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Antioxidant and Anticholinesterase Activities of Some Dialkylamino Substituted 3-Hydroxyflavone Derivatives

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Date
2017-01-01
Authors
Culhaoglu, Burcu
Capan, Asli
Boga, Mehmet
Ozturk, Mehmet
Öztürk, Turan
Topcu, Gülaçtı
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Abstract
Background: Flavones, are a class of naturally occuring polyphenolic compounds which have 2-phenylchromen-4-one structure. Various studies showed that flavones have several pharmacological activities such as antioxidant, anti-inflammatory, antimicrobial, cytotoxic, antitumour and antiallergic. In the present study, 3-hydroxyflavones also called flavonols, posessing 4--dialkylamino moiety were synthesized, and their antioxidant and anticholinesterase activities were investigated by comparison with unmodified 3-hydroxflavone.
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Culhaoglu B., Capan A., Boga M., Ozturk M., Öztürk T., Topcu G., -Antioxidant and Anticholinesterase Activities of Some Dialkylamino Substituted 3-Hydroxyflavone Derivatives-, MEDICINAL CHEMISTRY, cilt.13, ss.254-259, 2017
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