Publication: Reversible Corpus Callosum Splenial Lesion Due to Steroid Therapy
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Date
2015-05-01
Authors
AKSU, Banu
Kurtcan, SERPİL
Alkan, ALPAY
Aralasmak, AYŞE
OKTEM, Faruk
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Abstract
Reversible corpus callosum splenial (CCS) lesions are rare findings and usually detected incidentally. We presented a case of 15-year-old boy with a diagnoses of nephrotic syndrome. He was referred for neuropsychiatric symptoms following dose reduction on steroid treatment. Brain magnetic resonance imaging (MRI) revealed a focal lesion in the CCS, hyperintense on T2 and FLAIR and hypointense on T1 images with diffusion restriction on apparent diffusion coefficient map. Follow-up MRI 3 weeks later showed complete resolution of the lesion. It was probably result of focal intramyelinic edema due to excytotoxic mechanisms and/or arginine-vasopressin release.
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AKSU B., Kurtcan S., Alkan A., Aralasmak A., OKTEM F., -Reversible Corpus Callosum Splenial Lesion Due to Steroid Therapy-, JOURNAL OF NEUROIMAGING, cilt.25, ss.501-504, 2015