Kurt, AysegulALTINTAŞ, SUBUTAY HANKIZILTAS, Mustafa VolkanTEKKELI, Serife EvrimGuler, ERAY METİNKocyigit, ABDÜRRAHİMUSUMEZ, Aslihan2019-10-052019-10-052018-02-01Kurt A., ALTINTAŞ S. H. , KIZILTAS M. V. , TEKKELI S. E. , Guler E. M. , Kocyigit A., USUMEZ A., -Evaluation of residual monomer release and toxicity of self-adhesive resin cements-, DENTAL MATERIALS JOURNAL, cilt.37, ss.40-48, 2018https://hdl.handle.net/20.500.12645/8252The aim of this study was to evaluate the amount of leached residual monomers from self-adhesive resin cements and evaluate their toxicity in-vitro. A total of 60 disk-shaped specimens (5 mm in diameter and 0.5 mm in thickness) were prepared from each cement (RelyX U200, SpeedCEM, G-Cem) (n=20). Specimens were immersed in artificial saliva and the amount of released monomers [urethane dimethacrylate (UDMA) and triethyleneglycol dimethacrylate (TEGDMA)] was identified. Then, the cytotoxicity and genotoxicity effect on cells were evaluated using the defined amounts of released monomers from cements. The highest monomer release was detected in G-Cem (p<0.05). The highest cytotoxicity value was identified from SpeedCEM (p<0.01) and the highest genotoxicity values were calculated from RelyX U200 (p<0.05). Released UDMA and TEGDMA from self-adhesive resin cements induced cytotoxicity and genotoxicity effect on cells.eninfo:eu-repo/semantics/openAccessArticleWOS:0004306469000068504131084110.4012/dmj.2016-38029225277