Publication: T3SEdb: data warehousing of virulence effectors secreted by the bacterial Type III Secretion System
No Thumbnail Available
Date
2010-10-01T00:00:00Z
Authors
Authors
Tay, Daniel Ming Ming
Govindarajan, Kunde Ramamoorthy
KHAN, MOHAMMAD ASİF
Ong, Terenze Yao Rui
Samad, Hanif M.
Soh, Wei Wei
Tong, Minyan
Zhang, Fan
Tan, Tin Wee
Journal Title
Journal ISSN
Volume Title
Publisher
Metrics
Abstract
Background: Effectors of Type III Secretion System (T3SS) play a pivotal role in establishing and maintaining pathogenicity in the host and therefore the identification of these effectors is important in understanding virulence. However, the effectors display high level of sequence diversity, therefore making the identification a difficult process. There is a need to collate and annotate existing effector sequences in public databases to enable systematic analyses of these sequences for development of models for screening and selection of putative novel effectors from bacterial genomes that can be validated by a smaller number of key experiments.
Description
Keywords
Citation
Tay D. M. M. , Govindarajan K. R. , KHAN M. A. , Ong T. Y. R. , Samad H. M. , Soh W. W. , Tong M., Zhang F., Tan T. W. , -T3SEdb: data warehousing of virulence effectors secreted by the bacterial Type III Secretion System-, BMC BIOINFORMATICS, cilt.11, 2010