Publication: Incidence of Type 1 Diabetes in Children Aged Below 18 Years during 2013-2015 in Northwest Turkey
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Date
2018-11-29
Authors
Authors
POYRAZOĞLU, Ş
BUNDAK, R
Yavaş, Abalı
ÖNAL, H
SARıKAYA, SİYAMİ
AKGÜN, A
BAŞ, S
ABALı, S
BEREKET, A
EREN, E
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Abstract
Objective: To assess the incidence of type 1 diabetes mellitus (T1DM) in children under 18 years of age in the northwest region of Turkey
during 2013-2015.
Methods: All newly diagnosed T1DM cases were recorded prospectively during 2013-2015. Total, as well as gender and age group
specific (0-4, 5-9, 10-14 and 15-17 age) mean incidences per 100,000 per year were calculated.
Results: There were 1,773 patients diagnosed during 2013-2015 (588 cases in 2013, 592 cases in 2014, 593 cases in 2015). Of these,
862 (48.6%) were girls and 911 (51.4%) were boys. The mean age at diagnosis was 9.2±4.2 years and it was not significantly different
between girls (9.0±4.1 years) and boys (9.4±4.4 years) (p=0.052). The crude mean incidence was 8.99/100.000 confidence interval
(CI) (95% CI: 8.58-9.42). Although mean incidence was similar between boys [8.98/100.000 (CI: 8.40 to 9.58)] and girls [9.01/100.000
(CI: 8.42 to 9.63)], there was male predominance in all groups except for 5-9 year age group. The standardized mean incidence was
9.02/100.000 according to the World Health Organization standard population. The mean incidence for the 0-4, 5-9, 10-14 and 15-17 age
groups was 6.13, 11.68, 11.7 and 5.04/100.000 respectively. The incidence of T1DM was similar over the course of three years (p=0.95).
A significant increase in the proportion of cases diagnosed was observed in the autumn-winter seasons.
Conclusion: The northwest region of Turkey experienced an intermediate incidence of T1DM over the period of the study.
Keywords: Type 1 diabetes mellitus, childhood, incidence
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Citation
POYRAZOĞLU Ş., BUNDAK R., Yavaş A., ÖNAL H., SARıKAYA S., AKGÜN A., BAŞ S., ABALı S., BEREKET A., EREN E., et al., -Incidence of Type 1 Diabetes in Children Aged Below 18 Years during 2013-2015 in Northwest Turkey-, Journal of clinical research in pediatric endocrinology, cilt.10, ss.336-342, 2018