Ozturk, ErdoganSurucu, MuratKaraman, AbdurrahmanŞAMDANCI, EMİNEFadillioglu, Ersin2020-10-222020-10-222014-04-01Ozturk E., Surucu M., Karaman A., ŞAMDANCI E., Fadillioglu E., -Protective effect of leflunomide against oxidative intestinal injury in a rodent model of sepsis-, JOURNAL OF SURGICAL RESEARCH, cilt.187, ss.610-615, 2014http://hdl.handle.net/20.500.12645/24266Background: Sepsis is defined as an uncontrolled inflammatory response in a host. The process may lead to severe sepsis, multisystem organ failure and even death. Leflunomide has important immunomodulatory and anti-inflammatory effects, which may mitigate host response to bacterial translocation. The goal of our study was to measure the effects leflunomide administration had on a variety of biochemical markers upregulated in systemic inflammatory response syndrome, sepsis, and multiple organ failure syndrome.ArticleWOS:0003327706000338490056068110.1016/j.jss.2013.11.00524484905