Publication:
Diffuse reflectance spectroscopy for the measurement of tissue oxygen saturation

No Thumbnail Available
Date
2015-12-01
Authors
Sircan-Kucuksayan, A.
Uyuklu, MEHMET
CANPOLAT, MURAT
Journal Title
Journal ISSN
Volume Title
Publisher
Research Projects
Organizational Units
Journal Issue

Metrics

Search on Google Scholar

Abstract
Tissue oxygen saturation (StO(2)) is a useful parameter for medical applications. A spectroscopic method has been developed to detect pathologic tissues, due to a lack of normal blood circulation, by measuring StO(2). In this study, human blood samples with different levels of oxygen saturation have been prepared and spectra were acquired using an optical fiber probe to investigate the correlation between the oxygen saturation levels and the spectra. A linear correlation between the oxygen saturation and ratio of the intensities (760 nm to 790 nm) of the spectra acquired from blood samples has been found. In a validation study, oxygen saturations of the blood samples were estimated from the spectroscopic measurements with an error of 2.9%. It has also been shown that the linear dependence between the ratio and the oxygen saturation of the blood samples was valid for the blood samples with different hematocrits. Spectra were acquired from the forearms of 30 healthy volunteers to estimate StO(2) prior to, at the beginning of, after 2 min, and at the release of total vascular occlusion. The average StO(2) of a forearm before and after the two minutes occlusion was significantly different. The results suggested that optical reflectance spectroscopy is a sensitive method to estimate the StO(2)levels of human tissue. The technique developed to measure StO(2) has potential to detect ischemia in real time.
Description
Keywords
Citation
Sircan-Kucuksayan A., Uyuklu M., CANPOLAT M., -Diffuse reflectance spectroscopy for the measurement of tissue oxygen saturation-, PHYSIOLOGICAL MEASUREMENT, cilt.36, ss.2461-2469, 2015
Collections
Page Views

0

File Downloads

0

Sustainable Development Goals