Kiyak, M. C.Kahraman, F. U.Gedik, A. H.Kocyigit, A.Cakir, F. B.Nursoy, M.Cakir, E.2022-05-242022-05-242022-04-01Kiyak M. C. , Kahraman F. U. , Gedik A. H. , Kocyigit A., Cakir F. B. , Nursoy M., Cakir E., -Serum Myeloperoxidase, Paraoxonase and Arylesterase Enzymes Levels in Children with Bronchiectasis-, HONG KONG JOURNAL OF PAEDIATRICS, cilt.27, sa.2, ss.126-131, 2022http://hdl.handle.net/20.500.12645/30650Background: The aim of this study was to measure the serum levels of myeloperoxidase (MPO), paraoxonase (PON1) and arylesterase (ARE) in paediatric patients with non-cystic fibrosis bronchiectasis (non-CF BE), and to compare these results with healthy controls. Methods: A total of 101 paediatric patients with non-CF BE and 70 age- and sex-matched healthy controls were enrolled into the study between November 2010 and November 2015. The levels of MPO, PON1 and ARE were measured in all participants. Findings: Compared to controls, MPO levels were significantly lower (p=0.001), while PONI and ARE levels were significantly higher in the patient group (p=0.001). Conclusion: Our study reports that the oxidant and anti-oxidant enzyme levels in non-CF BE differ from healthy controls; thus, suggesting a role in non-CF BE pathophysiology.ArticleWOS:00079259980000685129677856