Akgul, OzgurUyarel, HuseyinPusuroglu, HamdiGul, MehmetIsiksacan, NilgunTuren, SelahattinErturk, MehmetSurgit, OzgurÇETİN, MUSTAFABulut, UmitBaycan, Omer F.Uslu, Nevzat2020-10-222020-10-222013-10-01Akgul O., Uyarel H., Pusuroglu H., Gul M., Isiksacan N., Turen S., Erturk M., Surgit O., ÇETİN M., Bulut U., et al., -Predictive value of elevated D-dimer in patients undergoing primary angioplasty for ST elevation myocardial infarction-, BLOOD COAGULATION & FIBRINOLYSIS, cilt.24, ss.704-710, 2013http://hdl.handle.net/20.500.12645/24296https://www.clinicalkey.com/#!/content/playContent/1-s2.0-S0735109713031653?returnurl=https:%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0735109713031653%3Fshowall%3Dtrue&referrer=https:%2F%2Fapps.webofknowledge.com%2FThe aim of this study was to evaluate the prognostic value of D-dimer in patients with STEMI undergoing primary percutaneous coronary intervention (PCI). The prognostic value of D-dimer has been documented in patients with acute coronary syndrome without ST-segment elevation. However, its value in acute ST-segment elevation myocardial infarction (STEMI) remains unclear. We prospectively enrolled 453 consecutive STEMI patients (mean age 55.6 +/- 12.4 years, 364 male, 89 female) undergoing primary PCI. The study population was divided into tertiles based on admission D-dimer values. The high D-dimer group (n=151) was defined as a value in the third tertile [>0.72ug/ml fibrinogen equivalent units (FEU)], and the low D-dimer group (n=302) included those patients with a value in the lower two tertiles (0.72ug/ml FEU). Clinical characteristics, in-hospital and 6-month outcomes of primary PCI were analyzed. The patients of the high D-dimer group were older (mean age 60.1 +/- 13.5 versus 52.4 +/- 10.6, P0.72ug/ml FEU) was found to be a powerful independent predictor of 6-month all-cause mortality (odds ratio: 10.1, 95% confidence interval: 1.24-42.73, P=0.03). These results suggest that a high admission D-dimer, level was associated with increased in-hospital cardiovascular mortality and 6-month all-cause mortality in patients with STEMI undergoing primary PCI. (C) 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins.D-dimerArticleWOS:0003265983000058488518265610.1097/mbc.0b013e328361039623571687