene oxide nanocomposite as a conductive modifier (Pt@rGO/GCE) to detect an anti-coronavirus drug, Favipiravir (FAV). The as-synthesized nanocomposite was characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), energy-dispersive X-ray spectroscopy (EDX), and atomic force microscopy (AFM). Under optimized conditions, the square wave voltammetry (SWV) method was used to determine trace amounts of FAV in real samples. The proposed electrode demonstrated a wide linear concentration range of 3.16 to 100.0 μM with a low detection limit (LOD) of 2.46 μM. Moreover, the developed electrode showed outstanding selectivity in the presence of several interferences with high repeatability and reproducibility. Finally, the developed electrode was applied to detect FAV in human plasma and pharmaceutical samples.info:eu-repo/semantics/openAccessTarımsal BilimlerZiraatTarım MakineleriTarım Alet ve MakineleriBilgi Sistemleri, Haberleşme ve Kontrol MühendisliğiSinyal İşlemeFizikYoğun Madde 1:Yapısal, Mekanik ve Termal ÖzelliklerKimyaTemel BilimlerMühendislik ve TeknolojiAgricultural SciencesAgricultureFarm MachineryAgricultural Tools and MachinesInformation Systems, Communication and Control EngineeringSignal ProcessingPhysicsCondensed Matter 1: Structural, Mechanical and Thermal PropertiesChemistryNatural SciencesEngineering and TechnologyMühendislik, Bilişim ve Teknoloji (ENG)Temel Bilimler (SCI)MühendislikMalzeme BilimiMÜHENDİSLİK, MEKANİKMÜHENDİSLİK, ELEKTRİK VE ELEKTRONİKFİZİK, YOĞUN MADDEMALZEME BİLİMİ, ÇOKDİSİPLİNLİEngineering, Computing & Technology (ENG)Natural Sciences (SCI)ENGINEERINGMATERIALS SCIENCECHEMISTRYPHYSICSENGINEERING, MECHANICALENGINEERING, ELECTRICAL & ELECTRONICPHYSICS, CONDENSED MATTERMATERIALS SCIENCE, MULTIDISCIPLINARYElektronik, Optik ve Manyetik MalzemelerFizik BilimleriGenel KimyaMakine MühendisliğiMalzeme KimyasıElektrik ve Elektronik MühendisliğiElectronic, Optical and Magnetic MaterialsPhysical SciencesGeneral ChemistryMechanical EngineeringMaterials ChemistryElectrical and Electronic EngineeringCovid-19FavipiravirGraphene oxideMetal nanoparticlesPharmaceutical sampleLow-cost voltammetric sensor based on reduced graphene oxide anchored on platinum nanoparticles for robust determination of Favipiravir in real samplesarticle10.1016/j.diamond.2022.109609131