İstanbul Üniversitesi
Recent Submissions
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Default mode and dorsal attention network involvement in visually guided motor sequence learning
(2022-01-01)Motor sequence learning (MSL) paradigms are often used to investigate the neural processes underlying the acquisition of complex motor skills. Behavioral and neuroimaging studies have indicated an early stage in which ... -
The genetic structure of the Turkish population reveals high levels of variation and admixture
(2021-09-01)The construction of population-based variomes has contributed substantially to our understanding of the genetic basis of human inherited disease. Here, we investigated the genetic structure of Turkey from 3,362 unrelated ... -
Copy Number Variation Analysis with Next Generation Sequencing
(2020-12-14)Copy Number Variation Analysis with Next Generation Sequencing Bülent Uyanık1 , Sezin Canbek2 1 Bezmialem Vakıf Üniversitesi Tıp Fakültesi Tıbbi Genetik ABD. 2 Sağlık Bilimleri Üniversitesi Ümraniye Eğitim ve Araştırma ... -
A Comprehensive Review: Molecular and Genetic Background of Indirect Inguinal Hernias
(2021-04-01)Background: The occurrence of indirect inguinal hernias (IIH) is 5 times more prevalent than that of direct inguinal hernias (IH) and it is 7 times more common in males, owing to the attendance of the processus vaginalis ... -
Assessing the influence of cycloastragenol on telomere/telomerase system of Arabidopsis thaliana
(2021-03-01)Cycloastragenol (CAG) is a triterpenoid saponin compound that is synthesized by Astragalus species. CAG has many bioactivity, including telomerase activation, telomere elongation, anti-inflammatory, and anti-oxidative ... -
The role of typical and atypical pathogens in acute exacerbations of chronic obstructive pulmonary disease
(2020-10-01)Objectives The exact role of Mycoplasma pneumoniae, Chlamydophila pneumoniae, and Legionella pneumophila in the development of chronic obstructive pulmonary disease exacerbations remains to be elucidated. This study was ... -
Valeriana officinalis extract and 7-Nitroindozole ameliorated seizure behaviours, and 7-Nitroindozole reduced blood pressure and ECG parameters in pentylenetetrazole-kindled rats
(2020-01-01)Nitric oxide (NO) is known to be a neuromodulator with dual proconvulsive and anticonvulsive action. Valeriana officinalis (VAL) was previously believed to be antiepileptic, but is today known as a sedative and sleep ... -
Inhibition and destruction of Pseudomonas aeruginosa biofilms by antibiotics and antimicrobial peptides
(2014-12-01)Pseudomonas aeruginosa is one of the major nosocomial pathogen that can causes a wide variety of acute and chronic infections P. aeruginosa is a dreaded bacteria not just because of the high intrinsic and acquired antibiotic ... -
Eplerenone nanoemulsions for treatment of hypertension. Part II: Physical stability assessment and in vivo study
(2018-06-01)The aim of the present complimentary study was to investigate physical stability of eplerenone (EP) loaded nanoemulsions and to evaluate their pharmacokinetic profiles after subcutaneous application to Sprague Dawley rats. ...
