Baki, AhmetÖZER, Ömer FarukYildiz, MuhammetKÖKTAŞOĞLU, FATMANUR2020-09-012020-09-012020-07-01Baki A, Özer ÖF, Yıldız M, Köktaşoğlu F. Serum Melatonin Levels in Patients with Sudden Sensorineural Hearing Loss. Bezmialem Science 2020;8(3):269-74.http://hdl.handle.net/20.500.12645/18553Objective: This study aimed to investigate the serum melatonin levels of patients with idiopathic sudden sensorineural hearing loss (ISSNHL). Methods: This study enrolled 22 patients with ISSNHL and 22 asymptomatic healthy volunteers. The subjects underwent pure tone audiometry and serum melatonin levels were measured. Results: The patient group was composed of 12 women (mean age, 46.41 +/- 7.8) and 10 men (mean age, 48 +/- 6.46), and the control group was composed of 12 women (mean age, 40.25 +/- 5.28) and 10 men (mean age, 38.4 +/- 27.08). The serum melatonin levels were significantly lower in the patient group than in the control group (p=0.001). A statistically significant strong negative correlation was found between serum melatonin level and severity of hearing loss (r=-0.644; p=0.001). Conclusion: Serum melatonin levels of patients with ISSNHL were lower than controls. A statistically significant strong negative correlation was found between serum melatonin level and the severity of hearing loss.Sudden hearing lossmelatoninantioxidantArticleWOS:00056070810001110.14235/bas.galenos.2019.3459376435