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Diffuse reflectance spectroscopy for the measurement of tissue oxygen saturation

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Date
2015-12-01
Author
CANPOLAT, MURAT
Sircan-Kucuksayan, A.
Uyuklu, MEHMET
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Type
Article
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Abstract
Tissue oxygen saturation (StO(2)) is a useful parameter for medical applications. A spectroscopic method has been developed to detect pathologic tissues, due to a lack of normal blood circulation, by measuring StO(2). In this study, human blood samples with different levels of oxygen saturation have been prepared and spectra were acquired using an optical fiber probe to investigate the correlation between the oxygen saturation levels and the spectra. A linear correlation between the oxygen saturation and ratio of the intensities (760 nm to 790 nm) of the spectra acquired from blood samples has been found. In a validation study, oxygen saturations of the blood samples were estimated from the spectroscopic measurements with an error of 2.9%. It has also been shown that the linear dependence between the ratio and the oxygen saturation of the blood samples was valid for the blood samples with different hematocrits. Spectra were acquired from the forearms of 30 healthy volunteers to estimate StO(2) prior to, at the beginning of, after 2 min, and at the release of total vascular occlusion. The average StO(2) of a forearm before and after the two minutes occlusion was significantly different. The results suggested that optical reflectance spectroscopy is a sensitive method to estimate the StO(2)levels of human tissue. The technique developed to measure StO(2) has potential to detect ischemia in real time.
Subject
Sircan-Kucuksayan A., Uyuklu M., CANPOLAT M., -Diffuse reflectance spectroscopy for the measurement of tissue oxygen saturation-, PHYSIOLOGICAL MEASUREMENT, cilt.36, ss.2461-2469, 2015
URI
https://hdl.handle.net/20.500.12645/3042
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BEZMIALEM VAKIF UNIVERSITY

About us |Policies | Library | Contact us | Send Feedback | Sitemap | Admin

Bezmialem Vakıf Üniversitesi, Adnan Menderes Bulvarı Vatan Caddesi 34093 Fatih, İstanbul / TURKEY
Copyright © Bezmialem Vakıf Üniversitesi

Creative Commons Lisansı
Bezmialem Institutional Repository, Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.

OpenAccess@BVU

Support by  UNIREPOS